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Publication in SLEEP Journal Demonstrates Positive Results of Large Multi-Center Clinical Trial for Provent® Sleep Apnea Therapy
Date:4/4/2011

p>Results at the start of the study showed that AHI was reduced by 52.7 percent in the Provent Therapy group compared to a 7.3 percent reduction in the sham group, representing a highly significant treatment effect (p<0.0001). A highly significant improvement in AHI was also demonstrated at the conclusion of the study. Using the Epworth Sleepiness Scale to evaluate daytime sleepiness, patients using Provent Therapy showed improved alertness, reducing sleepiness from 9.9 +/- 4.7 to 7.2 +/- 4.2 compared to the sham group of 9.6 +/- 8.3 to 8.3 +/- 5.1 , a statistically significant improvement compared to the sham group (p=0.04). Importantly, self-reported patient adherence was excellent, with the Provent Therapy device worn all night for 88.2 percent of nights in the study.

"CPAP is the gold standard in the treatment for obstructive sleep apnea, but unfortunately many patients who are prescribed CPAP cannot get used to it, or use it less often than they should," stated study author Meir Kryger, M.D., director of sleep medicine research and education at Gaylord Hospital in Wallingford, Connecticut and former president of the American Academy of Sleep Medicine. "This large trial provides solid clinical data validating Provent Therapy as an important treatment alternative for obstructive sleep apnea."  

About Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is the most common type of sleep-disordered breathing. It is estimated that 40 million people in the United States suffer from sleep apnea. In people with OSA, the airway collapses during sleep when the muscles, that hold the airway open, relax. People with this disorder can stop breathing while sleeping---in some cases hundreds of times each night---usually for periods of ten seconds or longer. Importantly, many recent studies have shown that people with OSA experience higher rates of car accidents as well as serious health problems including high blood pressure, heart attack,
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SOURCE Ventus Medical, Inc.
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