Navigation Links
Potential Mechanism of Action Identified for the Treatment of Major Depression With Trigeminal Nerve Stimulation (TNS) - The USB Port to the Brain™
Date:7/5/2011

LOS ANGELES, July 5, 2011 /PRNewswire/ -- NeuroSigma, a Los Angeles-based neuromodulation company, today announced that a recent Phase I clinical trial revealed that external Trigeminal Nerve Stimulation (eTNS™) increased regional cerebral blood flow in brain regions associated with depression and mood regulation.  eTNS™ was shown to be a potential therapy for depression, with significant reductions in depression severity during the 8-week adjunctive treatment period.  These encouraging results have led to a Phase II double-blind trial with expected completion later this year.

(Photo: http://photos.prnewswire.com/prnh/20110705/NY29679 )

eTNS™ and Depression

Trigeminal Nerve Stimulation (TNS) is a promising new therapy for the treatment of major depression without the typical side effects of antidepressants.  TNS was invented by researchers at UCLA and is exclusively licensed to NeuroSigma.  

In June of last year, UCLA investigators reported preliminary results from the first five patients of the open-label Phase I TNS feasibility trial, noting a 70% reduction in symptom severity over the 8-week acute phase of treatment, resulting in an 80% remission rate. (http://newsroom.ucla.edu/portal/ucla/non-invasive-therapy-significantly-169741.aspx).  

Last month, at the New Clinical Drug Evaluation Unit (NDCEU) 51st Annual Meeting in Boca Raton, Florida, Ian Cook, M.D., the Joanne and George Miller Family Chair in Depression Research at the Semel Institute at UCLA, and a medical advisor to NeuroSigma, presented additional data from four new subjects enrolled in this Phase I trial, which included functional neuroimaging PET data.  Cook noted that "with just brief exposure to eTNS™, significant increases in regional cer
'/>"/>

SOURCE NeuroSigma, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
2. Cleveland Clinic Researchers Identify Mechanism Behind Platelet Function and Potentially Fatal Blood Clot Formation
3. Peregrine Reports Data Showing Bavituximabs Potential to Shrink Prostate Tumors
4. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
5. TorreyPines Therapeutics Completes Phase I Multiple Dose Clinical Trial of NGX267, a Selective M1 Agonist for the Potential Treatment of Cognitive Impairment Associated with Schizophrenia
6. Intellect Neurosciences, Inc. and CHDI, Inc. Enter Into Compound Testing Agreement to Evaluate OXIGON(TM) as a Potential Treatment for Huntington Disease
7. Study Published in Endocrinology Reports Potential of Modigene Technology to Extend Duration of Protein Drugs
8. Potential Breakthrough Cancer Treatment Emerges from MIPS-Funded Clinical Trial Teaming CSA Medical Inc. and University of Maryland Researchers
9. Synvista Therapeutics Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications
10. Potential Early Warning System for Lung Cancer Identified
11. Preclinical Studies Show Potential Progress Toward Identifying Specific Tumor Types With Higher Likelihood of Demonstrating Response to Anti-Cancer Compounds Early in Clinical Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)...   Hospira, Inc. (NYSE: HSP ... infusion technologies, today announced that the company will present ... Wednesday, Jan. 14, 2015, in San Francisco.  ... 10:30 a.m. Pacific time on Wednesday, Jan. 14, 2015.  ... a live audiocast accessible via the Investor Relations section ...
(Date:12/19/2014)... , December 18, 2014 ... software application/module that is used to store, manipulate, ... RIS comprises a patient tracking and scheduling system, ... integration of RIS with HIS and other databases ... patient registration and patient scheduling, patient list management, ...
(Date:12/19/2014)... 18, 2014 Capnia, Inc. (NASDAQ: ... medical diagnostics based on its proprietary Sensalyze™ Technology ... announced financial results for the third quarter and ... "Following the completion of our initial public offering ... the recently initiated CoSense® commercial launch," said Anish ...
Breaking Medicine Technology:The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8
(Date:12/21/2014)... Coral Gables, FL (PRWEB) December 21, 2014 ... of head lice, who do they call? The new answer ... Leon Blvd, Coral Gables FL 33134, their newest treatment center ... eradicate this pest quickly, conveniently and without the use of ... Grand Opening is scheduled for January 1, 2015. Like the ...
(Date:12/21/2014)... York, NY (PRWEB) December 21, 2014 ... nearing 1,400 in a consolidated litigation underway in New ... documents, a total of 1,375 claims involving the birth ... Superior Court. These lawsuits were filed by women who ... to have led to uterine perforations and other complications ...
(Date:12/21/2014)... Portland, OR (PRWEB) December 21, 2014 ... discussing some of the issues and systemic barriers for ... ITU World Paratriathlon Champion. Scheidies has a condition called ... over time. He describes how he adapted his athletic ... to use his success in triathlon to pioneer the ...
(Date:12/21/2014)... Concept Plus, LLC. a SDB and ... Fairfax, VA., today announced it has been recognized by ... which ranks the fastest growing government contracting small businesses by ... , This is the first year that Concept Plus, LLC., ... with a 95.92% compound annual growth rate. “For Concept Plus ...
(Date:12/20/2014)... NY (PRWEB) December 20, 2014 An ... healthcare sector have benefited the Massage Services ... discretionary characteristics of industry products, the anticipated 1.0% annualized ... period has provided consumers with the means to afford ... have received a massage in a given year has ...
Breaking Medicine News(10 mins):Health News:All-Natural Florida Lice Removal Company Opens New Lice Treatment Salon In South Florida 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 3Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 2Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 3Health News:Concept Plus, LLC. Named One of Washington Technology’s Fast 50 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3
... SAN JOSE, Calif., Jan. 18 VNUS(R) Medical,Technologies, Inc. ... devices,for the minimally invasive treatment of venous reflux disease, ... Officer and,Vice President of Finance and Administration., Mr. ... experience in,various senior leadership roles. Mr. Osborne had served ...
... is it difficult to pick out even a familiar ... the phenomenon has been poorly understood until now. The ... individuals with face-recognition disorders and visual-attention related ailments ... system that approaches the sophistication of human visual perception. ...
... hantavirus infection spread among humans? , In connection with last ... has managed for the first time to show that hantavirus ... whether this contagion can spread among humans. , In Sweden, ... epidemica occurs primarily in the northern parts of the country. ...
... Just Kids Founder, Adams, Reaches Finals of 6th Annual Volvo ... Select and Unveil Top Four Winners March 19 at Volvo,for life Awards Ceremony in ... ... Life, IRVINE, Calif., Jan. 18 For the past nine weeks,hundreds of ...
... tumors, dual implantation of radioactive seeds and chemotherapy ... study led by specialists at the Neuroscience Institute ... Hospital. , The study, published in the February ... patients treated with simultaneous implantation of radioactive seeds ...
... and child nutrition interventions were implemented in poor countries, cases ... third, and deaths by up to a quarter, according to ... the London School of Hygiene & Tropical Medicine, is one ... of the Lancet Maternal and Child Undernutrition Series, which is ...
Cached Medicine News:Health News:VNUS Medical Technologies Appoints Peter Osborne as Chief Financial Officer 2Health News:Face facts: People don't stand out in crowds 2Health News:Can hantavirus infection spread among humans? 2Health News:America Selects Earlham Resident Marilyn Adams as One of the Nation's Top Hometown Heroes 2Health News:America Selects Earlham Resident Marilyn Adams as One of the Nation's Top Hometown Heroes 3Health News:America Selects Earlham Resident Marilyn Adams as One of the Nation's Top Hometown Heroes 4Health News:America Selects Earlham Resident Marilyn Adams as One of the Nation's Top Hometown Heroes 5Health News:Combined radiation seed, chemotherapy wafer implants show promise in treating cancerous brain tumors 2Health News:One-third of stunting and a quarter of deaths among under 3s in poor countries could be prevented 2
... Single Use Articulating linear stapler ... ,LACTOMER™ 9-1 is a ... ,The Auto Suture™ ROTICULATOR ... staplers are for use in ...
... stapler with LACTOMER™ 9-1 absorbable staples., ... CS™-57 disposable surgical stapler has application ... opening, such as a hysterotomy made ... transecting muscle tissue, to maintain alignment ...
... Loading Units With Titanium Staples ... TA™ (Single Use Reloadable Stapler ... Auto Suture™ PREMIUM MULTIFIRE TA™ ... gynecological, pediatric and thoracic surgical ...
... Single Use Loading Units ... Series™ (Single Use Reloadable Staplers ... Auto Suture™ TA™ Reloadable staplers ... pediatric and thoracic surgical procedures ...
Medicine Products: