Navigation Links
Preliminary PI-88 Phase 2 Prostate Cancer Results to be Presented at the American Society for Clinical Oncology (ASCO) 2008 Genitourinary Cancer Symposium
Date:2/13/2008

onsidered typical for that drug.

Two patients are continuing with PI-88 treatment after successfully completing the combination treatment. Specifically, one patient has remained on the study after 74 weeks while the other remains after 40 weeks.

Dr. James Garner, Progen's Vice President of Clinical and Medical Affairs commented, "We are encouraged by the efficacy trends demonstrated in this patient population. Prostate cancer is an indication with continuing high unmet medical need and there is a clear demand for new therapies here. The febrile neutropaenia rates seen in this study are difficult to interpret, given that this small investigator-led study lacks a control group. We have not seen evidence of febrile neutropaenia in our previous clinical experience combining PI-88 with Taxotere(R), and there is no biological reason to suspect that the combination might result in increased toxicity. We will discuss this unexpected finding with our clinical and scientific advisors to determine the appropriate next steps in terms of development."

Justus Homburg, Progen's Chief Executive Officer continued, "Prostate cancer continues to be an indication we are interested to explore more, therefore, we will continue to analyze the results and do additional work to establish how best to combine PI-88 with existing therapies in this indication. In the interim, our phase 3 study in the adjuvant hepatocellular carcinoma setting is expected to begin recruitment shortly. We do not anticipate any concern regarding febrile neutropaenia in this phase 3 study, as it is a monotherapy study in a patient population with which we already have substantial clinical data."

About Progen: Progen Pharmaceuticals Limited is an Australian-based globally focused biotechnology company committed to the discovery, development and commercialization of small molecule therapeutics primarily for the treatment of cancer.

About PI-88: PI-88 is one of a new class of multi-ta
'/>"/>

SOURCE Progen Pharmaceuticals Limited
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
2. Genomic Health Announces Preliminary Results From a Study of Oncotype DX(TM) in Node-Positive Breast Cancer Patients
3. Preliminary Results of Randomized Pilot Study Show Comparable Efficacy for OrbusNeichs Genous(TM) Bio-engineered R Stent(TM) and Boston Scientifics Taxus(R) Stent in Patients at High Risk of Restenosis
4. Sunesis Pharmaceuticals Reports Preliminary SNS-595 Activity in Ovarian Cancer Clinical Trial at AACR-NCI-EORTC International Conference
5. Pharmion and MethylGene Report Preliminary MGCD0103 Clinical Data at the 2007 AACR-NCI-EORTC International Conference
6. Keryx Biopharmaceuticals, Inc. Announces Positive Preliminary Phase 2 Data on KRX-0401 in Patients with Chemo-Insensitive Rare Sarcoma
7. Vion Pharmaceuticals To Present Preliminary Data on its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) at the American Society of Hematology Meeting
8. Pixantrone Versus Doxorubicin in CHOP-R Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Preliminary Results Presented at American Society of Hematology (ASH) Annual Meeting
9. Anthera Announces Preliminary Positive Results From Once-Daily A-002 Phase II Cardiovascular Trial
10. Morria Biopharmaceuticals Plc Announces Preliminary Safety and Tolerability Results From Its Phase I Clinical Study of MRX-4 in Allergic Rhinitis Patients
11. A Functional Immune System Can Be Derived From Embryonic Stem Cells, Preliminary Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... , Dec. 23, 2014 ResMed (NYSE: ... patent infringement action against Chinese medical device manufacturer BMC Medical ... ruled today that BMC,s masks listed below infringe ResMed,s patents, ... selling these masks in the United States ... N2 nasal mask , Willow nasal pillows mask ...
(Date:12/24/2014)...   Synageva BioPharma Corp. (NASDAQ: ... products for rare disorders, today announced validation by ... Authorization Application (MAA) for sebelipase alfa for LAL ... for accelerated assessment, which has the potential to ... The MAA, and the Biologics License Application ...
(Date:12/24/2014)... DALLAS , Dec. 23, 2014  Lockton ... operation of Lockton Companies, announced the addition of ... Foerster will join Lockton Dunning,s Pharmacy Consulting team, ... years of relevant industry experience to the position.  ... Managed Market Sales at Diplomat Specialty Pharmacy, where ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3Kim Foerster Joins Lockton Companies 2
... NEW YORK, Sept. 26, 2011 Reportlinker.com ... is available in its catalogue: ... 2011-2021 http://www.reportlinker.com/p0629356/Pharmaceutical-Contract-Manufacturing-World-Market-Outlook-2011-2021.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pharmaceutical ... How will the pharma contract manufacturing ...
... PRNewswire/ -- Cell Therapeutics, Inc. (CTI) (NASDAQ and MTA: ... M.D., F.A.C.P., to its Board of Directors as a ... of Directors to nine members, seven of whom are ... Vice President and Chief of Medical Affairs at UnitedHealth ...
Cached Medicine Technology:Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 2Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 3Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 4Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 5Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 6Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 7Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 8Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 9Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 10Pharmaceutical Contract Manufacturing: World Market Outlook 2011-2021 11Reed V. Tuckson, M.D., Executive Vice President and Chief of Medical Affairs at UnitedHealth Group, Joins Board of Directors of Cell Therapeutics, Inc. (CTI) 2Reed V. Tuckson, M.D., Executive Vice President and Chief of Medical Affairs at UnitedHealth Group, Joins Board of Directors of Cell Therapeutics, Inc. (CTI) 3
(Date:12/25/2014)... Product liability lawsuits filed in the ... http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal court, ... in the U.S. District Court, Northern District of Ohio ... conference on January 7, 2015, at the Paul G. ... Palm Beach, Florida. The Conference is scheduled to begin ...
(Date:12/25/2014)... December 26, 2014 Recently, Dylan Queen, ... has excitedly released its collection of discounted prom dresses, ... Percy, a senior spokesman of the company, the promotion ... this promotion is to expand the UK market. , ... several different colors, lengths, and styles: A-line strapless, empire ...
(Date:12/25/2014)... BambooFlooringChina.com sells many bamboo products and the ... the company announces big discounts on its bamboo ... , BambooFlooringChina.com is the world’s leader in bamboo flooring. ... until Jan. 20, 2015. , The bamboo mats are ... natural thread. All the bamboo strips for the mats ...
(Date:12/25/2014)... Recently, LunaDress.co.uk has updated its blog to provide ... Now, all of the models at LunaDress.co.uk come with big discounts, ... the wedding veil can turn out to be a most exciting ... veil can always bring surprise to a wedding. On the updated ... choose veils for a big day . , Going out ...
(Date:12/25/2014)... THURSDAY, Dec. 25, 2014 (HealthDay News) -- Overeating is common ... you eat in moderation, an expert says. "Don,t arrive ... up calories if you know you,ll be attending a party, ... Jill Ashbey-Pejoves, lead dietitian at Northern Westchester Hospital in Mount ... better to eat healthy during the day and even to ...
Breaking Medicine News(10 mins):Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2
... Employment Sectors , ... Brookfield, Wisconsin (PRWEB) November 26, ... looking for help in managing their money. One place they may ... employers conducted by the International Foundation of Employee Benefit Plans ...
... not work unless personal accountability is an integral part. ... instructor, just released his new book, Change Made Easy ... Mental Health, published by Advantage Books in Orlando, Florida. ... without all the hype and product promotions. It is ...
... RARITAN, N.J., Nov. 26 Johnson & Johnson Pharmaceutical ... received a Complete Response letter from the U.S. Food ... (NDA) for ceftobiprole for the treatment of complicated skin ... , , The FDA ...
... Inc.,(NYSE: NUS ) today announced that it will ... 4, 2008, at the Grand Hyatt Hotel,in New York City. ... operational results and introduce 2009 plans. , ... be accessed by visiting the investor,relations section of the company,s ...
... more than 20,000 people will,visit the emergency room due to ... is a odorless and colorless gas which will kill approximately,500 ... Aurora Health Care and the American ... poisoning this holiday season. The,winter months see a drastic increase ...
... With economic pressures on the rise,consumers are looking for ways ... they can for their pets. In the midst of ... visits and,spending for recommended procedures. , ... to become economic casualties.,Through a not-for-profit pet health resource - ...
Cached Medicine News:Health News:43% of Employers Offer Financial Education Programs for Their Employees 2Health News:43% of Employers Offer Financial Education Programs for Their Employees 3Health News:43% of Employers Offer Financial Education Programs for Their Employees 4Health News:Lt. Col. Weinstein, New Book: Universal Health Care Will Not Work Unless 2Health News:Lt. Col. Weinstein, New Book: Universal Health Care Will Not Work Unless 3Health News:Lt. Col. Weinstein, New Book: Universal Health Care Will Not Work Unless 4Health News:FDA Issues Complete Response Letter for Ceftobiprole for Treatment of Complicated Skin Infections 2Health News:FDA Issues Complete Response Letter for Ceftobiprole for Treatment of Complicated Skin Infections 3Health News:'Tis the Season for Carbon Monoxide 2Health News:As Consumers Put a Leash on Spending, Experts Caution Against Being 'Penny Wise and Pound Foolish' with Their Pets 2Health News:As Consumers Put a Leash on Spending, Experts Caution Against Being 'Penny Wise and Pound Foolish' with Their Pets 3Health News:As Consumers Put a Leash on Spending, Experts Caution Against Being 'Penny Wise and Pound Foolish' with Their Pets 4
... Signature is a state of the ... integrates blood, sterile body fluid and ... microbiology workstation with comprehensive capabilities. It ... and where expanded flexibility in operating ...
The Vitek 2 - XL is a fully automated bacteriology system that performs bacterial identification and susceptibility testing analysis using a standard inoculum. It detects resistance and helps combat ...
IDS Rapid STR, a microbial identification system....
IDS Rapid NF Plus, a microbial identification system....
Medicine Products: