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Pressure BioSciences, Inc. and Target Discovery, Inc. Expand Strategic License Agreement and Collaboration Supporting TDI's Planned Offering of Personalized Medicine Clinical Diagnostic Services
Date:4/23/2012

proved patient care and health-economic outcomes.  Our first area of application focus is in ovarian cancer, where over 22,000 women are diagnosed annually in the USA with this fast-moving disease, and over two-thirds of these new patients could be helped dramatically by the introduction of reliable treatment selection guidance diagnostic information."

"Membrane proteins play key biological roles in cancer, in drug resistance, and in viral infections, yet until now scientists have been virtually unable to use this important class of biomarkers for diagnostic and prognostic testing," commented Dr. Luke V. Schneider, TDI's Chief Scientific Officer. "These proteins are tightly bound within the cell membrane, making them very difficult to extract and recover for scientific study.  The extraction of membrane proteins from tissue samples typically requires the use of aggressive physical and chemical methods that yield useless protein fragments, often in solutions that are completely incompatible for laboratory testing.  Consequently, although membrane proteins and their isoforms play vital roles in human health and disease, they have never been conveniently available for use as disease biomarkers."

Mr. Richard T. Schumacher, CEO of PBI, remarked: "The innovative scientific team at TDI has vaulted important anticipated applications for PCT forward into near-term realities.  The power and impact of TDI's isoform-focused technologies and their promise in opening a new era in personalized medicine diagnostics for cancer treatment is dramatic and inspiring.  We are excited that PBI's patented PCT Platform will provide the sample-processing foundation upon which many of TDI's next generation clinical laboratory testing services will be based, and we look forward to supporting our colleagues at TDI with our continued collaboration, and by fulfilling their expected PCT Platform instrument and consumables needs."

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