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Prescient Medical, Inc. Acquires New Technology to Detect Inflammation in Coronary Blood Vessels
Date:11/13/2007

Time Resolved Light Induced Fluorescence Spectroscopy (TR-LIFS) to be Combined with Other PMI Diagnostic Technologies to Help Prevent Deaths

Related to Heart Attacks

DOYLESTOWN, Pa., Nov. 13 /PRNewswire/ -- Prescient Medical, Inc., a privately held medical device company dedicated to reducing deaths from heart attacks, announces the acquisition of a new technology that identifies and quantifies metabolic activity and inflammation in human artery tissue by measuring the time it takes for light to dissipate after the tissue has been excited with ultra-short light pulses.

The new technique, called Time Resolved Light Induced Fluorescence Spectroscopy (TR-LIFS), exploits the phenomenon that bi-products of metabolic activity behave differently than surrounding tissue. In TR-LIFS, a short light pulse (picoseconds) is used to excite the tissue, and then the resulting light that emanates from the tissue is monitored over a brief time span (several nanoseconds). This technology has been verified by several research groups to accurately detect inflammation in human tissue in vitro and in vivo.

Arterial plaques are associated with an array of biochemical, functional, and structural changes that can be readily identified with optical techniques. Another Prescient Medical technology, Raman spectroscopy, has been proven to provide exquisite compositional detail, in vivo, of arterial wall constituents and will be entering clinical trials early next year. By combining TR-LIFS with Raman spectroscopy, Prescient's burgeoning arsenal of tools to assist physicians in assessing plaque vulnerability is buttressed with a formidable new diagnostic weapon.

"We believe the development of TR-LIFS technology into a diagnostic product will provide another valuable tool in the fight against heart disease," said Patricia Scheller, Prescient's chief executive officer. "Since 80 percent of all heart attacks are caused by soft plaques tha
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SOURCE Prescient Medical, Inc.
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