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Preclinical Study Examines Use of nContact's Technology in Enabling a Percutaneous Device Approach to Epicardial Ablation
Date:2/23/2012

MORRISVILLE, N.C., Feb. 23, 2012 /PRNewswire/ -- nContact, Inc., the leading innovator in epicardial ablation devices, today announced that a new preclinical study examines a unique minimally invasive percutaneous approach to accessing the heart that may enable electrophysiologists (EPs) to perform epicardial ablation for ventricular tachycardia (VT). The study was published in the February 2012 issue of The Journal of Innovations in Cardiac Rhythm Management.

In the study, "Creating Transmural, Linear Epicardial Ablation Lesions via a Non-surgical, Percutaneous, Subxyphoid, Electrogram-guided Approach," researchers sought to modify an existing epicardial ablation device's (nContact's EPi-Sense® Guided Coagulation Device with VisiTrax®) transdiaphragmatic approach to a percutaneous subxyphoid (below the sternum) approach that could enable epicardial ablation without requiring a more invasive surgical access. The EPi-Sense® system has been used clinically in Europe for the treatment of atrial fibrillation and investigators in this study suggest it may also be suitable for the treatment of sinus tachycardia and challenging VT. 

"In this study, we examined for the first time a truly minimally invasive, 'incisionless' approach to performing epicardial ablation. Clinical experience has shown that VT and other arrhythmias originating on the epicardial aspect of the heart may not respond to endocardial ablation, suggesting the need for less invasive tools designed to create lesions on the epicardium," said lead investigator Miguel Valderrabano, MD, FACC of The Methodist Hospital, Houston, TX. "While further studies are needed on the applicability of this technique in clinical electrophysiology, our findings suggest it may expand the capabilities of EP-guided ablation and offer promising clinical utility in addressing VT."

For this preclinical study, researchers performed epicardial ablation on six pigs with a
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