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Practice Guidelines Confirm Utility of Endoscopic Radiofrequency Ablation (RFA) for the Treatment of Barrett's Esophagus
Date:3/9/2011

SUNNYVALE, Calif., March 10, 2011 /PRNewswire/ -- BARRX Medical, Inc., a leader in developing minimally invasive medical devices to remove precancerous tissue from the gastrointestinal tract, reported today that the American Gastroenterological Association (AGA) has issued the AGA Medical Position Statement on the Treatment of Barrett's Esophagus. The guideline recommends removal of precancerous cells in patients with confirmed high-grade Barrett's esophagus utilizing endoscopic eradication therapy, such as radiofrequency ablation (RFA) technology as delivered by the BARRX HALO Ablation System.

To provide the basis for the medical position statement, a technical review of the literature was conducted to explore a series of questions regarding management of Barrett's esophagus. The technical review was submitted to a medical position panel consisting of a diverse group of stakeholders, including gastroenterologists, a general surgeon, a pathologist, a health plan representative, and a consumer/patient advocate. The medical position statement was then created, which includes information affirming the utility of RFA therapy as a treatment option for eradication of Barrett's esophagus.

More specifically, the medical position statement recommends endoscopic eradication therapy – such as RFA – for patients with confirmed high-grade dysplasia (advanced precancerous cells) as opposed to watchful waiting or immediate esophagectomy. For patients with confirmed low-grade dysplasia (less advanced precancerous cells), endoscopic eradication therapy is recommended as a therapeutic option and should be discussed with patients as such.

Patients who present with non-dysplastic (early precancerous cells) Barrett's, the AGA states, "Although endoscopic eradication therapy is not suggested for the general population of patients with Barrett's esophagus in the absence of dysplasia, we suggest that RFA, with or without endoscopic mucosal resection (EM
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SOURCE BARRX Medical, Inc.
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