Navigation Links
Pradaxa® (dabigatran etexilate mesylate) Capsules Gains Preferred Formulary Status with AARP®, Nation's Largest Provider of Medicare Part D Coverage
Date:5/19/2011

PRADAXA is indicated to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

IMPORTANT SAFETY INFORMATION ABOUT PRADAXA

CONTRAINDICATIONS

PRADAXA is contraindicated in patients with active pathological bleeding and patients with a known serious hypersensitivity reaction (e.g., anaphylactic reaction or anaphylactic shock) to PRADAXA.

WARNINGS AND PRECAUTIONS

Risk of Bleeding

PRADAXA increases the risk of bleeding and can cause significant and, sometimes, fatal bleeding.

Risk factors for bleeding include:

- Medications that increase the risk of bleeding in general (e.g., anti-platelet agents, heparin, fibrinolytic therapy, and chronic use of NSAIDs).

-Labor and delivery

Promptly evaluate any signs or symptoms of blood loss, such as a drop in hemoglobin and/or hematocrit or hypotension. Discontinue PRADAXA in patients with active pathological bleeding.

Temporary Discontinuation of PRADAXA

Discontinuing PRADAXA for active bleeding, elective surgery, or invasive procedures places patients at an increased risk of stroke.  Lapses in therapy should be avoided, and if PRADAXA must be temporarily discontinued for any reason, therapy should be restarted as soon as possible.

Effect of P-gp Inducers and Inhibitors on PRADAXA Exposure

The concomitant use of PRADAXA with P-gp inducers (e.g., rifampin) reduces dabigatran exposure and should generally be avoided. P-gp inhibitors ketoconazole, verapamil, amiodarone, quinidine, and clarithromycin, do not require dose adjustments. These results should not be extrapolated to other P-gp inhibitors.

ADVERSE REACTIONS

In the pivotal trial comparing PRADAXA to warfarin, the most frequent adverse reactions leading to discontinuation of PRADAXA were bleeding and gastrointestinal (GI) events. PRADAXA 150 mg resulted in a
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Data Published in The Lancet Compare Dabigatran Etexilate to Dose-Adjusted Warfarin Across RE-LY® Trial Centers
2. FDA Approves Vyvanse® (lisdexamfetamine dimesylate) Capsules CII for the Treatment of ADHD in Adolescents
3. FDA Approves Labeling Change for Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII to Include Supplemental Data Demonstrating Significant Efficacy at Two Hours Through 14 Hours After Administration in Adults with ADHD
4. Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII
5. New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)
6. Recent Study Demonstrated VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Improvements in Behavior, Inattention, and Math Test Scores from 1.5 Hours up to 13 Hours following Administration in Children with ADHD
7. Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD
8. Results of the Phase III Pivotal Study of VYVANSE(TM) (Lisdexamfetamine Dimesylate) for the Treatment of ADHD in Adults Presented at National Scientific Meeting of Psychiatrists
9. Results Of VYVANSE(TM) (lisdexamfetamine dimesylate) Effect Size Analysis Presented at Major Scientific Meeting
10. Results of VYVANSE(TM) (lisdexamfetamine dimesylate) Pivotal Trial in Adult ADHD Presented at Major Scientific Meeting
11. Mylan Launches First Generic Version of Amrix® Capsules
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... and NEW YORK , May 27, ... - Over 70% Indonesian men (80 million) are ... annually due to smoking-related conditions; of these, 6% are ... vehicles in Jakarta do not ... is the fourth most populous country in ...
(Date:5/27/2015)... RUTHERFORD, N.J. , May 27, 2015  Cambrex Corporation ... Sargen , Executive Vice President and Chief Financial Officer, will ... 3, 2015 at 8:00 a.m. EDT in New ... and slide presentation can be accessed from the Cambrex website ... & Presentations", and a replay will be available for 90 ...
(Date:5/27/2015)... , May 27, 2015  Novartis will ... in 21 medicines and 11 investigational compounds across ... American Society of Clinical Oncology (ASCO) Annual Meeting, ... European Hematology Association (EHA), June 11-14. Data will ... cancer types, including melanoma, lung, breast, kidney and ...
Breaking Medicine Technology:Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 2Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 3Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 4Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 2Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 3Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 4Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 5Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 6Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 7Novartis presents new data on 21 medicines and 11 investigational compounds at ASCO and EHA 8
(Date:5/27/2015)... ABILENE, Texas (PRWEB) May 27, 2015 ... addition of three FDA-approved dermal filler treatments in Abilene, ... designed to reduce the appearance of glabellar lines, better ... lines. Belotero Balance® is designed to treat smoker’s ... mouth to the chin, while Radiesse® improves the appearance ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 Coco Libre announced ... be able to reach for Organic Coconut Water to quench ... will be available at VIP areas, artist greenrooms, corporate skyboxes ... available at area hotels and on festival shuttle buses. ... this year,” said Noa Elan, Director of Strategic Partnerships for ...
(Date:5/27/2015)... Arizona (PRWEB) May 27, 2015 Genius ... of their advanced programmatic marketing technology, they have boosted ... advertising support on a regional level for seven Utah-based ... marketing was through television and radio media. In 2014 ... with the help of Genius Monkey , shifted ...
(Date:5/27/2015)... May 27, 2015 With a prevalently ... poll conducted during the "ACA - Controlling the Chaos" ... 75% are currently in the process of researching ... were confidently prepared for the reporting mandates. , According ... the webinar, those who are currently vetting ACA reporting ...
(Date:5/27/2015)... May 27, 2015 Decorview , ... America, is offering free design advice to homeowners looking ... , “Light pollution caused by streetlights, outdoor signs, ... restless night’s sleep, said Kim Rush, VP of sales ... cities across North America with recently installed LED streetlights– ...
Breaking Medicine News(10 mins):Health News:The MedSpa at Hendrick Introduces Xeomin®, Belotero Balance® and Radiesse® Injectables 2Health News:Coco Libre Puts Organic Coconut Water on the Line-up at BottleRock Napa 2Health News:Genius Monkey Boosts Utah Honda Dealers Website Traffic 142% 2Health News:Employers are On Track for ACA Reporting According to Businessolver Poll 2Health News:Decorview Helps Homeowners Combat Light Pollution 2
... 10-page letter addressed to Donald Berwick, administrator of the ... The ACP strongly supports the intent of the ... potential of supporting such important care delivery goals as ... pleased that,the foundation of care under this payment model, ...
... Hartford Faculty Scholars Program has granted 11 geriatric ... development, mentorship, and support for projects that will improve healthy ... the awards this year is a partnership with the ... the current awardees are PhD-level social workers from the VA ...
... HealthDay Reporter , THURSDAY, June 2 (HealthDay ... regular exercise as part of the plan, don,t appear ... "It,s pretty clear low-carb is effective for weight ... clinical and research exercise physiology at the Johns Hopkins ...
... are evaluated for liver diseases such as hepatitis C ... the extent of disease progression. For patients who question ... alternatives options to consider. Elastography and serum markers are ... in the June issue of Hepatology , a ...
... , THURSDAY, June 2 (HealthDay News) -- Young children ... from anxiety, loneliness, low self-esteem and sadness, they experience ... new research suggests. Children do not fall behind ... period before their parents divorce, the study revealed. Instead, ...
... study from North Carolina State University shows that talking about ... transgender community. The finding may help efforts to promote safer ... and also sheds light on broader questions related to safer ... is the fact that we,re seeing evidence of devastatingly high ...
Cached Medicine News:Health News:Supportive of intent of ACO proposed rule, ACP expresses concern 2Health News:Supportive of intent of ACO proposed rule, ACP expresses concern 3Health News:Hartford Program issues geriatric social work awards, forms VA partnership 2Health News:Hartford Program issues geriatric social work awards, forms VA partnership 3Health News:Low-Carb, High-Fat Diets May Not Pose Risk to Arteries 2Health News:Low-Carb, High-Fat Diets May Not Pose Risk to Arteries 3Health News:Noninvasive diagnostics may offer alternative to liver biopsy for assessing liver fibrosis 2Health News:Divorce Can Hurt Kids' Math Scores, Friendships 2Health News:Divorce Can Hurt Kids' Math Scores, Friendships 3Health News:Safer sex: Study examines sexual communication in transgender community 2
... Ruschelit® PVC. 2 eyes, oral. ... patient age. X-ray opaque line. Graduated. ... access. Designed to reduce kinking of ... curvature. Thermosensitive Ruschelit® PVC adapts to ...
... PVC. 2 eyes, oral. Marked with ... X-ray opaque line. Graduated. Single use. ... reduce kinking of the tube by ... adapts to the anatomical situation at ...
... Slick Set® Tube with stylet inside. ... quality cuffed Rusch endotracheal tube with ... to use saving you time and ... coded for easy identification and has ...
Ruschelit® PVC. Murphy eye-nasoral. Black positioning ring. High volume/low pressure cuff. X-ray opaque line. Graduated. Single use....
Medicine Products: