red meat increased the risk by 38 percent. The researchers also found
that eating four or more servings of vegetables daily was associated
with a 32 percent reduction in risk, consuming high amounts of lean
protein was associated with a 15 percent risk reduction, and that
regular, moderate alcohol consumption (no more than two drinks a day)
was associated with a 38 percent decline in BPH risk.
-- Obesity is associated with an 80 percent increase in the risk of
high-grade, aggressive prostate cancer. What's more, in men who are
at high risk of prostate cancer because of prostate cancer occurring in
a first-degree relative, the distribution of body fat may also
contribute to increased prostate-cancer risk. "Apple-shaped"
men, who store fat in the abdominal area, have a nearly two-fold
increased risk of both low- and high-grade prostate cancer. The
mechanisms behind the link between obesity and the most aggressive,
fatal form of prostate cancer are believed to involve both steroid
hormones and systemic inflammation. "Obesity is a massive
inflammatory condition," Kristal said. "It also increases
levels of circulating estrogens and growth factors that promote cell
-- A high-calcium diet, calcium supplements and antacids may increase the
risk of advanced prostate cancer. In men who consume more than 1,200 mg
per day (equivalent to four or more glasses of milk), the risk of
aggressive cancer increases by more than 100 percent. High intake of
calcium suppresses blood levels of the active form of vitamin D, a
hormone that may protect against prostate cancer.
-- Obese men who are diagnosed with prostate cancer have more than
two-and-a-half times the risk of dying from the disease a
|SOURCE Fred Hutchinson Cancer Research Center|
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