Navigation Links
Pradaxa Gains Preferred Formulary Status with Key Pharmacy Benefit Managers
Date:3/14/2011

ations and Usage

PRADAXA is indicated to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

IMPORTANT SAFETY INFORMATION ABOUT PRADAXA

CONTRAINDICATIONS

PRADAXA is contraindicated in patients with active pathological bleeding and patients with a known serious hypersensitivity reaction (e.g., anaphylactic reaction or anaphylactic shock) to PRADAXA.

WARNINGS AND PRECAUTIONS

Risk of Bleeding

PRADAXA increases the risk of bleeding and can cause significant and, sometimes, fatal bleeding.

Risk factors for bleeding include:

- Medications that increase the risk of bleeding in general (e.g., anti-platelet agents, heparin, fibrinolytic therapy, and chronic use of NSAIDs).

-Labor and delivery

Promptly evaluate any signs or symptoms of blood loss, such as a drop in hemoglobin and/or hematocrit or hypotension. Discontinue PRADAXA in patients with active pathological bleeding.

Temporary Discontinuation of PRADAXA

Discontinuing PRADAXA for active bleeding, elective surgery, or invasive procedures places patients at an increased risk of stroke.  Lapses in therapy should be avoided, and if PRADAXA must be temporarily discontinued for any reason, therapy should be restarted as soon as possible.

Effect of P-gp Inducers and Inhibitors on PRADAXA Exposure

The concomitant use of PRADAXA with P-gp inducers (e.g., rifampin) reduces dabigatran exposure and should generally be avoided. P-gp inhibitors ketoconazole, verapamil, amiodarone, quinidine, and clarithromycin, do not require dose adjustments. These results should not be extrapolated to other P-gp inhibitors.

ADVERSE REACTIONS

In the pivotal trial comparing PRADAXA to warfarin, the most frequent adverse reactions leading to discontinuation of PRADAXA were bleeding and gastrointestinal (GI) even
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. New Sub-Analysis of RE-LY Trial Examines Pradaxa in Patients with Atrial Fibrillation Undergoing Cardioversion
2. New Analyses of Data From RE-LY Trial, Involving Oral Anticoagulant Pradaxa, to be Presented at American Heart Associations Scientific Sessions
3. Boehringer Ingelheims Pradaxa Available in U.S. Pharmacies Starting Wednesday, November 3
4. FDA Approves Pradaxa, Marking a Major Milestone to Reduce the Risk of Stroke in Patients with Non-Valvular Atrial Fibrillation
5. FDA Approves Pradaxa to Prevent Stroke in People With Atrial Fibrillation
6. Woman Files Suit in Beaumont, Texas Federal Court Against DePuy Orthopaedics and Johnson & Johnson Over Recalled Hip Device
7. Woman Files Suit in Federal Court Against DePuy Orthopaedics, Inc.,/Johnson & Johnson Over Recalled Hip Device
8. Cellceutix Discovers Drug Activates Guardian Angel p53 in Fight Against Leukemia
9. OncoMed Anti-Cancer Stem Cell Antibody OMP-21M18 Demonstrates Potent Activity in Preclinical Studies Against Human Colon Cancer Tumors Regardless of KRAS Mutation Status
10. Plexus Biomedical Inc. Gains FDA Approval of the First Medical Device to Help Prevent External Hemorrhoids During Vaginal Childbirth
11. FDA Warns Against Certain Uses of Asthma Drug Terbutaline for Preterm Labor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... Research and Markets  has announced the ... 2014" report to their offering. ... professional and in-depth study on the current state of ... provides a basic overview of the industry including definitions, ... market analysis is provided for the international markets including ...
(Date:8/27/2014)... Aug. 27, 2014   Los Angeles orthodontics ... Aura to patients who want to make their treatment ... at the OrthoSpaceship, all patients have a powerful tool ... system can be used by most patients with all ... progress by using the AcceleDent® Aura system for a ...
(Date:8/27/2014)... 27, 2014 ISPE , the International ... released a preview of its Drug Shortages Prevention ... drug shortages and maintain a robust and reliable supply ... Plan, a first for the industry, was developed by ... and describes how industry can best prevent drug shortages ...
Breaking Medicine Technology:Global Pulse Oximeter Industry Report 2014 2Los Angeles Orthodontist, Dr. Isaac Hakim, is Now Offering AcceleDent Aura 2ISPE Releases First Look at its Plan to Prevent Drug Shortages 2ISPE Releases First Look at its Plan to Prevent Drug Shortages 3ISPE Releases First Look at its Plan to Prevent Drug Shortages 4
(Date:8/27/2014)... Washington, DC (PRWEB) August 28, 2014 ... that Betty Pierce Dennis, DrPH, MN, RN, FAAN, became ... Nursing Center for the Advancement of the Science of ... one of seven that comprise the NLN Home for ... the nation’s capital a year ago. , Under ...
(Date:8/27/2014)... Recently, Skmen.com, a renowned garment manufacturer and retailer, ... dresses . The company has rich experience in making ... in stock and ready to ship: celebrity bodycon dresses, ... dresses and so forth. All of them are available ... are proud to announce the new collection of celebrity ...
(Date:8/27/2014)... 2014 Philadelphia, PA. Inc. magazine ... Inc. 500 list, an exclusive ranking of the nation’s ... comprehensive look at the most important segment of the ... gained early exposure as members of the Inc. 500 ... , “Some of world’s greatest companies have had ...
(Date:8/27/2014)... (PRWEB) August 28, 2014 All Canada ... hoods, they can go from classic to modern. With unique ... system, each of them is a step up in opulence. ... Canada Goose Banff Parkas for 2014. , True ... is now offering great discounts (up to 28% off) on ...
(Date:8/27/2014)... Los Angeles, CA (PRWEB) August 27, 2014 ... used to require a consumer to present personal information ... is changing the way that life insurance quotes are ... . , The term plans that an adult ... are provided by known U.S. companies. The system for ...
Breaking Medicine News(10 mins):Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 2Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 3Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 4Health News:Skmen.com Unveils Its New Celebrity Bodycon Dresses for Its Loyal Customers 2Health News:Inc Magazine Unveils 33rd Annual List of America's Fastest-Growing Private Companies - the Inc. 500 2Health News:CanadaGooseJackor.nu: 2014 Canada Goose Banff Parkas At Discounted Prices 2Health News:Life Insurance Quotes for Term Policies Now Found at Insurer Website Online 2
... dating has not only shed its stigma, it has ... other than meeting through friends, according to a new ... The digital revolution in romance is a boon ... potential partners, reports the team of psychological scientists who ...
... , FRIDAY, Feb. 3 (HealthDay News) -- ,Extended synaptic development ... new study suggests. During the first few years of ... information and experiences from the environment in a way that ... This is due to extended synaptic development, according to the ...
... been mapped with unprecedented accuracy in the bloodstream of ... brand new approach, in an attempt to assess and ... through the body, and solve the problem of predicting ... to a previous generation of systems, the researchers state ...
... aged 70 and over will increase by 40% in ... over will more than double1. Health authorities and the ... of people suffering costly and debilitating age-related chronic diseases ... dementia. The significant increase in the numbers of people ...
... (February 1, 2012) Rates of diabetes vary widely across ... by Dr. Longjian Liu of Drexel University,s School of ... diabetes now live in developing countries. Liu,s study found ... in developing countries, and that one in 10 diagnosed ...
... , THURSDAY, Feb. 2 (HealthDay News) -- Sometimes, there,s nothing ... that where the itch resides is key to ... understanding of itch and might even help folks battling itchy ... professor of dermatology at Wake Forest Baptist Medical Center in ...
Cached Medicine News:Health News:Online dating research shows cupid's arrow is turning digital 2Health News:Online dating research shows cupid's arrow is turning digital 3Health News:Why Human Brains Are Smarter Than Chimp Brains 2Health News:New technology to tackle treatment-resistant cancers 2Health News:New study to assess 3 simple, cost-effective strategies to promote healthy aging 2Health News:Diabetes rates vary widely in developing countries, 1 in 10 cases untreated 2Health News:Pleasure in Scratching an Itch May Depend on Location 2
... stylish Thalia eyeglasses eyewear collection ... appeal of the renowned Latin ... of eyeglasses eyewear is ultra-sleek, ... ophthalmic styles that include decorative ...
... a remarkable sunwear collection, affectionately known as ... of the benefits of the Titan Minimal ... top quality sun lenses that offer 100% ... They provide the most comfortable, lightweight sun ...
... The name Silhouette stands for ... It all began in 1964 with ... five and a novel, pioneering approach: ... a simple implement to improve faulty ...
... something that almost all retailers must address ... with VALUE - not just in price ... Research shows that National is among the ... ,National offers an exciting collection of contemporary ...
Medicine Products: