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Prometheus Launches ProOnc Dx Cancer Diagnostics
Date:10/15/2009

SAN DIEGO, Oct. 15 /PRNewswire/ -- Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, today announced the nationwide commercial launch of three new cancer diagnostic products: ProOnc TumorSource Dx, ProOnc Squamous Dx and ProOnc Mesothelioma Dx. Each of these tests is based on recently developed, highly sensitive microRNA technology.

"Prometheus has a long and successful history of providing innovative diagnostics that complement targeted therapeutics to help physicians individualize patient care," said Joseph M. Limber, President and Chief Executive Officer of Prometheus. "Now we are proud to introduce the first three products from our cancer diagnostics portfolio with the launch of ProOnc Dx. We believe that these highly tissue-specific tests provide more objective and quantitative results than current methods, which, may lead to more personalized treatments for patients."

ProOnc TumorSource Dx identifies the tissue-of-origin of a metastatic tumor. The test identifies 25 different tumor types, including colon, liver, brain, breast, kidney, lung, ovary, pancreas, prostate and testis, and measures the expression level of 48 microRNA biomarkers. ProOnc TumorSource Dx uses a proprietary classifier to assign a primary site to the cancer sample based on the microRNA expression in the tumor and may become a critical tool in the detection of cancer of unknown primary (CUP).

ProOnc Squamous Dx classifies non-small cell lung carcinoma tumors into two histological groups: cancers of squamous histology and non-squamous cancers. The test measures the expression level of a squamous microRNA biomarker to differentiate patients that have squamous cell carcinoma of the lung from patients that have non-squamous non-small cell lung cancer.

ProOnc Mesothelioma Dx is a cutting-edge molecular diagnostic test that uses microRNA to differentiate malignant pleural mesothelioma from peripheral adenocarcinoma
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SOURCE Prometheus Laboratories Inc.
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