Navigation Links
Positive Data for Nektar's New Mu-Opioid Analgesic Molecule to Treat Acute Pain Highlighted at Neuroscience 2011
Date:11/14/2011

SAN FRANCISCO and WASHINGTON, Nov. 14, 2011 /PRNewswire/ -- Nektar Therapeutics (NASDAQ: NKTR) announced today that positive preclinical data for NKTR-192, a novel mu-opioid agonist, was presented at the 41st Annual Meeting of the Society for Neuroscience being held November 12-16, 2011 in Washington, DC.  NKTR-192 is a new oral analgesic candidate being developed for the treatment of acute pain.  It is designed to minimize the unwanted central nervous system (CNS) side effects observed with standard opioid therapies and to reduce abuse liability by slowing the rate of drug entry into the brain.  NKTR-192 is a novel mu-opioid analgesic molecule that was created using Nektar's proprietary polymer conjugate technology and its differentiating properties are inherent to the design of its new molecular structure.  

Approximately 140 million prescriptions are written annually in the U.S. for acute pain indications, such as muscle injuries, post-operative pain, and kidney stones.(1),(2)  Although prescription opioids are considered the most effective treatment for moderate-to-severe pain, their abuse has been identified by the U.S. Food and Drug Administration (FDA) and the Centers for Disease Control (CDC) as a significant public health issue.  The abuse properties of opioid drugs are believed to be related to their rapid rate of entry into the brain.(3)

"NKTR-192 is an exciting new opioid molecule that builds on Nektar's pain platform, which includes NKTR-181, our novel opioid for chronic pain, currently in Phase 1 development," said Rob Medve, M.D., Chief Medical Officer of Nektar Therapeutics.  "NKTR-192 has the potential to offer highly effective short-acting pain relief with a wide therapeutic window, including reduced abuse liability and sedation.  A new opioid analgesic with this compelling profile would be a major advance in th
'/>"/>

SOURCE Nektar Therapeutics
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Ampio Pharmaceuticals Announces Positive Results on Ampion™ Trial for Relief of Nasal Inflammation
2. Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia
3. Sinovac Reports Positive Preliminary Phase II Clinical Trial Results for EV71 Vaccine Against Hand, Foot and Mouth Disease
4. NeuroDerm Announces Positive Results of a Phase II Study of ND0611 Dermal Patch in Patients with Parkinsons Disease
5. Micell Technologies Announces Positive Preliminary Data from DESSOLVE I Study of MiStent® Sirolimus Drug Eluting Coronary Stent System
6. Positive Interim Results from Interferon-Free Phase 2b SOUND-C2 Study with Boehringer Ingelheims Two Investigational HCV Direct Acting Antivirals Presented at AASLD
7. Halozyme Therapeutics Announces Positive Results From Enzyme-Augmented Insulin Pump Trial
8. Positive Phase 2b Results with Sarilumab in Rheumatoid Arthritis to be Presented as a Late-Breaking Poster at the 2011 American College of Rheumatology Annual Meeting
9. Pharmaxis Announces Major Milestone: Positive Bronchitol Opinion for Europe
10. Halozyme Announces Positive Results from Roches Subcutaneous Herceptin Phase 3 Trial
11. Hydrocodone and Oxycodones Lead U.S. General Workforce Positives, Outranked Only by Marijuana, According to Quest Diagnostics Drug Testing Index™
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... 22, 2014 Decision Resources Group finds that by ... to be worth $2 billion (U.S. dollars), increasing at a ... five years (to 2018). This growth comes as ... 2013 and 4.9 percent expected over the next three to ... small but highly competitive. The pharmaceutical market is dominated by ...
(Date:9/22/2014)... YORK , September 22, 2014 ... Market Report on "Global Market Study on Ophthalmic Devices: ... by 2020," the global ophthalmic devices market was valued at USD ... at a CAGR of 6.5% from 2014 to 2020, ... in 2020. Browse the full Global Market Study ...
(Date:9/22/2014)... -- AVT, Inc. (OTC Markets: AVTC) ( www.autoretail.com ), a ... announced today that they are starting production of the ... is designed for placement inside optical shops and Eye ... there are over 20,000 optical stores in America.  ... first automated kiosk dedicated to cleaning and sanitizing eyeglasses ...
Breaking Medicine Technology:Despite Its Limited Size, Chile's Pharmaceutical Market Offers Growing Opportunity for Drug Industry 2Despite Its Limited Size, Chile's Pharmaceutical Market Offers Growing Opportunity for Drug Industry 3Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 2Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 3Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 4Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 5Opticwash Pro Enables Optical Retailers to Generate New Revenues and Customer Traffic through a Unique Eyeglass Cleaning System 2
... MARY, Fla., Jan. 26, 2012   In a pediatric ... caring environment, Middleton Pediatrics is one of the first ... to assess their young patients vision.  This revolutionary vision ... important vision data in one second or less.  ...
... 26, 2012  Aria Diagnostics, a molecular diagnostics company, ... study that examines the accuracy of its non-invasive ... (associated with Down syndrome) and Trisomy 18 (associated ... test, coupled with a proprietary algorithm to assess ...
Cached Medicine Technology:Middleton Pediatrics Now Using Spot to Screen Patients 2Middleton Pediatrics Now Using Spot to Screen Patients 3Aria Announces Publication of Independent Study in the American Journal of Obstetrics & Gynecology Using Aria's Technology 2
(Date:9/22/2014)... have developed a chip capable of simulating a ... system to test the effectiveness of nanoparticles and ... a tumor-microenvironment-on-chip (T-MOC) device, will allow researchers to ... barriers that prevent the targeted delivery of therapeutic ... professor of mechanical engineering., Researchers are trying to ...
(Date:9/22/2014)... Almost three-quarters (74%) of parents are aware of ... one-quarter (28%) have used those online ratings to ... to U-M research published today in Pediatrics ... Mott Children,s Hospital National Poll on Children,s Health, ... of physicians influenced their choices in seeking healthcare ...
(Date:9/22/2014)... 22, 2014 (HealthDay News) -- Metformin, a drug commonly ... low levels of thyroid-stimulating hormone (TSH) among patients with ... researchers cautioned that low TSH levels may be associated ... link was not established in this study. Among ... there were 495 incidences of low levels of thyroid-stimulating ...
(Date:9/22/2014)... 2014 “The Race is On!” for the ... Sunday, October 12, 2014 as it moves to its new ... As the signature fundraising and awareness event for Susan G. ... Phoenix Race for the Cure provides supporters of all ages ... and even sleeping in. , “Moving the Race to ...
(Date:9/22/2014)... A study led by University of North Carolina at ... the accurate diagnosis of people who are experiencing the ... delusions that define the development of severe mental disorders ... early adulthood and affects about 1 in every 100 ... person can be a life compromised, and the burden ...
Breaking Medicine News(10 mins):Health News:New chip promising for tumor-targeting research 2Health News:Online ratings influence parents' choices of physicians for their children 2Health News:Diabetes Drug Metformin May Affect Thyroid in Some Patients 2Health News:22nd Annual Susan G. Komen Phoenix Race for the Cure® 2014 Moves to Downtown Phoenix 2Health News:22nd Annual Susan G. Komen Phoenix Race for the Cure® 2014 Moves to Downtown Phoenix 3Health News:Blood test may help determine who is at risk for psychosis 2
... , , PANAMA CITY, Fla., ... hospital, diligence of staff washing their hands when moving from patient ... The Joint Commission , handwashing failures contribute to ... and cost U.S. hospitals $4 billion to $29 billion annually to ...
... , , MINNEAPOLIS, ... officers, introduced new Board Members and thanked outgoing members for their ... General Counsel, Ltd., was elected as the new Board Chair. The ... , David Fisher, Board ...
... , SAN DIEGO, Sept. 16 ... device company, today announced that its application for premarket approval (PMA) ... approved by the Food and Drug Administration. The Company can now ... , Jim Hitchin, SpectraScience,s, CEO said, "We are pleased ...
... ... supplements at 9th Annual Conference on Protein Expression in Animal Cells (PEACe) in Jackson Hole, ... Fort ... well defined and regulatory friendly cell culture media supplements at the 9th Annual PEACe conference ...
... 16 Prime Staffing, a premier staffing services has achieved ... from The Joint Commission. , , Prime ... national standards addressing how staffing firms determine the qualifications and ... how they monitor staff,s performance. , , ...
... , LONDON, Sept. 16 McGraw-Hill Medical won ... Medical Book Competition awards ceremony, including two category first prize awards ... coveted award went to the ground-breaking Robotic Surgery: Theory and ... , , Speaking about the award, Dr Vivienne ...
Cached Medicine News:Health News:Bay Medical Fights Healthcare-Associated Infections by Improving Hand Hygiene 300% 2Health News:Bay Medical Fights Healthcare-Associated Infections by Improving Hand Hygiene 300% 3Health News:Bay Medical Fights Healthcare-Associated Infections by Improving Hand Hygiene 300% 4Health News:ClearWay Minnesota(SM) Board Approves New Officers 2Health News:SpectraScience Receives FDA Approval for Enhancements to WavSTAT(R) Optical Biopsy System 2Health News:InVitria Cell Culture Product Line to Headline PEACe 2Health News:Prime Staffing Awarded Certification from The Joint Commission 2Health News:McGraw-Hill Medical Wins 2009 BMA Medical Book of the Year Award 2
... with concave seats and large backrests with ... backrests, armrests, and casters and glides. • ... in a variety of environments including: industry, ... care and office. • With reinforced nylon ...
... with concave seats and large backrests with ... backrests, armrests, and casters and glides. • ... in a variety of environments including: industry, ... care and office. • With reinforced nylon ...
... concave seats and large backrests with lumbar ... armrests, and casters and glides. • Choose ... a variety of environments including: industry, education, ... and office. • With reinforced nylon base ...
... chairs with concave seats and large backrests ... seats, backrests, armrests, and casters and glides. ... performance in a variety of environments including: ... health care and office. • With cast ...
Medicine Products: