Navigation Links
Post-Hoc Data Show Daily Activity Participation, Independence and Sleep Quality Improved in Adults with Moderate to Severe Rheumatoid Arthritis After Treatment with ORENCIA(R) (Abatacept)
Date:11/12/2007

ate in daily usual activities using a validated activity participation questionnaire. Patients who were treated with ORENCIA were compared with those in the placebo group. This questionnaire was used to assess the number of days in the past 30 days that a patient was unable to perform his or her usual daily activities, defined as paid or unpaid work, household chores or personal care, due to RA. A change of four days in activity participation was deemed to be clinically meaningful.

The percent of patients demonstrating an ability to participate in daily activities in AIM was 61 percent for ORENCIA vs. 46 percent for placebo at one year, and in ATTAIN was 53 percent vs. 32 percent, respectively, at six months. The study found that activity gain was correlated to clinical aspects, physical function and health-related quality of life. In a multi-regression analysis, it was determined that key contributors to activity levels included joint counts, patient global assessment, fatigue, physical function and the physical domains as measured by the Short-Form (SF-36).

A separate analysis of the ATTAIN trial presented by Hassett, et al., examined the incidence of improvement in social role functioning and decreased need for help from others at six months for the ORENCIA group compared to placebo. This was assessed using a multidimensional scale for independence that was derived from validated measures (including the Health Assessment Questionnaire [HAQ], SF-36 and activity participation questionnaire) in which patient physical and social independence were evaluated. After a final analysis, this scale was constructed of two factors: socio-emotional role independence (including SF-36 role-physical, role-emotional, social functioning domains and days with activity limitation) and physical independence (including HAQ items on reach help, care help and ambulating help). Interviews with 20 RA patients confirmed the concept of measuring independence using a multidimensio
'/>"/>

SOURCE Bristol-Myers Squibb Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. New Phase 3 Study in Treatment-Naive Adults with HIV Evaluates Efficacy and Safety of Once-Daily PREZISTA(TM)/ritonavir vs. KALETRA(R) as Part of HIV Combination Therapy
2. New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy
3. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
4. Potent Hepatitis C Virus Inhibitors Show Efficacy and Potential for Once Daily Dosing in Preclinical Studies
5. ISTA Pharmaceuticals Presents Results from Two Phase III Clinical Trials of Xibrom(TM) QD (Once-daily) Formulation at the American Academy of Ophthalmology Annual Meeting
6. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
7. R7128 Demonstrates Safety and Potent Antiviral Activity in HCV-Infected Patients
8. Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria
9. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
10. Oritavancin Demonstrates Potent and Rapid In Vitro Activity Against MRSA, VRE and Other Strains of Resistant Bacteria
11. Proteolix Initiates Multicenter Open-label Study of the Safety and Activity of Carfilzomib in Subjects With Relapsed Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2015)... 2015  AbbVie (NYSE: ABBV ) has announced ... accepted its New Drug Application (NDA) and granted priority ... treatment of ombitasvir, paritaprevir, ritonavir (OBV/PTV/r), with ribavirin (RBV). ... chronic genotype 4 (GT4) hepatitis C virus (HCV) infection. ... therapy being evaluated by the FDA for patients in ...
(Date:4/23/2015)... April 23, 2015 /CNW/ - Health Canada is working ... to update the safety information regarding the risk of ... when these products are used at high doses (at ... and duration of use. Ibuprofen is a ... relief, and to reduce inflammation. The majority of ibuprofen ...
(Date:4/23/2015)... Surna, Inc. (OTCQB: SRNA), a technology company ... and systems for controlled environment agriculture ("CEA") with ... host a shareholder conference call to discuss its ... PM Eastern Standard Time/1:15 PM Pacific Standard Time. ... listen-in only, but will include a Q&A session ...
Breaking Medicine Technology:U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 2U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 3U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 4U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 5U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 6U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 7Information Update - New safety information for prescription-strength ibuprofen: Risk of heart attack and stroke at high doses 2Information Update - New safety information for prescription-strength ibuprofen: Risk of heart attack and stroke at high doses 3Information Update - New safety information for prescription-strength ibuprofen: Risk of heart attack and stroke at high doses 4Surna, Inc. Announces Shareholder Conference Call 2Surna, Inc. Announces Shareholder Conference Call 3
... BEIJING , July 15 /PRNewswire-Asia/ -- Sinovac Biotech ... China , announced today that it,held its 2010 Annual Meeting of ... Beijing Time. The required quorum, a majority of the ... was held,concurrently at No. 39 Shangdi Xi Road, Haidian District, ...
... SUNNYVALE, Calif. , July 15 Premier ... and 67,000-plus other healthcare sites working together to achieve ... provider of FDA-cleared Electronic Brachytherapy Systems, announced the execution ... exclusive three-year contract for brachytherapy systems with Premier Purchasing ...
Cached Medicine Technology:Sinovac Holds 2010 Annual Meeting of Shareholders 2Xoft Announces Exclusive Contract With Premier for Electronic Brachytherapy 2Xoft Announces Exclusive Contract With Premier for Electronic Brachytherapy 3
(Date:4/26/2015)... NC (PRWEB) April 26, 2015 Italian ... the deadly legacy of asbestos cement plants and other ... on the new research. Click here to read ... from Italy’s Department of Occupational and Environmental Medicine analyzed ... 2008 and found 32 clusters where the asbestos cancer ...
(Date:4/26/2015)... Indianapolis, Indiana (PRWEB) April 26, 2015 ... network service provider announces that Brotherhood Mutual Insurance Company ... Daniel Armstrong, Manager of Network Infrastructure at Brotherhood Mutual ... value and the service reliability Brotherhood Mutual needed. ... route diversity, and IFN worked with us to ensure ...
(Date:4/26/2015)... NV (PRWEB) April 26, 2015 From ... Trivedi and his wife, Trivedi Master™ Dahryn Trivedi, spent ... FDA approved research laboratories and institutions in the efforts ... drugs, medicine and nutraceutical supplements for human health care. ... 12 different research labs and institutions. All lab facilities ...
(Date:4/26/2015)... (PRWEB) April 26, 2015 India Network ... in delivering valuable community services to the Asian Indian ... projects in India for more than two decades. The ... and thousands of subscribers around the world with the ... at that time. The Immigration Law Forum Digest, edited ...
(Date:4/26/2015)... Santa Rosa, CA (PRWEB) April 26, 2015 ... researchers from Washington State University evaluated the head-neck biomechanics occurring ... Authors of the study were able to determine that use ... as much as 3 to 5 times - more than ... a surprising outcome for such a study, but pointing out ...
Breaking Medicine News(10 mins):Health News:New Investigation Finds Mesothelioma “Clusters” Around Italian Cement Plants, According to Surviving Mesothelioma 2Health News:Brotherhood Mutual Insurance Company Selects Indiana Fiber Network, LLC for Fiber Transport Service 2Health News:Brotherhood Mutual Insurance Company Selects Indiana Fiber Network, LLC for Fiber Transport Service 3Health News:Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals 2Health News:Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals 3Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 2Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 4
... peers, are key, study finds , , THURSDAY, April 16 ... most important relationships. , But new research shows its ... prevent suicidal behavior in teens who,ve experienced depression or ... high school and a previous suicide attempt were significant ...
... The "Help is Here Express" bus tour will ... - April 24 at various cities in order to help ... prescription medicines for free or nearly free. With the state,s ... of 8.5 percent, the Partnership for Prescription Assistance (PPA) is ...
... the highlights of the annual meeting of the American ... TV quiz shows. , Like a quiz show, Neurobowl ... subtracts points for wrong answers. The tougher the question, ... to diagnose perplexing neurological conditions, based on symptoms, video ...
... To provide greater public access to discussions and deliberations involving ... Americans , the Department of Agriculture today announced that the ... be web-streamed live on April 29th and 30th.A notice regarding ... Federal Register . The Committee will meet on ...
... to expand relationship with healthcare technology solutions providerPLANO, ... and Perot Systems Corporation (NYSE: PER ... an agreement in which Perot Systems will provide ... The multi-year agreement continues TCH,s current relationship where ...
... Nationwide Foundation is making a $1.7 million grant ... affected by disasters and other life-threatening emergencies. This ... contributed this unique grant to the Red Cross.(Logo: ... Nationwide Foundation, an independent corporation funded by Nationwide ...
Cached Medicine News:Health News:Family Ties May Help Prevent Teen Suicide 2Health News:Partnership for Prescription Assistance Prepared to Help Indiana Workers Hurt by Recession 2Health News:Partnership for Prescription Assistance Prepared to Help Indiana Workers Hurt by Recession 3Health News:What do neurologists do for entertainment? 2Health News:2010 Dietary Guidelines Advisory Committee Meeting to Be Webcast April 29th and 30th 2Health News:The Christ Hospital Selects Perot Systems for Revenue Cycle Solutions 2Health News:The Christ Hospital Selects Perot Systems for Revenue Cycle Solutions 3Health News:Nationwide Foundation Donates $1.7 Million to American Red Cross for Disaster Preparedness and Response and Increased Blood Collections 2Health News:Nationwide Foundation Donates $1.7 Million to American Red Cross for Disaster Preparedness and Response and Increased Blood Collections 3Health News:Nationwide Foundation Donates $1.7 Million to American Red Cross for Disaster Preparedness and Response and Increased Blood Collections 4
Comprehensive range of integrated implants and instruments including - Basic, Small, Mini, Pelvic and Foot Sets....
... international engineering and design specifications, Smith ... System* provides seamless integration with existing ... open reduction internal fixational procedures (AO ... well beyond the standard, providing a ...
... has been developed for the transvenous closure ... venous sheaths the device offers a safe ... of ASD's with a super low profile.,A ... twelve arm device for optimal positioning and ...
Stainless steel threaded Steinman Pins available in point types A,D, E, and F....
Medicine Products: