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Prasco Expands Authorized Generic Product Line with Vancocin® HCl Capsules
Date:4/11/2012

ncomycin.  Vancomycin Hydrochloride Capsules must be given orally for treatment of staphylococcal enterocolitis and CDAD.  Orally administered Vancomycin Hydrochloride Capsules are not effective for other types of infections.  Clinically significant serum concentrations have been reported in some patients who have taken multiple oral doses of Vancomycin Hydrochloride Capsules for active CDAD.  Monitoring of serum concentrations may be appropriate in some instances. 

Nephrotoxicity has occurred following oral Vancomycin Hydrochloride Capsules therapy and can occur either during or after completion of therapy. The risk is increased in geriatric patients.  Monitor renal function.  Ototoxicity has occurred in patients receiving Vancomycin Hydrochloride Capsules.  Assessment of auditory function may be appropriate in some instances.  Prescribing Vancomycin Hydrochloride Capsules in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug resistant bacteria.  In clinical trials, the most common adverse reactions (greater than or equal to 10 percent) were nausea (17 percent), abdominal pain (15 percent), and hypokalemia (13 percent).  Patients over 65 years of age may take longer to respond to therapy compared to patients less than 65 years of age.  Clinicians should be aware of the importance of appropriate duration of Vancomycin Hydrochloride Capsules treatment in patients over 65 years of age and not discontinue or switch to alternative treatment prematurely. 

For Vancomycin Hydrochloride Capsules prescribing information, please visit: http://www.prasco.com/downloads/Product%20PIs/66993-211-19.pdf

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