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Preclinical Data on Lead MEK Inhibitor, RDEA119, to be Presented at the 2007 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
Date:10/8/2007

- RDEA119: A Potent and Selective MEK inhibitor with Favorable In Vitro and

In Vivo Anti-Tumor Properties -

CARLSBAD, Calif., Oct. 8 /PRNewswire-FirstCall/ -- Ardea Biosciences, Inc. (Pink Sheets: ARDC), a company focused on the discovery and development of small-molecule therapeutics for the treatment of viral diseases, cancer and inflammatory diseases, today announced that preclinical data on its lead MEK inhibitor, RDEA119, will be presented at the American Association of Cancer Research (AACR), National Cancer Institute (NCI) and European Organization for Research and Treatment of Cancer (EORTC) International Conference on Molecular Targets and Cancer Therapeutics in San Francisco, October 22-26, 2007. The abstract entitled "RDEA119: A Potent and Highly Selective MEK Inhibitor for the Treatment of Cancer," will be presented on October 24, 2007 at 12:30 p.m. Pacific Standard Time.

Event: AACR-NCI-EORTC International Conference on Molecular Targets

and Cancer Therapeutics

Title: RDEA119: A Potent and Highly Selective MEK Inhibitor for the

Treatment of Cancer

Date: Wednesday, October 24, 2007

Time: 12:30 - 2:30 p.m. and 5:30 - 7:30 p.m. Pacific Standard Time

Location: Poster Session B -- Exhibit Hall, First Floor, Moscone

Convention Center West

About RDEA119 and Ardea's MEK Inhibitor Program

Ardea Biosciences has a broad-based R&D program focused on the design and development of small-molecule inhibitors of mitogen-activated ERK kinase, or MEK, for the treatment of cancer and inflammatory diseases. Since defects in the RAS/RAF/MEK/ERK signaling pathway are closely associated with the development of human tumors, such as melanoma, colon, lung and thyroid cancers, inhibiting MEK signaling has promise in the treatment of many types of cancer. MEK inhibitors may also play an important role in the potential treatment of inflam
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SOURCE Ardea Biosciences, Inc.
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