Navigation Links
Prostate Cancer Immunotherapy Significantly Prolongs Survival in Men With Advanced Prostate Cancer
Date:4/28/2009

Phase 3 IMPACT Trial Results to be presented during late-breaking session at AUA Annual Scientific Meeting

CHICAGO, April 28 /PRNewswire-USNewswire/ -- Sipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago. These data from the Phase 3 Immunotherapy for Prostate AdenoCarcinoma Treatment (IMPACT) study were presented during the meeting's Late Breaking Science Forum. A special session for interested media will take place at 3:00 p.m. CT in the AUA Press Suite, room CC22 at the Hyatt Regency McCormick.

Compared to placebo, sipuleucel-T extended median survival by 4.1 months and improved three-year survival by 38 percent. Sipuleucel-T successfully exceeded the pre-specified level of statistical significance defined by the study's design and reduced the overall risk of death by 22.5 percent compared to placebo (p-value=0.032). More than 500 patients were enrolled in the IMPACT trial, a multi-center, randomized, double-blind, placebo-controlled study evaluating men with asymptomatic or minimally symptomatic, metastatic, androgen-independent prostate cancer. The primary endpoint was overall survival.

Researchers are encouraged by the findings, citing an impressive effect on long-term survival for patients, compared to placebo.

"The ability to boost survival for patients is the gold standard endpoint in prostate cancer clinical trials," said AUA spokesperson Ira D. Sharlip, MD. "The ability to give these patients both increased survival and possibly, improved quality of life, is very important."

Sipuleucel-T is an investigational therapy for men with androgen-independent prostate cancer. It is an active cellular immunotherapy designed to use live human cells to boost a patient's immune system to elicit a long-lasting response against cancer.

For more information about this presentation, please contact AUA Communications Manager Wendy Waldsachs Isett at 410-977-4770. Dial-in information for the April 28 press conference is available for those reporters unable to attend the session in person.

About the American Urological Association: Founded in 1902 and headquartered near Baltimore, Maryland, the American Urological Association is the pre-eminent professional organization for urologists, with more than 16,000 members throughout the world. An educational nonprofit organization, the AUA pursues its mission of fostering the highest standards of urologic care by carrying out a wide variety of programs for members and their patients.

    Contact: Wendy Waldsachs Isett, AUA
    Cell: 410-977-4770
    AUA On-Site Press Suite
    312-528-8253


'/>"/>
SOURCE American Urological Association
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
2. Use it or Lose it: A New Theory About Preserving Erectile Function After Prostate Surgery
3. Gene Fusion Subtypes in Prostate Carcinoma Have Clinical Implications
4. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
5. Peregrine Reports Data Showing Bavituximabs Potential to Shrink Prostate Tumors
6. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
7. Study Suggests Soy Protein May Reduce Prostate Cancer Risk
8. Dendreon Completes Target Enrollment of 500 Patients in Phase 3 IMPACT Study of Provenge(R) For Advanced Prostate Cancer
9. Medivations MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial
10. Prostate Cancer Treatment Centre Receives Funding for Clinical Trials
11. Interim Analysis Supports Continuation of Cell Genesys VITAL-1 Phase 3 Clinical Trial of GVAX Immunotherapy for Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... May 5, 2016 Research and Markets has ... in Top 5 EU Markets"  report to their offering.  ,     ... provides information on the current Positron Emission Tomography (PET) scanner ... (T5 EU), which includes France , ... Spain and the United Kingdom ...
(Date:5/5/2016)... Research and Markets has ... Lupus Erythematosus Market and Competitive Landscape Highlights ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO )  ... Lupus Erythematosus Market and Competitive Landscape Highlights ... Lupus Erythematosus pipeline products, Systemic Lupus Erythematosus ...
(Date:5/4/2016)... ZIONA, Israel , May 4, 2016 ... BVXV) announced today that BiondVax,s CEO, Dr. Ron Babecoff ... in New York City . ... 10:30am at Pioneers 2016, a conference presented by Joseph ... Palace Hotel. The BiondVax presentation that Dr. Babecoff ...
Breaking Medicine Technology:
(Date:5/5/2016)... ... 05, 2016 , ... In an effort to increase public ... health promotion and research organization, declared May as “National Sunshine Month.” , ... in cultural behavior over the past several decades, Americans spend more time indoors ...
(Date:5/5/2016)... ... May 05, 2016 , ... The Wisconsin ... Lombardo, PT, DPT, MA, OCS, WCS, has been selected by the Wisconsin Physical ... The WPTA Private Practice Award is awarded annually to a member of the ...
(Date:5/4/2016)... ... ... “Less than 15% of organizations nationwide can be characterized as a Certified Service ... to participate and complete the training, we are very proud to have been recognized ... we invest in volunteer engagement, we can expect $3-$6 in return.” , Points ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... interview techniques, seeks to add a deeper understanding of the program, policy or ... and each answers different yet important questions. , In a new brief released ...
(Date:5/4/2016)... ... May 04, 2016 , ... Cirius, a provider of ... innovative Secure Messaging platform, which includes secure, private messaging, large file sharing, secure ... portfolio of patents around innovative features for securing, tracking, and controlling messages for ...
Breaking Medicine News(10 mins):