Navigation Links
Post-Hoc Data Show Daily Activity Participation, Independence and Sleep Quality Improved in Adults with Moderate to Severe Rheumatoid Arthritis After Treatment with ORENCIA(R) (Abatacept)
Date:11/12/2007

in the placebo group (p-value less than 0.0001) sleep problems Index I was -9.5 in the ORENCIA group and -1.4 in the placebo group (p-value less than 0.0001) and Index II was -9.8 in the ORENCIA group and -2.1 in the placebo group (p-value less than 0.0001). MOS-sleep scales measuring awakened short of breath or with headache and snoring were not significantly different in the ATTAIN group. In the AIM study, measurement of sleep disturbance in the ORENCIA group was -13.0 and -8.9 in the placebo group (p-value equals 0.0197), sleep problems Index I was -9.4 in the ORENCIA group and -6.7 in the placebo group (p-value equals 0.0476) and Index II was -10.4 in the ORENCIA group and -7.3 in the placebo group (p-value equals 0.0173). MOS-sleep scales measuring awakened short of breath or with headache, snoring, adequacy or drowsiness were not significantly different in the AIM group.

About AIM and ATTAIN

AIM was a Phase III multi-center, randomized, double-blind, placebo- controlled trial with 652 patients treated at baseline who had active RA despite MTX therapy (638 included in efficacy analyses). The study was double-blind through one year, followed by an ongoing, open-label, long-term extension study. A total of 376 (from the original 424) patients in the group treated with ORENCIA(R) (abatacept) entered the long-term extension study. Additional DMARDs, non-steroidal anti-inflammatory drugs (NSAIDs), and aspirin were added and/or adjusted at the discretion of the investigator in the long- term extension study. Primary reasons for discontinuation in the long-term extension studies were adverse events, withdrawal of consent, and lack of efficacy.

Primary endpoints were ACR 20 at six months ORENCIA vs. placebo (67.9 percent vs. 39.7 percent, respectively; p-value less than 0.001), clinically significant improvement in HAQ-DI at one year (63.7 percent vs. 39.3 percent, respectively; p-value less than 0.001), erosion score at one year (mean change from bas
'/>"/>

SOURCE Bristol-Myers Squibb Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. New Phase 3 Study in Treatment-Naive Adults with HIV Evaluates Efficacy and Safety of Once-Daily PREZISTA(TM)/ritonavir vs. KALETRA(R) as Part of HIV Combination Therapy
2. New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy
3. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
4. Potent Hepatitis C Virus Inhibitors Show Efficacy and Potential for Once Daily Dosing in Preclinical Studies
5. ISTA Pharmaceuticals Presents Results from Two Phase III Clinical Trials of Xibrom(TM) QD (Once-daily) Formulation at the American Academy of Ophthalmology Annual Meeting
6. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
7. R7128 Demonstrates Safety and Potent Antiviral Activity in HCV-Infected Patients
8. Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria
9. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
10. Oritavancin Demonstrates Potent and Rapid In Vitro Activity Against MRSA, VRE and Other Strains of Resistant Bacteria
11. Proteolix Initiates Multicenter Open-label Study of the Safety and Activity of Carfilzomib in Subjects With Relapsed Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... 2015 /PRNewswire/-- Harwood Feffer LLP ( www.hfesq.com ) is investigating ... Inc. ("Advaxis" or the "Company") (NASDAQ: ADXS ... duties to shareholders. On January 21, 2015, ... that Advaxis had misrepresented the clinical data for its ...
(Date:1/23/2015)... 23, 2015  Now available for sale, The Armor1 Ankle ... prevents ankle sprains by cushioning the ankle from an ... around the outside of any shoe type and allows ... still offering protection against sprains. With customers in physical ...
(Date:1/23/2015)... , Jan. 23, 2015 Cord Blood America, Inc. ( ... or the "Company")  filed a Preliminary Proxy Statement, Schedule 14A, ... today, and provides an update for shareholders detailing why a ... requested. Dear Shareholders, As we reflect ...
Breaking Medicine Technology:Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4
(Date:1/22/2015)... Illinois (PRWEB) January 22, 2015 Deer Path ... will host a Valentine’s Day Happy Hour from 3 p.m. to ... at 12500 Regency Parkway in Huntley, Illinois, serves adults with physical ... Hour event will include Valentine's Day treats, games and sweetheart-themed karaoke. ...
(Date:1/22/2015)... with its top dressmaking technologies, has been a leading dress ... its latest designs of wedding dresses and launching a site-wide ... all the fresh new products are designed for 2015, and ... off. All the clothes from LunaDress follow up with the ...
(Date:1/22/2015)... Chemo Duck Program is pleased to announce the release of the ... with cancer. The Chemo Duck App, available on iTunes for use ... to help children of all ages living with cancer adjust to ... entertained, educated and at ease while waiting for clinic visits or ...
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method put ... muscle by up to 30lbs in less than 12 weeks ... Stan Stevenson, prompting an investigative review. , “Our Incredible ... diet formula that allows the body to pack on a ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently released ... website of AngelWeddingDress.com to find more details. , ... for a bridal party. AngelWeddingDress offers a variety of ... maternity wedding dresses are specially designed for 2015. , ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2
... , , , ... unveiling a new online pre s s room ... resources available to journalists. , , The goal of the ... issues in veterinary medicine as easy as possible for journalists and also to ...
... , , ALLEGAN, Mich., Aug. ... today announced that its Board of Directors declared a quarterly ... to shareholders of record on August 28, 2009. ... global healthcare supplier that develops, manufactures and distributes over-the-counter (OTC) ...
... Aug. 13 Shamir Optical Industry Ltd. (Nasdaq: SHMR ... technology to the ophthalmic lens market, today announced unaudited financial results ... For the quarter ended June 30, 2009, revenues were ... period in 2008. The decrease in revenues was mainly due to ...
... Hospital Aintree, the University of Warwick and researchers in Sweden, ... have raised levels of a protein called SPARC, that can ... in insulin, a hormone that controls blood sugar levels, and ... in SPARC, which can prevent the proper storage of fat ...
... A new look at a large database of prostate cancer ... to increasing the risk of recurrence after surgery: Being way ... at Duke University Medical Center. Studies have shown ... cancers, including prostate cancer. Because blacks are more likely ...
... , , CARDIFF, ... JEDM) ( http://www.jedimindinc.com ) announced today that a " 60 Minutes ... credibility to "mind control" software and hardware applications. During the "60 ... is basically an EEG cap that reads signals from the brain. ...
Cached Medicine News:Health News:AVMA Unveils Improved Online Press Room to Help Journalists 2Health News:AVMA Unveils Improved Online Press Room to Help Journalists 3Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 2Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 3Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 4Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 5Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 6Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 7Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 8Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 9Health News:Shamir Optical Industry Ltd. Reports Second Quarter 2009 Results 10Health News:Scarring key to link between obesity and diabetes 2Health News:Obesity increases risk of prostate cancer recurrence for both blacks and whites 2Health News:Mind Control Goes Mainstream on CBS's '60 Minutes' 2
For use with E5381 700 Circling Band (240 style). 1.65 mm diameter, 30.0 mm long....
For use under curved implants. Indications: When additional buckling is required in the meridional direction. Overall length: 10.4 mm....
For use with E5381 600 Circling Band (40 style). 2.2 mm diameter, 28.5 mm long....
Used in conjunction with the E5381 700 Circling Band (240 style). Indications: When high buckle is required. Overall length: 11.6 mm....
Medicine Products: