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Prometheus Launches New Monitoring Test To Help Guide Inflammatory Bowel Disease Management
Date:7/31/2012

SAN DIEGO, July 31, 2012 /PRNewswire/ -- Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced today the market launch of its proprietary new generation monitoring test, PROMETHEUS Anser IFX.  This test measures drug (infliximab) and drug antibody levels in one sample among inflammatory bowel disease (IBD) patients using infliximab – helping physicians identify potential causes for loss of treatment response and helping to guide patient management decisions. This is the first commercial test utilizing Prometheus' proprietary homogenous mobility shift assay (HMSA) platform technology. Prometheus intends to use this platform for subsequent introductions of additional tests targeted to other biologic agents being used to treat a variety of autoimmune diseases.

The Crohn's and Colitis Foundation of America estimates that approximately 1.4 million Americans suffer from IBD.  Approximately 50% of IBD patients using infliximab may eventually experience a loss of treatment response during their treatment.  For some patients, this loss of treatment response may be the result of insufficient infliximab levels.  For others, the loss may be due to the development of antibodies to infliximab (ATI).  If the loss of treatment response is due to the development of ATI, increasing the infliximab dose – the most common first step for physicians – may be less effective than switching to another treatment agent. PROMETHEUS Anser IFX test was verified with more than 3,000 IBD clinical patient samples.

"The need for PROMETHEUS Anser IFX is high, and its availability marks the latest milestone in our continuing commitment to significant advancements in personalized medicine for gastroenterologists, patients and healthcare providers," said Joseph M. Limber, President and Chief Executive Officer of Prometheus.  "PROMETHEUS Anser IFX provides significant value to the IBD patient using inflix
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SOURCE Prometheus Laboratories Inc.
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