Navigation Links
Project Zero Delay Accelerates Drug's Path to Clinical Trial
Date:8/3/2009

HOUSTON and WILMINGTON, Del., Aug. 3 /PRNewswire-FirstCall/ -- A phase I clinical trial enrolled its first patient only two days after U.S. Food and Drug Administration clearance of the experimental drug for a first-in-human cancer trial, a milestone that normally takes three to six months. Investigators from The University of Texas M. D. Anderson Cancer Center and pharmaceutical company AstraZeneca have reported their work in the Journal of Clinical Oncology published online on August 3(rd).

The joint effort, dubbed Project Zero Delay, is part of a strategic collaboration between the two organizations designed to safely accelerate development of new cancer drugs. In many cases that process takes about 12 years and the cost of bringing a new drug to patients has been estimated at around $1.3 billion. [Ref: J. A. DiMasi and H. G. Grabowski, "The Cost of Biopharmaceutical R&D: Is Biotech Different?" Managerial and Decision Economics 28 (2007): 469-479.]

"Project Zero Delay demonstrates how we can shrink the time it takes to bring new drugs to cancer patients," said Robert C. Bast Jr., M.D., vice president for translational research at M. D. Anderson and the paper's senior author. "We need to find out as promptly as possible whether new therapies will help. Zero Delay is a significant step in that direction. Close cooperation allowed us to eliminate unnecessary delays while fully meeting regulatory requirements for scientific and human safety review."

The key to Zero Delay was performing most tasks in parallel instead of sequentially, said lead author Razelle Kurzrock, M.D., professor and chair of M. D. Anderson's Department of Investigational Therapeutics. In addition, tasks usually done after FDA clearance of an Investigational New Drug (IND) application were instead done in advance. No administrati
'/>"/>

SOURCE AstraZeneca
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. The Female Health Company Receives USAID DELIVER PROJECT Order for 5 Million Units
2. Uncontrolled Blood Pressure Highest Among Hispanics, Prompting New Hypertension Project in Miami
3. The Well Project Web Portal Receives Stevie(R) Website of the Year, InfoWorld 100 Award
4. Hospital Launches Landmark Emergency Medicine Project
5. UM Maryland Industrial Partnerships Program Approves 18 Collaborative Research Projects, Worth $4.4 Million, Between University Faculty, State Technology Companies
6. DATATRAK and COResearch to Collaborate on Six Cardiac Safety Projects
7. ACORNs Oncology-focused Contract Research Organization Exceeds Projections
8. Dutch Top Institute Allocates 150 Million Euro to R&D Projects Targeting Early Diagnosis and Treatment of Disease
9. QMed, Inc. Receives 2-Year Extension of Medicare Coordinated Care Demonstration Project by CMS
10. TriLink Awarded a Phase II Grant for a Second Hot Start PCR Project
11. Debiopharm and EPFL Sign Research Project Agreement to Identify Inhibitors of Signalling Pathways Controlling Cell Fate for Cancer Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 2014 Research and Markets has ... Medical X-ray Film Industry Report 2014" report to ... Global And Chinese Medical X-Ray Film Industry ... the current state of the Global medical X-ray film ... The report provides a basic overview of the industry ...
(Date:7/11/2014)... 2014 On Thursday, July ... the Dow Jones Industrial Average finished the day 0.42% lower ... 0.41%. The losses were broad based as eight out of ... Health Care Sector Index ended the day at 711.88, down ... one month. Investor-Edge has initiated coverage on the following equities: ...
(Date:7/11/2014)... , July 11, 2014 Neurelis, Inc. ... ("Biotie") to end the option held by Biotie to ... further development of NRL-1 (intranasal diazepam) for pediatric and ... Over the past year, Biotie has advanced the ... preparation for the pivotal clinical work required for NDA ...
Breaking Medicine Technology:Global and Chinese Medical X-ray Film Industry Report 2014 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3
... BEIJING, June 22, 2011 /PRNewswire-Asia-FirstCall/ -- China Medical ... ), a leading China-based advanced in-vitro diagnostic ("IVD") ... GP Medical Technologies Co., Ltd. ("GP Medical"), has ... An Healthcare Investment Ltd. ("Da An Health") to ...
... Millstone Medical Outsourcing announced today that the ... online inventory management system.  After several months of ... password-protected system used by medical device manufacturers to ... of the enhanced inventory management system include increased ...
Cached Medicine Technology:China Medical Technologies Announces Strategic Collaboration Between its Subsidiary, GP Medical, and Da An Health 2China Medical Technologies Announces Strategic Collaboration Between its Subsidiary, GP Medical, and Da An Health 3Millstone Medical Outsourcing Introduces Advanced Version of Online Inventory Management System 2
(Date:7/14/2014)... News) -- Being physically active in middle age appears ... other types of dementia, suggest the findings from two ... physical exercise at various levels, especially in midlife, is ... Mayo Clinic, said in an Alzheimer,s Association news release. ... yet conclusive. More research is needed to determine the ...
(Date:7/14/2014)... Skin M.D. by ... on Monday, July 14th, located at 45 East ... last all week through Saturday, July 19th, with ... welcomed to attend. The business is owned by ... anti-aging, weight loss services, and sells high-end industry ...
(Date:7/14/2014)... The NIH is giving $8 million ... fund a clinical trial on light-based therapy in mesothelioma ... newly-posted article on the research. , Scientists at ... to enroll 102 pleural mesothelioma study participants ... photosensitizing drug prior to surgery. Then half will have ...
(Date:7/14/2014)... “You've probably heard the expression, 'You ... mean?” This question was posed in an article by ... Medical Group’s blog regarding how people should select what ... . , According to the article, individuals who consume ... a high risk of dehydration and consequent negative health ...
(Date:7/14/2014)... Cabin Chiang Mai, Asia’s leading inpatient addiction treatment centre, ... – a free comprehensive aftercare service for clients who ... they live in the world. , The Cabin firmly ... maintain their recovery after successfully completing primary treatment should ... As a chronic disease, addicts in recovery are always ...
Breaking Medicine News(10 mins):Health News:Staying Active May Help Prevent Dementia 2Health News:The Cosmetic Medic Announces Grand Opening of New Skin M.D., a Physician-Administered Anti-aging, Skincare, and Weight Loss Practice 2Health News:The Cosmetic Medic Announces Grand Opening of New Skin M.D., a Physician-Administered Anti-aging, Skincare, and Weight Loss Practice 3Health News:New Research Could Expand Availability of Light-Based Mesothelioma Therapy, According to Surviving Mesothelioma 2Health News:Drink With Your Mental Health in Mind, Advises an Article by Mental Health America Featured by Western Washington Medical Group 2Health News:The Cabin Chiang Mai Addiction Rehab Launches Industry-leading Aftercare Service 2Health News:The Cabin Chiang Mai Addiction Rehab Launches Industry-leading Aftercare Service 3
... to prevent heart failure, stroke , WEDNESDAY, Nov. ... status as the best first-line treatment in older ... research concludes. , The thiazide-type diuretic chlorthalidone outshone ... an ACE inhibitor and an alpha-receptor blocker -- ...
... to Release Statewide Data , HARRISBURG, Pa., Nov. 18 Pennsylvania ... children and adults living with autism, according to the Pennsylvania Autism ... , "With the release of this report, Pennsylvania becomes the ... prepare to meet the needs of the rapidly growing population of ...
... , CLEVELAND, Nov. 18 Hospice workers have seen patients ... them. Researchers from the Frances Payne Bolton School of Nursing ... Reserve University will study what drives the dying to resolve ... Mary Jo Prince-Paul from nursing and Julie Exline from arts ...
... captures insects, an innovative new device with nano-sized features developed ... in the blood that have broken off from a tumor. ... tumor cells, or CTCs, can provide critical information for examining ... effectiveness of therapies. Metastasis ...
... common surgical painkillers help cancer cells thrive , WEDNESDAY, ... to growing evidence that morphine and other opiate-based painkillers ... , The papers, scheduled to be presented Wednesday at ... preventing opiates from reaching lung cancer cells reduces cancer ...
... ... Organization is asking for nominations for the 2010 Innovations in Healthcare(SM) ABBY ... Event, on April 28, 2010, in Newport Beach, California. At this event, ... of the toughest problems facing healthcare today, and three will take home ...
Cached Medicine News:Health News:Diuretics Still Best Treatment for High Blood Pressure 2Health News:PA Governor Rendell: New Report Shows Demand for Autism Services will Continue to Rise 2Health News:Research Collaboration Focuses on Unfinished Business at the End of Life 2Health News:UCLA researchers create 'fly paper' to capture circulating cancer cells 2Health News:UCLA researchers create 'fly paper' to capture circulating cancer cells 3Health News:Morphine May Help Tumors Spread in Cancer Patients 2Health News:Nominate Your Favorite Innovative Healthcare Company for the 2010 ABBY Awards 2Health News:Nominate Your Favorite Innovative Healthcare Company for the 2010 ABBY Awards 3Health News:Nominate Your Favorite Innovative Healthcare Company for the 2010 ABBY Awards 4
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: