Navigation Links
Poniard Pharmaceuticals Initiates Randomized Phase 2 Trial of Picoplatin for First-Line Treatment of Metastatic Colorectal Cancer
Date:11/1/2007

nces in 2008.

Poniard is continuing to evaluate picoplatin administered once every two weeks in the FOLPI regimen in its ongoing Phase 1 trial and has not yet reached the maximum tolerated dose for this dosing regimen.

About Picoplatin

Picoplatin has an improved safety profile compared to existing platinum- based chemotherapeutics and was designed to overcome platinum resistance. Poniard's strategy is to develop picoplatin as a platform product that can be used second-line in patients who are resistant or refractory to currently available platinums, such as small cell lung cancer (SCLC) patients, and first-line in patients, such as CRC patients, who cannot tolerate the toxicity profile of currently marketed platinums. We also plan to advance the use of picoplatin in new combination regimens in which platinums are not currently used, such as in the treatment of hormone-refractory prostate cancer (HRPC) patients, in order to improve efficacy. In addition to the Phase 2 trial in metastatic CRC, Poniard is evaluating intravenous picoplatin in an ongoing pivotal Phase 3 trial, known as SPEAR (Study of Picoplatin Efficacy After Relapse), in SCLC. This registrational trial is being conducted under a Special Protocol Assessment (SPA) from the U.S. Food and Drug Administration (FDA) and is evaluating overall survival as the primary endpoint.

The Company is also evaluating intravenous picoplatin in an ongoing Phase 2 trial in combination with docetaxel (Taxotere(R)) and prednisone in patients with metastatic HRPC. Oral picoplatin is being evaluated in a Phase 1 clinical trial in solid tumors.

Picoplatin has been tested in more than 600 patients in Phase 1 and 2 safety and efficacy studies.

About Poniard Pharmaceuticals

Poniard Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative oncology products to impact the lives of people with cancer. Picoplatin, the Company's lead pla
'/>"/>

SOURCE Poniard Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Poniard Pharmaceuticals Announces Promising Data From Interim Safety Analysis of Phase 1 Combination Trials of Picoplatin in Colorectal and Prostate Cancers
2. Poniard Pharmaceuticals Announces Clinical Data from Picoplatin Phase 2 Small Cell Lung Cancer Trial To Be Presented at American Society of Clinical Oncology Annual Meeting
3. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
4. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
5. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
6. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
7. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
8. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
9. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
10. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
11. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... Research and Markets( http://www.researchandmarkets.com/research/d85hx9/global_rapid ) has announced the addition ... - Applications and Technologies" report to their offering. ... estimated at US$19.4 billion in 2014, forecast at US$20.4 ... CAGR of 5.7% between 2014 and 2020 to reach ... global market for Rapid Medical Diagnostic Kits (MDKs) has ...
(Date:5/27/2015)... May 27, 2015 E-QURE, Corp. ... engaged in the development and commercialization of its Bio-electrical ... electrotherapy for the noninvasive treatment of hard to heal ... Zacks Small Cap Research http://scr.zacks.com issued a ... According to Zacks, research update, E-QURE Corp "…has a ...
(Date:5/27/2015)... LONDON , May 27, 2015 ... you trends, partnerships, and predicted revenues   ... manufacturing heading? What are the commercial prospects for ... a whole? Visiongain ,s new report shows you ... opportunities and prospects. Our 203 page report ...
Breaking Medicine Technology:Global Rapid Medical Diagnostic Kits Market - 2015-2020 Applications and Technologies Analysis of the $27 Billion Industry 2Global Rapid Medical Diagnostic Kits Market - 2015-2020 Applications and Technologies Analysis of the $27 Billion Industry 3Global Rapid Medical Diagnostic Kits Market - 2015-2020 Applications and Technologies Analysis of the $27 Billion Industry 4Zacks Investment Small Cap Research Issues Quarterly Update on E-QURE 2Zacks Investment Small Cap Research Issues Quarterly Update on E-QURE 3Medical Device Contract Manufacturing Market Forecast 2015-2025 2Medical Device Contract Manufacturing Market Forecast 2015-2025 3Medical Device Contract Manufacturing Market Forecast 2015-2025 4Medical Device Contract Manufacturing Market Forecast 2015-2025 5Medical Device Contract Manufacturing Market Forecast 2015-2025 6Medical Device Contract Manufacturing Market Forecast 2015-2025 7
... Mich., May 15, 2012  InfuSystem Holdings, Inc. (NYSE MKT: ... related services for the healthcare industry, today announced that ... on Monday, May 21, 2012 following the market close.  ... conference call on Tuesday, May 22, 2012 at 9:00 ...
... 15, 2012 /PRNewswire-iReach/ -- Global Information Inc. ... Drug Development: Contract Research Organizations Market ... at the rate of 12% from 2009 to 2010 ... Contract Research Organizations Market to 2018 : Public-Private Partnerships ...
Cached Medicine Technology:Contract Research Organizations Set to Experience Rapid Growth as Development Costs for New Drugs Continue to Rise 2
(Date:5/27/2015)... Coco Libre announced today that artists and audiences ... Organic Coconut Water to quench their thirst during the festival ... areas, artist greenrooms, corporate skyboxes and concessions areas at the ... on festival shuttle buses. , “We’re excited to have ... Director of Strategic Partnerships for Latitude 38 Entertainment, producer of ...
(Date:5/27/2015)... Cincinnati, Ohio (PRWEB) May 27, 2015 Cincinnati ... Education & Research for Veterans (CERV) Foundation is proud to ... information fair for women Veterans June 11 at the Freedom ... Reporter Karin Johnson will be the emcee. , This ... and devotion to the nation. The banquet is free ...
(Date:5/27/2015)... Phoenix, Arizona (PRWEB) May 27, 2015 ... use of their advanced programmatic marketing technology, they have ... provides advertising support on a regional level for seven ... Honda's marketing was through television and radio media. In ... and, with the help of Genius Monkey , ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 With InnerVoice ... communication environment where the message is not only heard but ... drawing, or virtually any motivating image. This award-winning and affordable ... offer. , Now, using InnerVoice Sender app ... be sent to a learner remotely for no additional cost. ...
(Date:5/27/2015)... Des Moines, Iowa (PRWEB) May 27, 2015 ... time ticking away, a poll conducted during the "ACA ... 200 webinar poll participants, 75% are currently in the ... a little over 15% were confidently prepared for the ... that was shown during the webinar, those who are ...
Breaking Medicine News(10 mins):Health News:Coco Libre Puts Organic Coconut Water on the Line-up at BottleRock Napa 2Health News:Cincinnati VA Women’s Health Clinic Celebrates Women Veterans at Awards Banquet 2Health News:Genius Monkey Boosts Utah Honda Dealers Website Traffic 142% 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 3Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 4Health News:Employers are On Track for ACA Reporting According to Businessolver Poll 2
... body cab decide whether you will be saved from heart disease ... in Costa Rica between 1994 and 2004 were studied and it ... to slowly metabolize caffeine have about a third greater risk of ... a day, and 64 percent increased odds if they had four ...
... threat has receded and with no new case cropped up ... to serve chicken dishes on board.// ,The usual ... with toast were sighted on many flights Wednesday morning. ... poultry back on the list," said Sunil Taneja, director business ...
... signal for the Chennai-based Shasun Chemicals and Drugs Ltd ... the European markets soon. // ,With the ... Agency (MHRA), Shasun's products from its formulation facility in ... European countries. ,Shasun's plant at Pondicherry, set ...
... tried to emphasize the beneficial effects of breast feed over ... obesity during the growing up years. , ,Researchers at ... 90s project, a study that followed the growth and development ... those who were fed formula milk instead of breast milk ...
... languishing in a London hospital, purposefully//, for nearly three years ... by the High court to leave the hospital. ... order which stipulated that he leave Finchley Memorial Hospital in ... eviction, he was also slapped with a charge of ...
... in a statement that a pathogenic form of bird flu ... is Nigeria’s southern most state. ,Idemili, the southern ... and Port Harcourt in Rivers state have been ... culling of infected birds and decontamination of the affected areas ...
Cached Medicine News:
... First Stop absorbable collagen hemostat. FirstStop is ... handling and removal characteristics. It can easily ... fit the wound. FirstStop products are not ... peeled away after hemostasis is achieved. As ...
The VasoSeal Low Profile device is designed for smaller sheath angiography procedures. VasoSeal Low Profile. Seal your arterial punctures with confidence....
... D-Stat Flowable Hemostat has a thick, ... application, such as vascular access sites ... is also used as an adjunct ... tissue tracts of femoral access sites ...
The D-Stat Radial hemostat band utilizes a compression band together with the active haemostatic material of the D-Stat to control surface bleeding....
Medicine Products: