Navigation Links
Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Hernia Repair Presented at the Postgraduate Assembly in Anesthesiology (PGA)
Date:12/14/2008

PARSIPPANY, N.J., Dec. 14 /PRNewswire/ -- A Phase II trial of a single intraoperative administration of EXPAREL (DepoBupivacaine) resulted in significantly reduced pain with activity in the first 8 to 24 hours following surgery, when pain is generally greatest, compared to conventional treatment. The results of the multicenter, randomized, double-blind study were presented in a poster at the Annual Postgraduate Assembly in Anesthesiology in New York City today, by lead investigator Richard Langford, MD, FRCA, Pain and Anaesthesia Research Centre, St. Bartholomew's Hospital, London, UK.

Dr. Langford indicated that EXPAREL provided safe and well-tolerated analgesia with normal wound healing in all patients and noted that the study also showed:

-- Significant reductions in pain with activity in EXPAREL treated patients compared to active control

-- A positive trend toward lower opioid use in all EXPAREL groups compared to active control

-- More patients who received EXPAREL avoided opioids altogether, compared to active control.

In addition, the study demonstrated dose-proportional sustained plasma concentrations which support the prolonged local release of bupivacaine.

Presenting the results, Dr. Langford stated, "In addition to significantly lowering pain scores with activity during the 8 to 24 hours after administration, EXPAREL also showed trends of decrease in the number of patients using opioids and a decrease in total opioid consumption. This is an important finding as lowering opioid usage can spare patients from side effects, such as sedation, nausea, vomiting and respiratory depression, that can adversely affect their recovery."

EXPAREL, a proprietary product of Pacira Pharmaceuticals, Inc., is a novel long-acting, sustained-release formulation of bupivacaine HCL, a local anesthetic widely used for treating postoperative pain. The dose-esc
'/>"/>

SOURCE Pacira Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH
2. Positive Phase 1 Clinical Trial Results for Transdermal Lidocaine
3. Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin
4. Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study of Milnacipran for the Management of Fibromyalgia
5. Positive Phase II Study of Paciras EXPAREL(TM) (DepoBupivacaine) in Total Knee Arthroplasty Presented at International College of Surgeons World Congress
6. Kiadis Pharma Announces Positive Clinical Results for ATIR(TM) in Mismatched Bone Marrow Transplantations
7. Third Pivotal Phase 3 Study for NicOx Naproxcinod Shows Positive Efficacy, Safety and Blood Pressure Results
8. Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union
9. Jazz Pharmaceuticals and UCB Announce Positive Phase III Results for Sodium Oxybate (JZP-6) in Fibromyalgia
10. Bionovo Presents Positive Results from Phase 1B Trial of BZL101 for Metastatic Breast Cancer at the Society for Integrative Oncology
11. Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... June 3, 2015 Today, the ... Internet. As markets become ever more transparent, the importance ... AG recognised long ago. Its maxim of "innovation brings ... networking and digitisation. The company has long ... "state of the art" technology and modern approach, while ...
(Date:6/2/2015)... Nevro Corp. (NYSE: NVRO ), a ... solutions for the treatment of chronic pain, today announced ... its common stock at a public offering price of ... of 1,764,705 shares to be sold by Nevro and ... stockholders, resulting in aggregate proceeds of approximately $90.0 million ...
(Date:6/2/2015)... , June 2, 2015  Vanda Pharmaceuticals Inc. (Vanda) ... the development and commercialization of products for the treatment ... Mihael H. Polymeropoulos , M.D., Vanda,s President and CEO, ... Healthcare Conference in New York City ... Eastern Time. The presentation at the Jefferies ...
Breaking Medicine Technology:Nevro Announces Pricing of Upsized Public Offering of Common Stock 2Nevro Announces Pricing of Upsized Public Offering of Common Stock 3
... 8, 2010 California Cryobank (CCB), the ... its newest branch in Indianapolis, IN.  In conjunction with ... (2), New York, Cambridge, and Palo Alto as California ... Woods, PhD., HCLD(ABB), and John Critser, PhD., General BioTech ...
... Fuisz Pharma ( www.fuisz.com ) today announced the issuance ... including same and method for programming same"). ... of glucose and analyte analyzers for home and institutional ... provide better patient care in this era of wireless ...
Cached Medicine Technology:Nation's Leading Sperm Bank Opens Branch in Indianapolis, IN 2Fuisz Announces Issuance of Patent for the New Generation of Glucose and Other Analyte Analyzers 2
(Date:6/2/2015)... “ Radaris ” was featured on NewsWatch ... at the latest and coolest applications on the market for ... and technology expert, conducted the app review and shared with ... on a person. , According to Psychology Today, humans are ... to explain that curiosity is a part of human development. ...
(Date:6/2/2015)... 02, 2015 Tronics, a designer and ... growth strategy to benefit from the significant growth expected ... May 2015 Status of the MEMS Industry report, we ... reach $6.6B in 2020,” says Frederic Breussin, Business Unit ... , The analyst adds that “although the BioMEMS market ...
(Date:6/2/2015)... On October 1, 2015 the transition to ICD-10 ... , On Monday, June 1st Congressman Kevin Brady, ... and Means Committee, and 12 members of the Committee ... Services, urging the administration to provide a smooth transition ... is the newest coding system for healthcare professionals to ...
(Date:6/2/2015)... Erbelli’s Gourmet Pizzeria, Italian Bistro & Pub ... gourmet pizzas and calzones, fresh wraps, submarine sandwiches, and ... the recipes are not—they have been satisfying the taste ... the site is the menu, which is broken up ... the items. You can order directly from the website ...
(Date:6/2/2015)... Claflin Medical Equipment , a Rhode Island ... RSI Equipment, Inc ., a New York ... With CME’s recent merger of Hospital Associates ... organizations which specialize in the procurement and delivery of ... forces, they now cover the entire country with three ...
Breaking Medicine News(10 mins):Health News:A Comprehensive People Search Application Was Featured on NewsWatch Television 2Health News:Tronics Aims to Benefit from Major Growth of Sensors and Related Technologies for Healthcare Applications 2Health News:HomeTown Health Launches a “100 Day Countdown” in Response to ICD-10 Survey 2Health News:HomeTown Health Launches a “100 Day Countdown” in Response to ICD-10 Survey 3Health News:HomeTown Health Launches a “100 Day Countdown” in Response to ICD-10 Survey 4Health News:Erbelli’s of Bradenton Launches New Mobile-Friendly Website 2Health News:Claflin Medical Equipment (CME) Announces Acquisition of RSI Equipment, Inc. 2
... likely than whites, Hispanics to receive all recommended measures, ... Many black patients may not receive the same quality ... patients do, the results of a U.S. study suggest. ... 1,181 hospitals participating in the American Heart Association/Americans Stroke ...
... Citizens from ObamaCare , ... , , ... ... WASHINGTON , March 22 The American ...
... GOOOH Founder Tim Cox said, "Whether you are for ... person in America is disgusted with the politics in Washington ... full of deceit and the policy is laced with disaster . The ... are a perfect example of a system that is broken at best, ...
... ... , ... ... WASHINGTON , March 22 The National Restaurant Association today issued a statement praising passage of a provision that will ...
... ... bicycle , ... 2010 -- Safe Cycling, LLC announced today the addition of a durable, visible and practical ... on the motorist seen side to help remind motorists to give cyclists at least 3 feet ...
... Children,s Health Fund (CHF) strongly supports the health ... its steadfast commitment to this momentous effort.  We believe that ... especially for children.  The action taken shows an unprecedented effort ... well-being of all children in this country.  CHF thanks House ...
Cached Medicine News:Health News:Racial Disparities Persist in Hospital Stroke Care 2Health News:Texas is 39th State to Defend Health Care Choice 2Health News:Texas is 39th State to Defend Health Care Choice 3Health News:GOOOH Declares Disgust With the Politics of Healthcare 2Health News:National Restaurant Association Says Nutrition Information Provision Is Win for Consumers and Restaurants 2Health News:National Restaurant Association Says Nutrition Information Provision Is Win for Consumers and Restaurants 3Health News:New Backpack for Cyclists Sends a Polite Message to Motorists: '3 Feet Please' 2Health News:New Backpack for Cyclists Sends a Polite Message to Motorists: '3 Feet Please' 3Health News:Statement by Irwin Redlener, MD, President, Children's Health Fund on Passage of a Health Care Reform Package by the House 2Health News:Statement by Irwin Redlener, MD, President, Children's Health Fund on Passage of a Health Care Reform Package by the House 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: