Navigation Links
Positive Xeloda(R) Five-Year Overall Survival Study Data in the Adjuvant Treatment of Colon Cancer Presented at Leading European Cancer Meeting
Date:9/25/2007

phorylase, or TP, Xeloda is transformed into 5-FU, a cytotoxic (cell-killing) drug. Because many cancers have higher levels of TP than does normal tissue, more 5-FU is delivered to the tumor than to other tissue.

Conventional, approved Xeloda dosing on a 14-on/7-off schedule is 1250 mg/m(2) twice daily (total of 2500 mg/m(2)/day).

A clinically important drug interaction between Xeloda and warfarin has been demonstrated; altered coagulation parameters and/or bleeding and death have been reported. Clinically significant increases in prothrombin time (PT) and INR have been observed within days to months after starting Xeloda, and infrequently within one month of stopping Xeloda.

For patients receiving both drugs concomitantly, frequent monitoring of INR or PT is recommended. Age greater than 60 and a diagnosis of cancer independently predispose patients to an increased risk of coagulopathy.

Xeloda is contraindicated in patients who have a known hypersensitivity to 5-fluorouracil, and in patients with known dihydropyrimidine dehydrogenase (DPD) deficiency. Xeloda is contraindicated in patients with severe renal impairment. For patients with moderate renal impairment, dose reduction is required.

The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modification or interruption.

About Roche

Hoffmann-La Roche Inc. (Roche), based in Nutley, N.J., is the U.S. pharmaceuticals headquarters of the Roche Group, one of the world's leading research-oriented healthcare groups with core businesses in pharmaceuticals and diagnostics. For more than 100 years in the U.S., Roche has been committed to developing innovative products and services that address prevention, diagnosis and treatment of diseases, thus enhancing people's health and qua
'/>"/>

SOURCE Roche
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
2. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Protox Announces Positive Clinical Data from Prostate Cancer Study
5. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
6. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
7. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
8. Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... 19, 2014 Five MinuteClinic walk-in medical clinics are opening ... metropolitan area. Three clinics opened in Memphis ... clinic will be added in Springfield on ... is expected to open October 22.  MinuteClinic is the largest ... the United States . The Memphis ...
(Date:9/19/2014)... 19, 2014  Alere Inc. (NYSE: ALR ... following statement today in support of President Barack ... "As the global leader in rapid diagnostics for infectious ... strategy to address the serious threat of antibiotic resistance. ... Administration on initiatives to promote the development of rapid ...
(Date:9/19/2014)... -- BioSpecifics Technologies Corp. (NASDAQ: BSTC ), a biopharmaceutical ... ® in the U.S. and XIAPEX ® in ... , will present a corporate overview at the 21 st ... The presentation will take place on Friday, September ... Hotel in New York, NY . A ...
Breaking Medicine Technology:MinuteClinic Walk-in Medical Clinics Opening in Memphis 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 3Alere Applauds President's Executive Order Combating Antibiotic-Resistant Bacteria 2BioSpecifics Technologies Corp. to Present at the 21st Annual BioCentury NewsMakers in the Biotech Industry Conference 2
... SAN FRANCISCO, Oct. 1 Merriman Curhan Ford Group, ... advisor to TorreyPines Therapeutics, Inc. in the recent merger ... , The combined company is named "Raptor Pharmaceutical Corp." ... NASDAQ Capital Market under the ticker symbol "RPTP." , ...
... PDL BioPharma, Inc. (PDL) (Nasdaq: PDLI ) today announced ... payment of $0.50 per share to all stockholders owning shares ... previously announced, the conversion rate for the Company,s 2.00% Convertible ... shares of common stock per $1,000 principal amount, as a ...
Cached Medicine Technology:Merriman Curhan Ford Acted as Financial Advisor to TorreyPines Therapeutics, Inc. in the Completed Merger With Raptor Pharmaceuticals Corp. 2
(Date:9/20/2014)... September 20, 2014 iFitDress.com, the popular ... for women, has recently unveiled its new collection of ... sale for special offer on these new outfits; it ... season. All customers can now buy cheap cocktail ... company’s sales representative says, “We have extensive experience in ...
(Date:9/20/2014)... The excitement is building up once again for the annual Mayberry ... the Surry Arts Council will be celebrating its 25th year hosting ... still fans of the Andy Griffith Show. , ... from 1960 through 1968. The show ranked by TV Guide ... Airy, North Carolina is where the show was filmed calling it ...
(Date:9/20/2014)... PA (PRWEB) September 20, 2014 "As a ... in their tanks," said an inventor from Tamaqua, Pa. "The ... mounted on the backs of their chairs. My invention enables ... developed the Kam Oxygen Sensor to make it easier to ... that the user knows when the tank is low. It ...
(Date:9/20/2014)... September 20, 2014 Plumbing construction ... out of 5, indicating a moderately favorable purchasing environment ... score reflects current and future pricing trends that will ... prices. Other factors that negatively affect buyer power are ... construction and the moderate switching costs. Buyers benefit, however, ...
(Date:9/20/2014)... QueenBeeTickets.com is ready to offer discount Ariana Grande ... visit many cities in North America next year from ... , Click Here to view the inventory ... The star’s fans are not going to want to ... in a live performance. Ariana Grande concert tickets are ...
Breaking Medicine News(10 mins):Health News:Fashionable Cocktail Dresses Unveiled Online at iFitDress.com 2Health News:Mayberry Days Parade Cars will be Provided by Mount Airy Toyota and Mount Airy Chrysler Dodge Jeep Ram 2Health News:Plumbing Construction Services Procurement Category Market Research Report from IBISWorld Has Been Updated 2Health News:Plumbing Construction Services Procurement Category Market Research Report from IBISWorld Has Been Updated 3Health News:Plumbing Construction Services Procurement Category Market Research Report from IBISWorld Has Been Updated 4Health News:Discount Ariana Grande Tickets: QueenBeeTickets.com Delights Fans with Discount Concert Tickets for Ariana Grande’s 2015 Honeymoon Tour 2
... 4 Nu Skin Enterprises, Inc. (NYSE: NUS ... quarterly dividend of $0.115 per share, which will be paid ... 15, 2009. , , The Company , ... its tradition of innovation through its comprehensive anti-aging product portfolio, ...
... planned benefit changes , , PORTLAND, Ore., June 4 ... perfect storm of rising health care costs and the declining ... three years of predictable rate adjustments and planned benefit changes, ... economic uncertainties. , , In these trying ...
... DIEGO, June 4 NuVasive, Inc. (Nasdaq: NUVA ... minimally disruptive surgical treatments for the spine, announced today that ... to present at the 8th Annual Needham Life Sciences Conference ... York, on Thursday, June 11, 2009, at 11:00 a.m. Eastern ...
... violent relationship may lead to poor mental health, ... --Adults who witnessed parental violence while growing up ... according to researchers who studied 3,023 adults in ... current depression, as well as their experiences with ...
... - , , - Total Net Sales in Line with Previous ... Today at 3:30 pm Central Time - , ... a medical device company that develops, manufactures and markets innovative proprietary products ... and full year ended March 31, 2009. Net sales of $2.9 ...
... is proud to announce the four finalists for its ... a competition to find Minnesota,s most innovative and effective ... cash awards as part of the Engaged Philanthropy Conference ... Graves 601 Hotel in Minneapolis. The Social Entrepreneur,s Cup ...
Cached Medicine News:Health News:Regence Rate Assure(SM) Offers Employer Groups Guaranteed Rates, Benefits 2Health News:NuVasive to Present at the 8th Annual Needham Life Sciences Conference 2Health News:NuVasive to Present at the 8th Annual Needham Life Sciences Conference 3Health News:When Parents Fight, Children Often End Up With Scars 2Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 2Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 3Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 4Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 5Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 6Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 7Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 8Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 9Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 10Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 11Health News:Social Entrepreneur's Cup Finalists Announced 2Health News:Social Entrepreneur's Cup Finalists Announced 3Health News:Social Entrepreneur's Cup Finalists Announced 4Health News:Social Entrepreneur's Cup Finalists Announced 5
... Universal Torso Shoulder Immobilizer A ... 3/8" foam with contact closure. ... posteriorly. Movable wrist cuff. Plastic ... strap. Shoulder strap may adjust ...
... Brace is designed for the functional management ... separations. Using a pre-inflated aircell, the brace ... joint while supporting the arm and shoulder. ... AC Sport Brace for additional arm support ...
... Humerus Fracture Brace indications: , Nonoperative treatment ... Postoperative treatment of open humeral shaft fractures ... , After removal of internal or external ... Defects resulting from tumor growth , ...
Controls humeral segments through soft tissue compression while allowing for full range of elbow motion...
Medicine Products: