Navigation Links
Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer
Date:5/28/2009

- New Progression-Free Survival, Disease Control and Neurotoxicity Data To Be Presented at 2009 ASCO Annual Meeting Continue to Support Picoplatin as a Neuropathy-Sparing Alternative to Oxaliplatin for First-Line Treatment of Colorectal Cancer -

- Poniard Management Team to Host Analyst and Investor Briefing to Discuss Data on Sunday, May 31st -

SOUTH SAN FRANCISCO, Calif., May 28 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on innovative oncology therapies, today announced updated clinical data from its randomized, controlled Phase 2 trial of picoplatin in patients with metastatic colorectal cancer (CRC). The new data demonstrated that picoplatin, given once every four weeks in combination with 5-fluorouracil and leucovorin in the FOLPI regimen, and oxaliplatin, given in combination with 5-fluorouracil and leucovorin in the modified FOLFOX-6 regimen, have similar anti-tumor activity in the treatment of first-line metastatic CRC, as assessed by progression-free survival (PFS) and disease control measured by tumor response rate. New data derived by three independent assessments of neurotoxicity indicated a statistically significant reduction in neurotoxicities with the use of picoplatin in FOLPI compared with oxaliplatin in FOLFOX (p<0.0019).

"Oxaliplatin given as part of the FOLFOX-based regimen is the current standard of care for metastatic colorectal cancer, but is associated with severe neuropathy at increasing cumulative doses approaching 800 mg/meter squared. This significant side effect may cause patients extreme pain, numbness and weakness, which is often long-lasting and, in many cases, requires patients to discontinue treatment," said Richard Goldberg, M.D., associate director of clinical research for the University of North Car
'/>"/>

SOURCE Poniard Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Poniard Pharmaceuticals Reports First Quarter 2009 Financial Results and Provides a Corporate Update
2. Poniard Pharmaceuticals to Present New Data from Phase 2 Clinical Trials of Picoplatin in Multiple Tumor Types at the 45th Annual Meeting of the American Society of Clinical Oncology
3. Poniard Completes Patient Enrollment Target in Phase 3 SPEAR Trial of Picoplatin in Small Cell Lung Cancer
4. Poniard Pharmaceuticals Reports Fourth Quarter and Year End 2008 Financial Results and Provides a Corporate Update
5. Poniard Pharmaceuticals Announces Management Changes and Focus on Development and Commercialization of Picoplatin
6. Poniard Pharmaceuticals Announces Final Top-Line Results from Phase 1 Trial Demonstrating Positive Bioavailability with Oral Picoplatin
7. Poniard Announces Positive Efficacy and Safety Data From Phase 1 Trial of Picoplatin in Multiple Tumor Types Including Ovarian Cancer
8. Poniard Announces Positive Preliminary Efficacy and Safety Data From Ongoing Phase 2 Trial of Picoplatin in First-Line Treatment of Colorectal Cancer
9. Poniard Announces Positive First-Line Efficacy and Safety Data From Ongoing Phase 2 Trial of Picoplatin in Patients with Metastatic Hormone Refractory Prostate Cancer
10. Poniard to Present Clinical Data From Picoplatin Trials in Multiple Tumor Types at American Society of Clinical Oncology 2008 Annual Meeting
11. Poniard Pharmaceuticals Licenses Kinase Inhibitors From The Scripps Research Institute
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/27/2014)... , Oct. 27, 2014  RenovoRx, a leading ... flow and delivery of fluids to selected sites in ... of Directors has appointed Shaun Bagai as ... the RenovoRx Board of Directors. Bagai brings more than ... Bagai joined RenovoRx in June 2014 and ...
(Date:10/27/2014)... , Oct. 27, 2014  In the last few weeks, ... Africa to a worldwide crisis when a ... the virus and died, and two nurses were infected. ... could happen, the use of modern technology, such as electronic health ... unnoticed. This week, InformationWeek Healthcare Editor Alison Diana ...
(Date:10/27/2014)... Research and Markets has announced ... 2014-2018" report to their offering. ... a variety of tasks that might be simple or ... into two broad divisions: Professional Robot and Personal/domestic Robot. ... challenging environment such as underwater applications, defense, and security ...
Breaking Medicine Technology:RenovoRx Board Names Shaun R. Bagai as CEO 2EHRs in the Age of Ebola: Discuss on InformationWeek 2EHRs in the Age of Ebola: Discuss on InformationWeek 3Global Service Robot Market 2014-2018: Key Vendors are GeckoSystem, Honda Motor, iRobot and Toyota Motor 2Global Service Robot Market 2014-2018: Key Vendors are GeckoSystem, Honda Motor, iRobot and Toyota Motor 3
(Date:10/30/2014)... (PRWEB) October 30, 2014 Nutrition Leaders, ... supplements, weight loss aids, and more, is currently hosting ... which is already underway, is open to U.S. residents ... on December 15, 2014. One lucky winner will then ... receive a $100 gift card to NutritionLeaders.com. , Nutrition ...
(Date:10/30/2014)... 2014 Don Allred Insurance, a leading ... plans for North Carolina residents, is excited to announce ... Holly Hill Mall. The new branch has been up ... customers through all facets of the insurance selection process ... spokesman Scott Allred couldn’t be happier with the timing ...
(Date:10/30/2014)... 2014 PreDiabetes Centers , the ... shoppers with a supply of sugardown®, a chewable ... post-meal blood sugar spikes. Learning how to control blood ... part of a diabetes prevention plan. , Shoppers who ... complimentary tube of sugardown. The offer expires November 30. ...
(Date:10/30/2014)... Steven Reinberg HealthDay Reporter ... therapy to men with prostate cancer who also have certain ... heart-related cause, a new study suggests. , , The therapy in ... prostate cancer to reduce levels of male hormones to prevent ... in the current research, this hormone therapy was linked to ...
(Date:10/30/2014)... Home Care Assistance – Halton/Peel Region ... in-home senior care, is weighing in on a recent ... The study, performed by the University of Illinois, analyzed ... over a week-long period and observed how much time ... By examining the structural soundness of the white matter ...
Breaking Medicine News(10 mins):Health News:Nutrition Leaders Announces Gift Card Sweepstakes 2Health News:Allred Insurance Satellite Office Grand Opening 2Health News:PreDiabetes Treatment Company Offers PreD Store Shoppers Supplements to Support Healthy Blood Sugar 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 3Health News:Home Care Assistance – Halton/Peel Region, a Top Provider of In-Home Care, Responds to Study Linking Exercise to Healthier Senior Brains 2Health News:Home Care Assistance – Halton/Peel Region, a Top Provider of In-Home Care, Responds to Study Linking Exercise to Healthier Senior Brains 3
... emotional toll on unemployed, families, even those still working, , , ... more bad news on the U.S. economic crisis, the monetary ... to measure than the mental toll on the thousands of ... you lose a job, the losses are multiple," explained Michael ...
... Publishes Letter Outlining Strategy, Market Opportunity and New ... Inc. (OTC Bulletin Board: MCLN), a provider of ... and disposal of regulated medical waste, today announced ... published a letter to shareholders. The letter, ...
... All-Star Chris Paul and WNBA,All-Star Diana Taurasi, are teaming ... a new national campaign called Get Fit By Finals. ... All-Star 2009 in Phoenix, Ariz., is,part of a new ... and,NBA FIT, the NBA,s comprehensive health and wellness initiative ...
... Observance To Draw Attention To "The Sneak Thief of Sight" ... effort to combat one of the leading causes of blindness ... Organization have set March 12, 2009, as the second ... by awareness and educational events organized by eye care institutions ...
... brings extensive experience in neuroscience and oncology to ... therapeutic categories , , ROCKVILLE, Md. ... Pharmaceutical, Inc. (OAPI), a fast-growing health care company ... North America, has announced the appointment of Mark ...
... ROCKVILLE, Md., Feb. 12 Neuralstem, Inc. (NYSE ... former Senator (D-Tennessee) and former Ambassador to the ... Advisory Board and will serve as senior advisor ... was elected to the United States Senate from ...
Cached Medicine News:Health News:Job Losses Carry High 'Stress Tag' 2Health News:Job Losses Carry High 'Stress Tag' 3Health News:Job Losses Carry High 'Stress Tag' 4Health News:MedClean Technologies Inc. CEO Publishes Letter to Shareholders 2Health News:The NBA Teams up With Body By Milk to Challenge Teenagers to 'Get Fit By Finals' 2Health News:The NBA Teams up With Body By Milk to Challenge Teenagers to 'Get Fit By Finals' 3Health News:The NBA Teams up With Body By Milk to Challenge Teenagers to 'Get Fit By Finals' 4Health News:The NBA Teams up With Body By Milk to Challenge Teenagers to 'Get Fit By Finals' 5Health News:World Glaucoma Day Set For March 12, 2009 2Health News:World Glaucoma Day Set For March 12, 2009 3Health News:World Glaucoma Day Set For March 12, 2009 4Health News:Otsuka America Pharmaceutical, Inc. Announces the Appointment of Mark Altmeyer as President and Chief Executive Officer 2Health News:Otsuka America Pharmaceutical, Inc. Announces the Appointment of Mark Altmeyer as President and Chief Executive Officer 3Health News:Otsuka America Pharmaceutical, Inc. Announces the Appointment of Mark Altmeyer as President and Chief Executive Officer 4Health News:Otsuka America Pharmaceutical, Inc. Announces the Appointment of Mark Altmeyer as President and Chief Executive Officer 5Health News:Otsuka America Pharmaceutical, Inc. Announces the Appointment of Mark Altmeyer as President and Chief Executive Officer 6Health News:Senator James Sasser, Former Ambassador to China, Joins Neuralstem Advisory Board 2Health News:Senator James Sasser, Former Ambassador to China, Joins Neuralstem Advisory Board 3
... is enzyme immunoassay kit for the ... concentration in serum. Enzyme immunoassay (EIA) ... many protein hormones in body fluids ... rapid and specific assay. This enzyme ...
SHIONORIA BNP,is a reagent used in the measurement of blood BNP. The blood BNP test allows accurate estimation of coronary functions....
... method for the semi-quantitative determination of ... human serum. The results of the ... an aid in the diagnosis of ... with elevated anti-neutrophil cytoplasmic antibodies (P-ANCA) ...
... The determination of Ang ... in monitoring the pharmacological effect ... variety of angiotensin converting enzyme ... II receptor antagonists as well ...
Medicine Products: