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Pradaxa Gains Preferred Formulary Status with Key Pharmacy Benefit Managers
Date:3/14/2011

ment that has demonstrated significant reductions in the risk of stroke compared to warfarin in patients with NVAF(2) and is the first oral anticoagulant to be approved in the U.S. in more than 50 years in this patient population.

About Atrial Fibrillation and Stroke

Atrial fibrillation, characterized by an irregular heartbeat,(3) can cause blood clots to form in the heart that can travel to the brain and cause a stroke.(3) An estimated 2.3 million Americans are living with atrial fibrillation,(4) and the prevalence is expected to increase to 5.6 million by 2050.(4) Non-valvular atrial fibrillation, which accounts for up to 95 percent of diagnosed cases of atrial fibrillation,(4) refers to cases of atrial fibrillation without rheumatic mitral valve disease, prosthetic heart valve or valve repair, according to the 2006 ACC/AHA/ESC guidelines.(5)  Atrial fibrillation increases the risk of stroke nearly five times(5) and is associated with up to 15 percent of all strokes in the U.S.(5) Atrial fibrillation imposes a substantial economic burden to the healthcare system,(6) specifically the high costs associated with stroke.(7)

About the Storage and Handling of PRADAXA

PRADAXA must be stored in its original packaging(2) and patients should not transfer the capsules to pill boxes or pill organizers.(1) Once the bottle is opened, the product must be used within 30 days.(2) Patients must close the bottle tightly immediately after removing one capsule(2) and must not alter the child-proof cap.(1) It is recommended that patients date the bottle to expire 30 days after first opening. When more than one bottle is dispensed, patients should only open one bottle at a time.(1) When packaged in a blister package, each capsule should only be removed at time of use.(2) After 30 days, patients should safely throw away any unused PRADAXA capsules.(2)

About Pradaxa® (dabigatran etexilate) Capsules

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SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
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Related medicine technology :

1. New Sub-Analysis of RE-LY Trial Examines Pradaxa in Patients with Atrial Fibrillation Undergoing Cardioversion
2. New Analyses of Data From RE-LY Trial, Involving Oral Anticoagulant Pradaxa, to be Presented at American Heart Associations Scientific Sessions
3. Boehringer Ingelheims Pradaxa Available in U.S. Pharmacies Starting Wednesday, November 3
4. FDA Approves Pradaxa, Marking a Major Milestone to Reduce the Risk of Stroke in Patients with Non-Valvular Atrial Fibrillation
5. FDA Approves Pradaxa to Prevent Stroke in People With Atrial Fibrillation
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