Navigation Links
Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients
Date:12/8/2008

ith 7 percent in the VAD arm (p=0.0035). -- After the first performed ASCT, CR/nCR rates were 40 percent in the VcD arm, compared with 22 percent in the VAD arm (p=0.0001). -- After the first performed ASCT, very good partial response (VGPR) or better rates were 61 percent in the VcD arm, compared with 44 percent in the VAD arm (p=0.0007). -- Thirty-four percent of patients in the VcD arm required a second ASCT, compared with 47 percent of patients in the VAD arm. -- Serious adverse events were reported in 27 percent of the VcD patients, compared with 34 percent of the VAD patients.

"The data from patients treated with VELCADE and dexamethasone prior to transplantation showed significantly longer progression-free survival," said Jean-Luc Harousseau, M.D., Hospital Hotel-Dieu and Principal Investigator of the trial. "We are interested in whether this will translate into extended overall survival for these patients with previously untreated multiple myeloma when the follow-up duration is sufficient."

Patients in the VcD arm received VELCADE at 1.3 mg/m(2) on days 1, 4, 8 and 11 and dexamethasone at 40 mg on days 1 through 4 during cycles 1 through 4 and days 9 through 12 during only the first and second cycles. Patients in the VAD arm received vincristine at 0.4 mg/m(2) and doxorubicin at 9 mg/m(2) on days 1 through 4, and dexamethasone at 40 mg on days 1 through 4 during cycles 1 through 4 and on days 9 through 12 and 17 through 20 during only the first and second cycles.

Superior Complete Response Rate and Progression-Free Survival After Autologous Transplantation with Up-Front VELCADE-Thalidomide-Dexamethasone Compared with Thalidomide-Dexamethasone in Newly Diagnosed Multiple Myeloma (Abstract #158)

In a Phase III study conducted by the Italian Myeloma Network GIMEMA, researchers compared VcTD with TD as induction therapy in
'/>"/>

