Navigation Links
Precision Therapeutics Presents Clinical Study Emphasizing the Role of ChemoFx® in Directing Chemotherapy in Gynecological Cancers
Date:6/6/2011

PITTSBURGH, June 6, 2011 /PRNewswire/ -- Dr. Bradley Monk of the Creighton University School of Medicine presented a new gynecologic cancer study at the 2011 American Society of Clinical Oncology (ASCO) Annual Symposium, June 5th in Chicago, Illinois.  The study, titled, Acquired Drug Resistance in Gynecologic Cancer Detected by an In Vitro Assay, begins to answer the question of whether ChemoFx® Drug Response Marker test results taken in the primary setting can be utilized for predicting chemotherapeutic response in the recurrent setting.

To evaluate changes in chemosensitivity, ChemoFx® testing was performed on 30 patient specimens in both the primary and recurrent setting.  Test results were then analyzed to observe the development of resistance to commonly-utilized treatments for recurrent gynecologic cancers.  A significant shift towards resistance was found in the agents carboplatin and paclitaxel, but a significant shift was not observed in other agents studied.  The shift in response for carboplatin and paclitaxel may be attributed to a combination of the two agents being a NCCN® Guideline-recommended first-line therapy for primary ovarian cancer patients.

Though this shift towards resistance should be taken into consideration if a metastatic specimen is available for reanalysis, ChemoFx® results for agents not commonly used as first-line therapies were consistent in both the primary and recurrent setting.  This supports the utility of marker results obtained in the primary setting for assisting in treatment decisions when tissue is not available at the time of recurrence.

"This study suggests that ChemoFx® is able to parallel the clinical portion of ovarian cancer treatment that is associated with predicting which drugs are active in targeting optimal chemotherapy," says Dr. Bradley Monk, Professor in the division of Gynecological Oncology at Creighton University School of Medicine. "Over 1 million cases per year in the U.S. alone are treated with chemotherapy through a 'trial and error' based approach and targeting which agents are most likely to predict response is a major stride in personalizing medicine."

About Precision Therapeutics

Precision Therapeutics, a leading life-science company based in Pittsburgh, Pennsylvania, is dedicated to personalized cancer care.  Precision offers a portfolio of products developed to help guide physicians and patients with difficult clinical decisions throughout the cancer care continuum.

Precision's state of the art bioinformatics combined with the analysis of the live molecular, proteomic and genomic activity of each patient's cancer offer an innovative foundation for further development and commercialization of novel predictive markers for cancer therapy. 

About ChemoFx®

Precision's first commercial test, ChemoFx®, is a proprietary drug response marker which measures an individual's malignant tumor response to a range of standard therapeutic alternatives under consideration by a physician. For more information, please visit www.precisiontherapeutics.com, or www.chemofx.com.


'/>"/>
SOURCE Precision Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. 96-Well Filtration Plate From Varian, Inc. Improves Sensitivity and Precision for Trace Bio-Analysis by LC/MS
2. Applied Precision Announces New Products for Life Sciences Microscopy at the 110th American Society for Microbiology Meeting in San Diego, CA, May 23-26th.
3. Precision Bearing Technologies Featured at Atlantic Design & Manufacturing Show
4. Precision Therapeutics, Inc. Named to Pittsburgh Business Times 2010 Top 100
5. Applied Precisions Mobile Imaging Lab Hits the Road for a Cross-Country Journey
6. Clinical Experts Detail How They Use Varians TrueBeam™ Technology to Improve the Precision and Speed of Cancer Treatments
7. Precision Therapeutics President and CEO Sean McDonald Recognized as a Leading Business Executive and Recipient of 2010 Pacesetters Award
8. Applied Precision Installs a Record Four New DeltaVision OMX Super-Resolution Imaging Systems in Eight Weeks
9. Exempla Saint Joseph Hospital Commences Treating Cancer Patients Using New TrueBeam™ System for High-Precision Image-Guided Radiotherapy and Radiosurgery
10. Abbott Diabetes Care Announces Recall of Certain Lots of Precision Xtra®, Precision Xceed Pro®, MediSense® Optium™, Optium™, OptiumEZ and ReliOn® Ultima Blood Glucose Test Strips in the United States and Puerto Rico
11. Applied Precision Scientific Team to Present 3D-SIM Paper at BiOS in San Francisco
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... 2017  The particle counters market is projected ... USD 275.9 million in 2016, at a CAGR ... http://www.reportlinker.com/p04718602-summary/view-report.html The growing pharmaceutical ... and growth in manufacturing industries in emerging nations ... particle counters. On the other hand, technical limitations ...
(Date:2/23/2017)... 23, 2017 Visiomed, the French leader ... 1997, is changing the landscape of healthcare with ... with pro-active, custom-made solutions. Recognizing the rising demand ... affordable healthcare without walls, Visiomed has launched BewellConnect, ... with healthcare professionals that is empowering the lives ...
(Date:2/23/2017)... 23, 2017  Cogentix Medical, Inc. (NASDAQ: CGNT), a ... proprietary products for the urology market, will release financial ... December 31, 2016 before the market open on Thursday, ... host a conference call and webcast to discuss its ... 2017 at 11:00 a.m. Eastern Time (10:00 a.m. Central ...
Breaking Medicine Technology:
(Date:2/24/2017)... ... February 24, 2017 , ... Dr. Ronald E. Hawkins, vice ... appointment of Peter A. Bell, DO, MBA, HPF, FACOEP-dist., FACEP, as the new ... 10. Dr. Bell comes to Liberty from the Ohio University Heritage College of ...
(Date:2/24/2017)... ... February 24, 2017 , ... ... it is so critically important that we all are aware of our options ... Mediaplanet is proud to announce the launch of its newest edition of "Vision ...
(Date:2/24/2017)... Aliso Viejo, CA (PRWEB) , ... February 24, 2017 , ... ... within Final Cut Pro X . Users have total control over position, rotation, ... amount, and more all within Final Cut Pro X. , With ProGlass Prism users ...
(Date:2/24/2017)... ... 24, 2017 , ... The International Association of Eating Disorders Professionals (iaedp) announces ... See” body image mannequin art competition. Selected from 15 submissions from around the nation, ... at the 31st annual iaedp Symposium, March 22 – 26 in Las Vegas. , ...
(Date:2/24/2017)... , ... February 24, 2017 , ... ... services, which specializes in thought leadership , media relations, social media, content ... services that will be powered through Act-On, an intuitive marketing automation platform. , ...
Breaking Medicine News(10 mins):