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Prasugrel Significantly Reduced New or Recurrent Heart Attacks in Both Acute and Longer-Term Settings Following PCI, Compared with Clopidogrel
Date:9/3/2008

1. Type 1: Spontaneous myocardial infarction related to ischemia due to a primary coronary event

Type 2: Myocardial infarction secondary to ischemia due to either increased oxygen demand of the heart or decreased blood supply

Type 4/Type 5: Myocardial infarction associated with PCI/CABG

Thygesen K et al. Universal Definition of Myocardial Infarction. EHJ(2007);28:2525-2538 http://www.escardio.org/guidelines-surveys/esc- guidelines/GuidelinesDocuments/guidelines-universal-MI-FT.pdf. Accessed August 13, 2008.

2. Wiviott, S, Braunwald, E, et al. Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes. New England Journal of Medicine. November 2007;357:2001-15.

3. World Health Organization. The Atlas of Heart Disease and Stroke - Deaths from Coronary Heart Disease. http://www.who.int/cardiovascular_diseases/en/cvd_atlas_14_deathHD.pdf. Accessed August 13, 2008.

4 .American Heart Association. Heart Disease and Stroke Statistics - 2008 Update. http://www.americanheart.org/downloadable/heart/1200082005246HS_Stats%20200 8.f inal.pdf. Accessed August 13, 2008.

5 .American Heart Association. Heart Disease and Stroke Statistics - 2008 Update. http://www.americanheart.org/downloadable/heart/1200082005246HS_Stats%20200 8.f inal.pdf. Accessed August 13, 2008.

6. British Heart Foundation Health Promotion Research Group. European Cardiovascular Disease Statistics 2008, http://www.ehnheart.org/files/statistics%202008%20web-161229A.pdf, Accessed A
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SOURCE Eli Lilly and Company
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