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Pressure BioSciences, Inc. and Target Discovery, Inc. Expand Strategic License Agreement and Collaboration Supporting TDI's Planned Offering of Personalized Medicine Clinical Diagnostic Services
Date:4/23/2012

SOUTH EASTON, Mass., April 23, 2012 /PRNewswire/ -- Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI") and Target Discovery, Inc. ("TDI"), (together "the companies"), today announced the signing of expanded strategic technology license and supply agreements (the "Agreements"). Under these agreements, TDI now has the right to use PBI's patented and enabling Pressure Cycling Technology ("PCT") Platform for their planned entry into the clinical diagnostics testing market. The planned commercial diagnostic services will initially target what the companies believe are critical, unmet needs in treatment selection guidance for ovarian cancer.  Until now, PBI's PCT Platform has been available on a "research-use-only" basis.

In 2010, the companies announced a collaboration to combine PBI's PCT Platform with TDI's proprietary reagents to enable the extraction of membrane protein biomarkers from human tissue.  Such biomarkers include specific modified proteins ("isoforms") that have heretofore been very difficult to extract from tissue in a form suitable for diagnostic testing.  The companies believe that the ability to rapidly extract and recover diagnostically and commercially useable protein isoforms from cell membranes is unique to PCT and the TDI reagents, and that this capability positions the companies with game-changing abilities to exploit this critical class of membrane proteins as diagnostic biomarkers.

Mr. Jeffrey N. Peterson, CEO of TDI, and a director of PBI, said: "We are very pleased with the progress and outcomes achieved in our on-going multi-year collaboration with PBI. We believe that the PCT Platform, in combination with TDI's proprietary reagents, provides reliable access to this important class of protein biomarkers for life sciences R&D.  We further believe that variations measured in these protein isoforms are expected to translate into important commercial applications, and desperately needed breakthroughs in im
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SOURCE Pressure BioSciences, Inc.
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