SOURCE Millennium: The Takeda Oncology Company
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Nebulized Perforomist(TM) Inhalation Solution Provided Prolonged Bronchodilation and Increased Patient Satisfaction Compared to Albuterol/Ipratropium MDI
2. Ipilimumab Plus Chemotherapy is Associated with Prolonged Survival and Increased Disease Control Rates in Patients with Advanced Melanoma
3. Genasense Plus Chemotherapy Is Associated With Prolonged Survival in Patients With Relapsed/Refractory CLL Who Achieve Complete Remission
4. Research Study Demonstrates Prolonged Benefit of Fitness Program for Bladder Control & Sexual Function in Women
5. New Data Show TORISEL Improves Progression-Free Survival for Patients With Relapsed/Refractory Mantle Cell Lymphoma
6. Elesclomol Study Shows Significant Improvement in Progression-Free Survival for Chemotherapy-Naive Patients With Metastatic Melanoma
7. Everolimus (RAD001) Significantly Extends Progression-Free Survival in Advanced Kidney Cancer Patients After Failure of Other Targeted Therapy
8. Zevalin(R) Combined With High-Dose Chemotherapy and Autologous Stem-Cell Transplantation (ASCT) Produces High Overall Survival and Progression-Free Survival Rates in Patients With Relapsed Non-Hodgkins Lymphoma
9. Newly Published Phase II Study Shows the Investigational Drug Vandetanib Prolongs Progression-Free Survival in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
10. Isis Announces That OGX-011 Has Shown Overall Survival Advantage in Prostate Cancer Compared to Standard Therapy in a Randomized Phase 2 Study
11. Portable CT Increases Chance of Stroke Survival and Recovery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... , Sept. 17, 2014 An analysis ... regarding patients taking Sovaldi® (sofosbuvir), a new and expensive ... shows that over the last several months (May through ... downward trend in Sovaldi utilization. This suggests another surge ... new therapeutic regimens of similar efficacy and shorter duration ...
(Date:9/17/2014)... Sept. 17, 2014  Aratana Therapeutics, Inc. (NASDAQ: ... on licensing, developing and commercializing innovative biopharmaceutical products ... its public offering of 4,500,000 shares of its common stock ... per share. Aratana has granted the underwriters a ... 675,000 shares of its common stock. ...
(Date:9/17/2014)... , Sept. 17, 2014 Sutro Biopharma, a ... and the biopharmaceutical division of Merck KGaA, Darmstadt, ... in the United States and ... and license agreement to develop antibody drug conjugates (ADCs). ... cytotoxic drug. The antibody is thought to specifically target ...
Breaking Medicine Technology:CVS Health Research Institute Provides First Look at Treatment with New Hepatitis C Therapies 2CVS Health Research Institute Provides First Look at Treatment with New Hepatitis C Therapies 3CVS Health Research Institute Provides First Look at Treatment with New Hepatitis C Therapies 4Aratana Therapeutics, Inc. Announces Pricing of Public Offering 2Sutro Biopharma and Merck KGaA of Darmstadt, Germany, to Partner on Development of Antibody Drug Conjugates 2Sutro Biopharma and Merck KGaA of Darmstadt, Germany, to Partner on Development of Antibody Drug Conjugates 3Sutro Biopharma and Merck KGaA of Darmstadt, Germany, to Partner on Development of Antibody Drug Conjugates 4
(Date:9/17/2014)... September 17, 2014 Representatives with Capitol ... sponsor of Thursday’s Anti-Defamation League Event at the Four Seasons ... we consider it an honor to be a sponsor for ... Pain Institute. , Schocket went on to explain that the ... 600 community leaders and members at the Four Seasons to ...
(Date:9/17/2014)... Texas (PRWEB) September 17, 2014 ... provides key market data on the North America ... millions of US dollars, volume (in units) and ... –, Female Sterilization Devices ... (Tubal Clips and Rings)) , Endometrial ...
(Date:9/17/2014)... Kamut International is pleased to announce that ... Michael Angelo’s new “Made With Organic” ready-made, frozen meals ... ready made, frozen meal. Michael Angelo’s products feature KAMUT® ... products align well with Kamut International’s mission to support ... must be grown certified organic. , The new “Made ...
(Date:9/17/2014)... 17, 2014 Promising new research published ... more light on the potential ability of ketones to ... dementia. The study shows that brain ... caused by impaired glucose uptake and/or utilization, and results ... function. , The study, by the Research Center on ...
(Date:9/17/2014)... Right now no one can say whether yoga provides ... a new article in the Journal of Psychiatric ... scores of people with the condition who practice yoga. ... be a substantial help, but it sometimes carries risks, ... yoga for bipolar disorder," said lead author Lisa Uebelacker, ...
Breaking Medicine News(10 mins):Health News:Capitol Pain Institute Sponsoring an Anti-Defamation League Event & Awards Dinner 2Health News:Gynecological Devices Market in North America (US, Canada & Mexico) to 2020 New Report Available at MarketOptimizer.org 2Health News:Gynecological Devices Market in North America (US, Canada & Mexico) to 2020 New Report Available at MarketOptimizer.org 3Health News:Gynecological Devices Market in North America (US, Canada & Mexico) to 2020 New Report Available at MarketOptimizer.org 4Health News:KAMUT® Brand Wheat Delivers a High Quality Ingredient and Authentic Italian Taste for Michael Angelo’s New Ready-Made Meals featuring Organic Ingredients 2Health News:Journal of Alzheimer's Disease Publishes New Study Suggesting Ketones have Potential to Compensate for Brain Energy Deficit 2Health News:Journal of Alzheimer's Disease Publishes New Study Suggesting Ketones have Potential to Compensate for Brain Energy Deficit 3Health News:Survey finds benefits, risks of yoga for bipolar disorder 2Health News:Survey finds benefits, risks of yoga for bipolar disorder 3
... Point Action Plan on infectious waste control during a ... Monday,s Washington Times (link below), Emergency Preparedness ... issues, such as SARS, have highlighted the vulnerability our ... the area of operational sustainability in a crisis. ...
... visits to doctors and hospitals by people with the disease ... are still reporting new cases of infection with the H1N1 ... in visits to doctors and hospitals by people with the ... health official said Thursday. , "At the national level, ...
... Congress Urged to Support Bill for Bone Health Promotion ... (NOF) in conjunction with the National Coalition for Osteoporosis ... Hill today to engage Congress in an action plan ... lawmakers to sign on to the "Bone Health Promotion ...
... early were more likely to have been victims , , ... when they started menstruating, the more likely black women ... report. , The finding suggests childhood sexual abuse may ... at more than 35,000 women, aged 21 to 69, ...
... Link Services, CaseworkersPHILADELPHIA, May 21 The Field ... the University of Pennsylvania has announced ... Change, Microsoft Corp. and Motorola to pilot the ... private entities, this groundbreaking interoperable, real-time technology system ...
... 2009 Issue Examines Experiences of Denton ... Center DALLAS, May 21 T-System, Inc., the ... departments and urgent care centers, today announced that its Emergency ... in a column entitled "ED Information Systems: A Guideline For ...
Cached Medicine News:Health News:Coalition Calls on Secretary of Health to Make Hospital Emergency Preparedness a Priority 2Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 2Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 3Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 4Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 5Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 6Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 7Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 8Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 9Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 10Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 11Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 12Health News:Swine Flu Outbreak May Be Subsiding, CDC Says 13Health News:The National Coalition for Osteoporosis and Related Bone Diseases Briefed Congress on Action Plan for a National Vision for Bone Health 2Health News:The National Coalition for Osteoporosis and Related Bone Diseases Briefed Congress on Action Plan for a National Vision for Bone Health 3Health News:The National Coalition for Osteoporosis and Related Bone Diseases Briefed Congress on Action Plan for a National Vision for Bone Health 4Health News:The National Coalition for Osteoporosis and Related Bone Diseases Briefed Congress on Action Plan for a National Vision for Bone Health 5Health News:Childhood Sexual Abuse Might Spur Early Periods 2Health News:University of Pennsylvania, Montgomery County Partner on Integrated, Interoperable System Design for Child Welfare 2Health News:The T SystemEV(R) Featured in Journal of Emergency Nursing Paper on Successful EDIS Implementation 2Health News:The T SystemEV(R) Featured in Journal of Emergency Nursing Paper on Successful EDIS Implementation 3
Prostate biopsy transducer....
Multi-frequency, HST, linear transducer with a longer (60mm) footprint. Available with puncture adapter and water path. This transducer incorporates ALOKAs exclusive Hemispheric Sound Technology and ...
... high frequency (13Mhz) ... and superficial imaging. ... Hemispheric Sound Technology ... This multi-frequency transducer ...
... an excellent choice for a ... wide scan angle. With muliple ... designed for a wide view ... versatility of this transducer provides ...
Medicine Products: