Navigation Links
Positive Phase 2 Results Reported with Boehringer Ingelheim's Investigational HCV Protease Inhibitor in Both Previously Treated and Untreated Patients
Date:4/1/2011

BERLIN and RIDGEFIELD, Conn., April 1, 2011 /PRNewswire/ -- New data presented today at the 46th Annual Meeting of the European Association for the Study of the Liver (EASL) demonstrate the antiviral activity of Boehringer Ingelheim's once-daily oral protease inhibitor, BI 201335, in both treatment-naive and -experienced patients with chronic genotype-1 (GT1) hepatitis C virus (HCV), the most challenging genotype of HCV to treat.  Results from SILEN-C1 show a sustained viral response (SVR) in 71 to 83 percent of treatment-naive patients who received BI 201335 once-daily plus the current standard-of-care (SOC) [pegylated interferon (PegIFN) and ribavirin (RBV)].

Results from SILEN-C2 show an SVR in 28 to 41 percent of treatment-experienced patients who received BI 201335 once-daily plus PegIFN and RBV.

"SILEN-C1 and 2 have shown positive Phase 2 results in a broad range of HCV patients," said Peter Piliero, M.D., executive director, Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc. "The current standard-of-care in HCV is not effective for enough patients. Protease inhibitors such as BI 201335 represent potential new options to improve outcomes and the possibility to shorten the duration of treatment for HCV disease."

"Boehringer Ingelheim is continuing its long heritage in virology and commitment to develop new medicines for HCV," continued Piliero. "BI 201335 is part of BI's growing HCV portfolio, which is being investigated with the goal of improving treatment and cure rates for HCV patients.  We are excited that we will commence our Phase 3 trial program with BI 201335 in the near future, based on the results of these Phase 2 studies."

(Oral abstract #60) SILEN-C1: Sustained Virologic Response (SVR) and Safety of BI 201335 Combined with Peginterferon Alfa-2a and Ribavirin in Treatment-Naive Patients with Chronic Genotype-1 HCV InfectionIn this double-blind, randomized, placebo-controlled trial, 429 treatment-na
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6

Related medicine technology :

1. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
2. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
3. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
4. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
5. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
6. NeurogesX Announces Positive Results from Second Phase 3 Clinical Trial in Postherpetic Neuralgia
7. TAXUS WOMAN Study Reports Positive Clinical Outcomes for the TAXUS(R) Drug-eluting Stent in Women
8. Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months
9. Kosans Second-Generation Hsp90 Inhibitor, Alvespimycin, Shows 42% Clinical Benefit in Phase 1 HER2-Positive Metastatic Breast Cancer Trial
10. Pharmacopeia Announces Positive Results from Phase 1 Multiple Ascending Dose Study of PS433540 (DARA)
11. European Unions CHMP Issues Positive Opinion on PEGINTRON(TM) Combination Therapy for Retreating Hepatitis C Patients Who Failed Previous Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... 17, 2013 The power of plants to ... in which mankind depends on the plant kingdom, is ... exhibition Wild Medicine: Healing Plants Around ... view from May 18 through September 8, 2013. ... featured exhibition,s many attractions include a re-creation of the ...
(Date:5/17/2013)... 17, 2013 Medical devices are any medical ... product. In light of their different mechanisms, actions and ... more complicated than drug trails due to their unique ... instead of evaluating both safety and efficacy (which is ... is the same as the SFDA) evaluate MDs for ...
(Date:5/17/2013)... , May 17, 2013  Lakeland Industries, Inc. (NASDAQ: ... protective clothing for industry, healthcare and to first responders ... its financial results for the fiscal 2013 fourth quarter ... 21, 2013 at stock market close and will conduct ... p.m. eastern. (Logo: http://photos.prnewswire.com/prnh/20120611/NY21959LOGO ) ...
Breaking Medicine Technology:Wild Medicine On View at The New York Botanical Garden Through Sept. 8 2Statistical Challenges in Medical Device Trail Evaluation 2Lakeland Industries to Report Fiscal Fourth Quarter and Year End Financial Results and Conduct Conference Call 2
... today announced that Jeff Abbey , the ... of its Arcelis™ dendritic cell-based immunotherapy at 3:30 ... Conference in New York. In addition, Charles ... president of research and development, will participate in a panel ...
... 18 URAC, a leading independent health care quality ... (MRM) program the Bronze Award in Health Information/Decision Support ... Empowerment and Protection Awards. The awards honor programs that ... The Oklahoma Health Care Authority (OHCA) and Oklahoma Department ...
Cached Medicine Technology:Argos Therapeutics to Present Overview of its Arcelis™ Dendritic Cell-based Immunotherapy, Participate in Panel Discussion at Inaugural Cancer Immunotherapy Conference 2Health Care Coordination Program Honored With URAC National Best Practices Award 2Health Care Coordination Program Honored With URAC National Best Practices Award 3Health Care Coordination Program Honored With URAC National Best Practices Award 4
(Date:5/18/2013)... CA (PRWEB) May 18, 2013 The topics ... classes are scrum framework, scrum roles, scrum meetings, scrum artifacts, ... units (8 PDUs) for attending them. , These trainings are ... It is also ideal for those who will be a ... or those who want to explore Agile and Scrum, but ...
(Date:5/18/2013)... According to the the Stevens Johnson Syndrome Foundation, ... is a severe allergic reaction usually to medicine (i). ... can quickly advance causing blistering and large areas of dead ... SJS can develop at any time and seriously affect both ... Manute Bol, passed away after he received kidney medicine which ...
(Date:5/17/2013)... YORK, May 18, 2013. Chronic trauma can inflict lasting ... Previous imaging studies of people with post-traumatic stress disorder, ... over-or under-react in response to stressful tasks, such as ... of a threatening face. Now, researchers at NYU School ... happens in the brains of combat veterans with PTSD ...
(Date:5/17/2013)... Stryker hip lawsuit claims filed ... ABG II Modular-Neck Hip Stem recall continue to move forward ... According to court documents, a Case Management Conference was held ... which time the Court, among other things, set deadlines by ... submit Fact Sheets to Defendant and Liaison Counsel. The ...
(Date:5/17/2013)... Martinson-Nicholls new slip-resistant stair treads ... renovation tread used on steps that require an ... renovation projects, our treads and nosings deliver maximum ... compliment building designs. Bold Step is strong enough ... stairs such as basement or deck steps. , ...
Breaking Medicine News(10 mins):Health News:Affordable Scrum Trainings In Irvine by Conscires Agile Practices 2Health News:Affordable Scrum Trainings In Irvine by Conscires Agile Practices 3Health News:Injury Law Firm Announces New Informative Graphic on Common Medicines That Have Allegedly Been Linked to Stevens Johnson Syndrome 2Health News:For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests 2Health News:Stryker Hip Lawsuit News: Bernstein Liebhard LLP Reports on Recent Case Management Conference in New Jersey Stryker Hip Recall Litigation 2Health News:Stryker Hip Lawsuit News: Bernstein Liebhard LLP Reports on Recent Case Management Conference in New Jersey Stryker Hip Recall Litigation 3Health News:New Bold Step Renovation Stair Treads and Nosings from Martinson-Nicholls Add Slip Resistance to Stairs 2
... , , CHICAGO, July 21 ... new PLEX-ID system currently in development for detecting and characterizing ... in hospitals and other clinical sites. PLEX-ID is the next ... an innovative portfolio of instruments and tests the company is ...
... NORTH HOLLYWOOD, Calif., July 21 /PRNewswire-FirstCall/ -- IPC The Hospitalist ... group practice company, announced today that it will report results for the ... 6, 2009, after the market close. , , ... p.m. ET (2:00 p.m. PT) on August 6, 2009 and will be ...
... survey finds, , TUESDAY, July 21 (HealthDay News) -- Most ... individual health insurance policy on their own never end up ... according to a new study. , A report by the ... health policy reform, found that roughly three of every four ...
... , MINNEAPOLIS, July 21 Norwell VNA ... it has entered into a business relationship with Cardiocom ((R)) ... to patients with chronic illness. Cardiocom, the Experts in ... provider of award-winning telehealth solutions. , , ...
... - (Ocean Nutrition Canada) - These days, consumers ... dollars, buying products that are local, recycled, or ... is literally changing the world: If given the ... from certified sustainable sources, research from the US-based ...
... SAN DIEGO, July 21 The Department of ... the enterprise authentication tool for remote access to VA ... provide more veteran-centric benefit and healthcare services online. ... solution delivered through multiple channels without the cost and ...
Cached Medicine News:Health News:Abbott Introduces Molecular Diagnostic System Intended for Broad Identification of Infectious Agents 2Health News:IPC The Hospitalist Company, Inc. to Report Second Quarter 2009 Results 2Health News:Millions in U.S. Can't Afford Health Insurance 2Health News:Norwell VNA and Hospice Selects Cardiocom Telehealth as Its New Technology Vendor 2Health News:Association of Peruvian Anchovy Producers Pursues MSC Certification 2Health News:Association of Peruvian Anchovy Producers Pursues MSC Certification 3Health News:Association of Peruvian Anchovy Producers Pursues MSC Certification 4Health News:Association of Peruvian Anchovy Producers Pursues MSC Certification 5Health News:Association of Peruvian Anchovy Producers Pursues MSC Certification 6Health News:Department of Veterans Affairs Selects Anakam to Provide Trusted Authentication as Part of Its Overall Identity Management Strategy 2Health News:Department of Veterans Affairs Selects Anakam to Provide Trusted Authentication as Part of Its Overall Identity Management Strategy 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: