Navigation Links
Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients
Date:4/10/2008

ients were still receiving prophylaxis), the investigators observed no statistical differences between measures of CMI and clinical condition of the patients. However, beginning six months after transplantation, when prophylaxis was stopped, there were significant differences in CMI between clinically stable patients (188 ng/mL ATP) and those with evident infections documented by microbial analysis of BAL (91 ng/mL ATP; p < 0.001). The median ImmuKnow measure of CMI based on samples from 45 patients diagnosed with fungal colonization (but no clinical infection) was 188 ng/mL ATP, which was not significantly different from the median value of samples from all clinically stable patients. However, this CMI value was significantly higher than the value in the six transplant patients with fungal disease (78 ng/mL ATP; p < 0.01).

"This study expands our understanding of the applicability of the ImmuKnow immune function assay in effective management of lung transplant recipients in the post-transplant setting," stated Dr. Husain. "While we had demonstrated an association between infection and low ImmuKnow values in an earlier study, we now have specific preliminary prospective evidence that will guide us in predicting risk for fungal infection in these immune-suppressed patients over time."

Dr. Husain's presentation was entitled, "Use of an immune monitoring assay to distinguish between fungal colonization and fungal disease in lung transplant recipients." Dr. Husain is currently Assistant Professor of Medicine and Director of Transplant Infectious Diseases in the Division of Infectious Diseases and Multi-Organ Transplantation, Toronto General Hospital- University Health Network, Toronto, Canada.

About ImmuKnow(R)

ImmuKnow is an immune cell function assay that can detect cell-mediated immunity (CMI) in adult immunosuppressed patients by measuring the concentration of adenosine triphosphate (ATP) released from CD4 cells following cell stimulation
'/>"/>

SOURCE Cylex
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Federal Funding Awarded to Test Antimicrobial Properties of Copper Metals
2. Advanced Life Sciences to Present Data on Selected Cethromycin Therapeutic Studies at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
3. Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces
4. Promising Data from Paratek Pharmaceuticals MAR Inhibitor Program Presented in Late Breaker Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
5. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
6. D1 Sports Training Facilities Adopt TurfAide(TM) Antimicrobial to New Synthetic Turf Fields from AstroTurf(R)
7. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
8. Congressional Funds Awarded for Testing of Antimicrobial Copper Metals
9. Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
10. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
11. New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... , Aug. 27, 2014  CVS Caremark (NYSE: ... into a new clinical affiliation with MedStar Health, a ... Maryland and the Washington, ... high-quality, affordable health care services for patients. Through this ... access to clinical support, medication counseling, chronic disease monitoring ...
(Date:8/27/2014)... 2014  UBM Medica US announces that ... medical imaging professionals, presents special reporting about diagnostic imaging ... 2014 Annual Meeting . Among the ... 11 Principles of Successful Labor Management in Radiology ... , Why Don,t Patients Know the Truth ...
(Date:8/27/2014)... , Aug. 27, 2014 /PRNewswire-iReach/ -- Emergency ... design, blended emergency medical training and response technologies, ... defibrillator) training from the Department of Homeland ... Reserve 81 st Regional Support Command ... contract includes nationwide CPR/AED/First Aid training. The Army ...
Breaking Medicine Technology:CVS Caremark Announces New Clinical Affiliation with MedStar Health 2CVS Caremark Announces New Clinical Affiliation with MedStar Health 3Diagnostic Imaging Covers Association for Medical Imaging Management (AHRA) 2014 Meeting 2Diagnostic Imaging Covers Association for Medical Imaging Management (AHRA) 2014 Meeting 3Emergency University Equips Homeland Security, Army Reserve with SCA Response Program to Save Lives of Sudden Cardiac Arrest Victims 2Emergency University Equips Homeland Security, Army Reserve with SCA Response Program to Save Lives of Sudden Cardiac Arrest Victims 3
... SAN DIEGO, Oct. 26 Sequenom, Inc. (Nasdaq: ... been appointed as the company,s interim chief financial officer ... interim chief executive officer and chairman of the board, ... http://www.newscom.com/cgi-bin/prnh/20040415/SQNMLOGO ) , Prior to the effective date of ...
... of Clinical Cardiovascular Practices to Promote Practice Innovation ... The American College of Cardiology today announced ... registry-based cardiovascular network to link thousands of cardiology ... National Cardiovascular Data Registry(R) (NCDR), the preeminent cardiovascular ...
Cached Medicine Technology:Sequenom Announces Paul Maier to Become Interim Chief Financial Officer 2Sequenom Announces Paul Maier to Become Interim Chief Financial Officer 3American College of Cardiology Launches the Nation's First Registry-Based Cardiovascular Practice Network 2American College of Cardiology Launches the Nation's First Registry-Based Cardiovascular Practice Network 3
(Date:8/27/2014)... Georgia State University’s Center for ... $600,000 grant from the Maternal and Child Health ... to support implementation of the Autism Plan for ... youth with autism spectrum disorder. , In preparing ... Advisory Council composed of key stakeholders from across ...
(Date:8/27/2014)... and dad, especially when your infant looks at you ... prattling, but by listening and responding, they let their ... forming complex sounds and using language more quickly. , ... of Iowa and Indiana University that found how parents ... way infants communicate and use vocalizations. , The findings ...
(Date:8/27/2014)... For nearly two decades, audiences around the ... singers Deva Premal & Miten with their rapturous Nepali ... latest album in May, their 2014 MANTRAS FOR LIFE ... the globe, including Russia, Ukraine, Israel, Australia, the U.S., ... a new album and a new five-piece band, the ...
(Date:8/27/2014)... 27, 2014 The American Brain ... of the 2014-2016 Basic Research Fellowships and 2014-2015 Discovery ... the ABTA is seeding the field with talented, bright ... understanding of the causes, effects, diagnosis and treatment of ... scientific committee based on the potential to advance the ...
(Date:8/27/2014)... the onset of a cancer defense mechanism known ... Cancer Center are leveraging it in a new ... cell death rather than survival. The novel treatment ... referred to as the "Trash Man" due to ... autophagy. Results from preclinical experiments suggest this experimental ...
Breaking Medicine News(10 mins):Health News:Center for Leadership in Disability Awarded $600,000 Grant to Improve Services for Georgia’s Children and Youth with Autism 2Health News:Parents, listen next time your baby babbles 2Health News:Parents, listen next time your baby babbles 3Health News:Deva Premal & Miten's Mantras For Life Tour Announced 2Health News:Deva Premal & Miten's Mantras For Life Tour Announced 3Health News:American Brain Tumor Association Awards New Research Grants to Best and Brightest Investigators 2Health News:American Brain Tumor Association Awards New Research Grants to Best and Brightest Investigators 3Health News:Promising new cancer therapy uses molecular 'Trash Man' to exploit a common cancer defense 2
... to be a major complication of diabetes, despite the ... amputations are currently performed among the diabetic population. ... in the retinas of about 900 diabetic patients who ... All were followed for 20 years to assess how ...
... new study shows hydrotherapy, or water exercise, may improve strength ... Australia studied more than 100 patients with osteoarthritis who were ... The first group exercised three times a week in a ... third did not exercise at all. Both the water and ...
... Chronic lung disease is a primary long-term complication among ... are at greater risk for pulmonary hypertension and impaired ... risk of developing neurological problems. ,A new ... benefit from treatment with inhaled nitric oxide. ,Researchers ...
... pain, pelvic pressure, frequent urination or abnormal periods, uterine ... found in the uterus and can// range in size ... or larger. Now, there’s an improvement to uterine fibroid ... choice for many women. ,Sabrina Figueroa considers herself ...
... back pain is when symptoms have lasted for less ... program that includes group classes, exercise sheet// handouts, and ... their back pain. ,Researchers from Indiana University ... low back pain. The program focuses on boosting confidence ...
... years, Keith Black, M.D., from Cedars-Sinai Medical Center in Los ... cancer. While his research moves forward, he’s helping patients ... tumor vaccine. Dr. Black says brain tumors ... the immune system could use to recognize the tumor. By ...
Cached Medicine News:Health News:Uterine Fibroid Embolization Gaining Popularity 2Health News:New vaccine for brain cancer 2
This product is for the lower body and uses a Convective Warming System which is both soft and comfortable. Constructed of 2-ply material consisting of polyethylene film inner layer and non-woven out...
The torso blanket is designed to affix to the lower abdominal area and cover the upper half of the body....
The fabric is antistatic and non-linting and is both oil and water repellent.These superior blankets are an environmental friendly alternative to disposable blankets....
CritiCool™ offers precise cooling to the programmed target temperature by applying temperature control algorithm....
Medicine Products: