Navigation Links
Post-Hoc Data Show Daily Activity Participation, Independence and Sleep Quality Improved in Adults with Moderate to Severe Rheumatoid Arthritis After Treatment with ORENCIA(R) (Abatacept)
Date:11/12/2007

nal scale that included these two factors.

Change in mean score on Factor 1 (socio-emotional role independence) was 0.921 for the ORENCIA group and 0.169 for the placebo group (p-value less than 0.0001). Change in mean score on Factor 2 (physical independence) was 0.499 for the ORENCIA group and 0.078 for the placebo group (p-value equals 0.0029). The study concluded that the multi-dimensional assessment of independence based on items from commonly used measurement tools (Disease Activity Score 28, Health Assessment Questionnaire Disability Index and SF-36) is viable.

An analysis of the AIM and ATTAIN studies, presented by Wells, et al, examined several different aspects of sleep in RA patients. Sleep quality was assessed using the validated Medical Outcomes Study sleep questionnaire (MOS- sleep). The treatment groups were compared on the seven derived MOS-sleep scales: awakened short of breath or with headache, snoring, sleep adequacy, sleep disturbance, drowsiness, and sleep problems Index I and Index II. Sleep problems Index I and II are summary scores based on the mean of several sleep- related issues, and a higher score indicates more severity in sleep problems.* In addition, the study compared sleep duration and optimal sleep based on the MOS-sleep module.

There was an 18 percent improvement in optimal sleep scores in the ORENCIA(R) (abatacept) group versus -12 percent in the placebo group for the ATTAIN study (p-value less than 0.0001) at six months and a 16 percent improvement in optimal sleep scores in the ORENCIA group versus 5 percent in placebo group for the AIM study (p-value equals 0.0214) at 12 months. Sleep quantity was not significantly different. In the ATTAIN study, measurement of sleep adequacy was 9.0 in the ORENCIA group and 0.6 in the placebo group (p-value equals 0.0028), sleep disturbance was -11.3 in the ORENCIA group and -2.9 in the placebo group (p-value equals 0.0005), drowsiness was -10.5 in the ORENCIA group and -1.6
'/>"/>

SOURCE Bristol-Myers Squibb Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. New Phase 3 Study in Treatment-Naive Adults with HIV Evaluates Efficacy and Safety of Once-Daily PREZISTA(TM)/ritonavir vs. KALETRA(R) as Part of HIV Combination Therapy
2. New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy
3. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
4. Potent Hepatitis C Virus Inhibitors Show Efficacy and Potential for Once Daily Dosing in Preclinical Studies
5. ISTA Pharmaceuticals Presents Results from Two Phase III Clinical Trials of Xibrom(TM) QD (Once-daily) Formulation at the American Academy of Ophthalmology Annual Meeting
6. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
7. R7128 Demonstrates Safety and Potent Antiviral Activity in HCV-Infected Patients
8. Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria
9. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
10. Oritavancin Demonstrates Potent and Rapid In Vitro Activity Against MRSA, VRE and Other Strains of Resistant Bacteria
11. Proteolix Initiates Multicenter Open-label Study of the Safety and Activity of Carfilzomib in Subjects With Relapsed Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... Sept. 1, 2015  AccuTec Blades, Inc. today announced ... Blades division.  EPC announced in May 2015 its intent ... Verona, Virginia and Obregon, Mexico ... sale process. Rick Gagliano , ... Blades said, "Our new name, AccuTec Blades, reflects the ...
(Date:9/1/2015)... --NOWDiagnostics Inc., based in Springdale, Ark. , ... Canada , a move that brings the company ... have greater access to information concerning their health. ... blood-based rapid tests that allow health care providers to ... ailments and diseases. ZBx Corporation, a Toronto ...
(Date:9/1/2015)... DALLAS , Sept. 1, 2015 UT ... and distinguished faculty members joined U.S. Representatives ... in a roundtable discussion on the 21 st ... biomedical research currently being considered by the ... faculty – including National Academy of Sciences members, department ...
Breaking Medicine Technology:AccuTec Blades, Inc. Announces Acquisition of Industrial Blades Division from Edgewell Personal Care Company 2NOWDiagnostics Inc. Acquires Canada's ZBx Corporation 2NOWDiagnostics Inc. Acquires Canada's ZBx Corporation 3U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 2U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 3U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 4U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 5
... Conn., May 15, 2012 /PRNewswire-iReach/ -- Global ... important Cambridge Healthtech Institute conferences: IMVACS – ... August 13 – 15, Cambridge, MA - The ... under one heading: the Seventh Annual Novel Vaccines, Design ...
... Labs, Inc. (OTCQB/OTCBB: GOVX), a biotechnology company that creates, ... results for the three months ended March 31, 2012 ... delighted with recent developments that have strengthened and advanced ... David Dodd. "Our Phase 1/2 therapeutic vaccine trial continues ...
Cached Medicine Technology:Attendees Save up to $350 on CHI Conferences This Summer by Registering Through Global Information 2GeoVax Labs Reports 2012 First Quarter Financial Results 2GeoVax Labs Reports 2012 First Quarter Financial Results 3GeoVax Labs Reports 2012 First Quarter Financial Results 4GeoVax Labs Reports 2012 First Quarter Financial Results 5GeoVax Labs Reports 2012 First Quarter Financial Results 6
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... is proud to announce its new fall collection. Every customer who buys an ... part of the company’s environmental partnership with Trees for the Future, a nonprofit ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... exclusively to funding innovative lymphoma research and serving the lymphoma community through a ... its annual Light it Red for Lymphoma awareness initiative, the nation’s premier and ...
(Date:9/1/2015)... ... , ... From Aug. 17-21, Calvary Hospital hosted the 18th consecutive session of ... has taken place at Kingsborough Community College in Brooklyn in each of the past ... Calvary, and two junior counselors who were campers themselves just a few years ago. ...
(Date:9/1/2015)... ... 01, 2015 , ... Georgia State University and its partners ... in stemming sexual assaults on their campuses. , The free, evidence-based survey was ... assault researchers and student affairs professionals responding to calls by the Obama Administration ...
(Date:9/1/2015)... Eagan, Minnesota (PRWEB) , ... September 01, 2015 ... ... covered health care delivery options, Blue Cross and Blue Shield of Minnesota (Blue ... starting in 2016. , Based in San Francisco, Doctor On Demand provides ...
Breaking Medicine News(10 mins):Health News:Earth Brands Footwear Partners with Trees for the Future for Launch of Fall Collection: Buy Shoes, Plant a Tree 2Health News:Earth Brands Footwear Partners with Trees for the Future for Launch of Fall Collection: Buy Shoes, Plant a Tree 3Health News:Lymphoma Research Foundation Recognizes National Blood Cancer Awareness Month with Light it Red for Lymphoma Campaign 2Health News:Lymphoma Research Foundation Recognizes National Blood Cancer Awareness Month with Light it Red for Lymphoma Campaign 3Health News:Calvary Hospital Hosts 18th Annual Bereavement Camp 2Health News:Calvary Hospital Hosts 18th Annual Bereavement Camp 3Health News:Georgia State, Partners Introduce Climate Survey to Aid in Preventing Campus Sexual Assaults 2Health News:Blue Cross and Blue Shield of Minnesota names Doctor On Demand as preferred telehealth destination 2Health News:Blue Cross and Blue Shield of Minnesota names Doctor On Demand as preferred telehealth destination 3
... Jo-Anne Leese of Cheshire will be refunded ?6000 the amount ... breast cancer treatment.// The amount is to be refunded by ... her treatment. , ,Mrs. Leese got her claims cleared ... provided to patients who wanted Herceptin anti-cancer drug treatment as ...
... A new study reveals that antibiotics if taken limitlessly ... more than 10 times during childhood can increase the ... lymphatic system. , The study, conducted by Ellen ... Centre in Fremont, also found heavy use of non-steroidal ...
... from the Salk Institute for Biological Studies have suggested ... replication is essential for recruiting the //processing machinery that ... ,Telomeres, the ends of linear chromosomes, represent a problem ... damage machinery. An exposed telomere could readily be taken ...
... of people with autism may display autistic brain differences and ... suffer from the disorder themselves. //, ,The ... the annual meeting of the Society of Neuroscience, in Washington ... in Denver, USA. , ,Autism, which affects ...
... Delhi will play host to 800 women from 55 ... Women from November 27. // ,The four-day international ... held for the first time in South Asia. The ... Janeiro (1999) and Stockholm (2002)., ,Among its main ...
... a baby can be detected by his or her eye ... same.// ,Professor Chris Harris, from the University of Plymouth, ... patient's head to see how "flicks" of the eye are ... BBC News. , ,The scientist said: 'The way we ...
Cached Medicine News:Health News:Chromosome Ends Trigger DNA Damage Response For Telomere Protection, 2Health News:Delhi To Host International Women’s Congress From Nov 2 2
Straight shafts with 0.12 mm teeth and tying platform. Serrated handle with polished finish....
Angled 45 degree shafts with 1 x 2 teeth and 5 mm tying platform. Serrated handle with dull finish....
Heavy curved shafts with 2 x 2 teeth and crisscross serrated 6 mm tying platform. Serrated handle with polished finish....
Straight shafts with 1 x 2 teeth and 6 mm tying platform. Wide serrated handle with polished finish....
Medicine Products: