Navigation Links
Progesterone Therapy and Preterm Birth: More Evidence Helps Identify Women Who Can Benefit
Date:8/19/2007

WHITE PLAINS, N.Y., AUG. 2 /PRNewswire-USNewswire/ -- Two major studies published today in The New England Journal of Medicine can help doctors better identify pregnant women at risk for preterm delivery who can benefit from progesterone treatment, the March of Dimes Foundation said today.

In one large multi-center trial led by Eduardo B. Fonseca, M.D., women with short cervix (most of whom had no prior history of preterm birth) who received progesterone suppository treatment between 24 and 34 weeks gestation had a greatly reduced rate of preterm birth.

Another large multi-center trial led by Dwight J. Rouse, M.D., found that weekly injections of 17P (17 alpha-hydroxyprogesterone caproate, a derivative of progesterone) between 16 and 35 weeks gestation did not reduce the rate of preterm birth among women carrying twins.

"Premature birth is a growing problem in the United States and a leading killer of newborns," said Michael Katz, senior vice president for Research and Global Programs of the March of Dimes. "With this new information, physicians will have a better idea of how to identify those women who are most likely to benefit from progesterone treatment from those who are not."

Dr. Katz noted that pathways to preterm birth may differ substantially between singleton and twin gestations. For example, progesterone may be more effective against some pathway that does not involve the uterine over- distention seen in twin pregnancy.

"We need more research into the underlying causes of prematurity to help women with other risk factors," Dr. Katz said.

In previous studies (Meis et al., NEJM, 2003;348:2379-85; da Fonseca et al., Am J Ob Gyny, 2003;188:419-24), the benefit of progesterone was seen in women with singleton pregnancies and a documented history of a previous spontaneous preterm birth. These study results led to a Committee Opinion issued by the American College of Obstetricians and Gynecologists on the use of progest
'/>"/>

SOURCE March of Dimes Foundation

Copyright©2007 PR Newswire.

1

GOOD

Page: 1 2

Related medicine technology :

1. Columbia Laboratories Reports Preliminary Findings from the Ongoing Data Analysis of the Phase III Clinical Study of PROCHIEVE 8% (progesterone gel) to Prevent Preterm Birth
2. Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
3. Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
4. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
5. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
6. YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds to the EGF Receptor and Potentiates Radiotherapy
7. Response Genetics Announces Publication of a Phase III Clinical Trial Demonstrating That Low Levels of ERCC-1 Help to Predict Likelihood of Response to Cisplatin-Based Therapy in Lung Cancer
8. New Phase 3 Study Published in The Lancet Evaluates Efficacy and Safety of Prezista/Ritonavir vs. Kaletra as Part of HIV Combination Therapy in Treatment-Experienced Adults With HIV
9. Lexicon Develops Antibodies That Lower Triglycerides and Cholesterol as Potential New Therapy for Heart Disease
10. Studies of Drug Resistance May Lead to Individual Therapy for Rare Cancers
11. Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... , 22. Mai 2013 Kepner-Tregoe ... Beratung, gab heute bekannt, dass der Veteran ... , zum Hauptgeschäftsführer ernannt wurde. Geraghty,s ... Industriebereich wo er zahlreiche Führungspositionen bei Fertigungsunternehmen ... Baxter an, der als Kepner-Tregoe Hauptgeschäftsführer gedient ...
(Date:5/22/2013)... 2013 Z-Medica, a leading developer and marketer ... first-ever line of products designed to meet the unique ... ® EMS 4x4 Dressing, QuikClot ® EMS ... Gauze™, all custom-designed to help responders stop bleeding fast ... to a hospital or trauma center. The line includes ...
(Date:5/22/2013)... May 22, 2013  MGT Capital Investments, Inc. (NYSE ... at the Second Annual Marcum LLP MicroCap Conference on ... City at the Grand Hyatt Hotel.  ... Officer, will update investors and answer questions. ... presentation is scheduled to begin at 9:30 a.m. EDT.  ...
Breaking Medicine Technology:Kepner-Tregoe, Inc. befördert Chris Geraghty zum Hauptgeschäftsführer 2Kepner-Tregoe, Inc. befördert Chris Geraghty zum Hauptgeschäftsführer 3Z-Medica Launches New Line of Hemostatic Agents for use in Emergency Medical Services 2MGT Capital Investments, Inc. To Present At The Second Annual Marcum LLP MicroCap Conference 2MGT Capital Investments, Inc. To Present At The Second Annual Marcum LLP MicroCap Conference 3MGT Capital Investments, Inc. To Present At The Second Annual Marcum LLP MicroCap Conference 4
(Date:5/22/2013)... Thompson HealthDay Reporter , , WEDNESDAY, May 22 ... back pain are more likely to attempt suicide, whether ... psychiatric condition, according to a new study. "Clinicians ... be aware they are at increased risk of suicide," ... Serious Mental Illness Treatment Resource and Evaluation Center in ...
(Date:5/22/2013)... Successful Therapy for Parents program, ... in the Silver Lake community of Los Angeles ... progression to existing Parents and Couples counseling programs. ... therapy has always been suggested, but now it's ... specializes in all aspects of relationships ...
(Date:5/22/2013)... Bodybuilding.com is giving back to those who have ... be donating $1 from EVERY purchase made between 12:01am – ... grateful for the men and women who have served our ... founder of Bodybuilding.com. “It’s an honor to give back to ... USA is an amazing organization that supports our nation’s veterans ...
(Date:5/22/2013)... According to a May 14, 2013 US ... for Breast Cancer Surgery,” modern medical technology has given women ... disease in a whole new light. Since the new approach ... breast cancer and mastectomies with greater hope for ... introduction of plastic surgery to oncology, women had little choice ...
(Date:5/22/2013)... 22, 2013 Today, Zane Benefits, Inc. ... Insurance Exchange . Zane Benefits, which provides comprehensive and ... the leader in defined contribution plans and ... Benefits’ website, beginning in 2014 as part of the ... and small businesses will become available through new state ...
Breaking Medicine News(10 mins):Health News:Migraine, Chronic Back Pain Tied to Higher Suicide Risk 2Health News:Migraine, Chronic Back Pain Tied to Higher Suicide Risk 3Health News:Patricia O’Laughlin Psychotherapy of Los Angeles Now Seeing Adults, Teens and Young Children 2Health News:In the Spirit of Memorial Day, Bodybuilding.com is Donating a Portion of Their Sales to Hire Heroes 2Health News:Breast Augmentation – New Option for Breast Cancer Surgeries 2Health News:Zane Benefits Publishes New Information on Alabama Health Insurance Exchange 2Health News:Zane Benefits Publishes New Information on Alabama Health Insurance Exchange 3
... MONDAY, Dec. 5 (HealthDay News) -- There,s been a large increase ... States since 2002, a trend that may help ease concerns about ... analyzed national data and found that the number of RNs aged ... fell to fewer than 110,000 by 1991 and remained low for ...
... University of Kentucky researchers recently received a $225,000 grant ... The grant gives the team $225,000 for the ... that could total $675,000. It is funded by the ... Rural Cancer Prevention Center. Published studies have shown ...
... By Serena Gordon HealthDay Reporter , MONDAY, Dec. ... with asthma is currently using a preventive medication, according to ... percent of kids during the late 1980s. Preventive ... up, and guidelines from the U.S. National Asthma Education and ...
... -- Teenagers with autism who also have epilepsy often ... The combination means that certain behaviors common among autistic ... of their faces -- could increase their risk for ... 14 percent of children with epilepsy, the rate jumps ...
... and non-obese children found that low vitamin D levels are ... risk factors for type 2 diabetes. This study was accepted ... Endocrinology & Metabolism (JCEM). High rates of vitamin ... studies have linked low vitamin D levels to cardiovascular disease ...
... , SATURDAY, Dec. 3 (HealthDay News) -- Seizures ... during menstruation or ovulation, researchers have found. ... at the University of California, Irvine, examined the trend ... among a group of women aged 19 to 50. ...
Cached Medicine News:Health News:Good News for Those Worried About U.S. Nursing Shortage 2Health News:University of Kentucky researchers awarded CDC grant to study cancer survival in Appalachia 2Health News:More Children Using Preventive Asthma Drugs: Study 2Health News:More Children Using Preventive Asthma Drugs: Study 3Health News:Low vitamin D levels may contribute to development of Type 2 diabetes 2Health News:Epileptic Seizures May Worsen During Menstrual Cycle 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: