Navigation Links
Promising Parkinson's Disease Research Highlighted by The Michael J. Fox Foundation to Accelerate Drug Development
Date:7/11/2013

NEW YORK, July 11, 2013 /PRNewswire-USNewswire/ -- Research projects from five biopharmaceutical companies in the United States, Canada and Israel comprise the 2013 first half (1H 2013) of The Michael J. Fox Foundation for Parkinson's Research (MJFF) Partnering Program. Among the most promising in the MJFF portfolio, Partnering Program participants' research projects are presented directly to industry groups who may wish to invest in further development of the project. By connecting industry leaders with those studies ripe for investment, the Foundation aims to drive forward promising research in Parkinson's disease (PD) through the pipeline of drug development and eventually into patients' hands.

Non-confidential overviews of the selected MJFF-funded projects are shared with industry contacts and more broadly via MJFF's Web site twice yearly in July and December (previously quarterly).

Selected for the MJFF Partnering Program 1H 2013 are:

Disease-Modifying Research

  • Ceregene's clinical research on a gene delivery approach to neurotrophic factors (which can have a restorative effect on degenerating neurons) did not meet its primary endpoint, but saw some effects on secondary measures that suggest some benefits. Ceregene continues to analyze this data to identify areas for future research.
  • MedGenesis' investigation of GDNF, a biological neurotrophic factor and potential disease-modifying therapy. MedGenesis has in-licensed the product from Amgen and has developed an enhanced delivery paradigm to overcome previous limitations.
  • NeuroPhage Pharmaceuticals' study of NPT002, a potential disease-modifying therapy for PD that targets alpha-synuclein.  NPT002 binds, disaggregates and prevents the formation of multiple amyloidogenic structures. This novel approach has increased therapeutic potential as it targets both early amyloid assemblies as well as pre-existing aggregates.

Symptomatic Research

  • Cynapsus Therapeutics' development of APL-130277, a novel formulation of the drug apomorphine, as a rescue medication for intermittent OFF episodes in PD. APL-130277 is a thin film strip that dissolves under the tongue.
  • NeuroDerm's clinical research on continuous administration of levodopa and carbidopa through a "pump-patch." This technology could maintain continuous and constant concentration of levodopa in the blood, which should significantly decrease motor fluctuations and possibly reverse dyskinesia.

To date, the Foundation has funded $325 million in research, more than $84 million of which has been directed to over 185 unique projects led by industry partners.

For more information on the MJFF Partnering Program 1H 2013 participants and previously featured grantees, visit https://www.michaeljfox.org/research/opportunities-for-industry/partnering-program.html. The MJFF Research Partnerships team can be reached at ResearchPartnerships@michaeljfox.org.


'/>"/>
SOURCE The Michael J. Fox Foundation
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Adult and Adolescent Vaccines Market to 2018 Report - Promising Novel Candidates in Late-Stage Development and Prevnar Approval for Use in Adults to Drive Growth
2. QIAGEN Expands Pipeline of Promising New Biomarkers for Development of Personalized Healthcare Companion Diagnostics
3. Novan Announces Promising Results of SB204 Clinical Study
4. International Mesothelioma Experts Present Promising New Research Findings at the 3rd Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma
5. Use Of Cryoablation For Treatment Of Breast Cancer Shows Promising Results
6. Statement from the Cystic Fibrosis Foundation on Promising Phase 2 Clinical Trial Results of Kalydeco and VX-661 (Vertex Pharmaceuticals Inc.)
7. University of Michigans Zell Lurie Institute Awards $112,000 to Promising Student Startups in 30th Annual Business Plan Competition and Dare to Dream Grant Program
8. Forbes Ranks SynCardia Among "Americas Most Promising Companies" for Second Straight Year
9. Meth Vaccine Shows Promising Results in Early Tests
10. Epigenetics R&D Pipeline - Histone Deacetylases (HDACs) Offer the Most Promising Targets and Outnumber Other Classes of Epigenetic Targets
11. Boston Scientific Announces Promising Clinical Data on New Products at the International Spine Intervention Society 20th Annual Scientific Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2017)... SPRING, Md. , March 29, 2017 On March ... (ocrelizumab) to treat adult patients with relapsing forms of ... This is the first drug approved by the FDA ... a health care professional.  "Multiple sclerosis ... said Billy Dunn , M.D., director of the ...
(Date:3/29/2017)... FinancialBuzz.com News Commentary  ... The U.S. could see significant economic benefits from the expanding ... Frontier Data, the legal cannabis market is projected to create 283,422 ... the United States , as well as the economic ... that drives growth in this sector. Medical cannabis is now legal ...
(Date:3/28/2017)... 28, 2017 "Chemotherapy Induced Neutropenia (CIN) – Market Insights, ... and global market trends of the Chemotherapy Induced Neutropenia for the ... Europe ( France , ... , UK) and Japan , as well ... of the world (RoW). The Report covers the therapeutics ...
Breaking Medicine Technology:
(Date:3/29/2017)... ... March 29, 2017 , ... The assembly ... assembly protocols involve many repetitive steps and often scientists require many different versions ... high-throughput needed, and results in a lower error rate and cost saving for ...
(Date:3/29/2017)... , ... March 29, 2017 , ... ... Gastrointestinal Oncology™ (SOGO™), a specialized continuing medical education conference for clinicians who manage ... Intercontinental Time Square, New York. , The program will be led by ...
(Date:3/28/2017)... ... March 28, 2017 , ... A recent Bellwether Education Partners’ ... the field must first improve teacher preparation program design. It then asserts that ... that decades of input- and outcome-based research has failed to improve teacher education. ...
(Date:3/28/2017)... ... March 28, 2017 , ... Greenfield ... Williamson brings his extensive knowledge of appraisals, property values, ad valorem taxation, and ... estate valuation industry for more than 40 years. , “Ruel is a great ...
(Date:3/28/2017)... ... March 29, 2017 , ... Dr. Isabella Wentz, PharmD, ... a 9-part video series titled The Thyroid Secret. Dr. Wentz talked about journey and ... emphasizes the fact that medication IS NOT the only solution to deal with thyroid ...
Breaking Medicine News(10 mins):