Navigation Links
Poniard Announces Positive Preliminary Efficacy and Safety Data From Ongoing Phase 2 Trial of Picoplatin in First-Line Treatment of Colorectal Cancer
Date:6/1/2008

- Phase 2 Data To Be Presented Along With Updated Phase 1 Colorectal Cancer

Data at ASCO Annual Meeting -

SOUTH SAN FRANCISCO, Calif. and CHICAGO, June 1 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on oncology, today announced positive preliminary results from its ongoing randomized Phase 2 clinical trial in patients with metastatic colorectal cancer (CRC) and updated results from an ongoing Phase 1 CRC trial. Preliminary data suggest that picoplatin given in combination with 5-fluorouracil and leucovorin (FOLPI) and oxaliplatin given in combination with 5-fluorouracil and leucovorin (FOLFOX) may have similar anti-tumor activity in metastatic CRC.

The Company will present the Phase 1 and 2 picoplatin data (abstract #4100) in the General Poster Session during the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO) at McCormick Place in Chicago. Picoplatin, the Company's lead product candidate, is a new generation platinum chemotherapy agent with the potential to become a platform product addressing multiple indications, combinations and formulations for the treatment of multiple solid tumor indications.

"The comparison of picoplatin and oxaliplatin in combination with 5-fluorouracil and leucovorin has provided encouraging preliminary results," said Robert De Jager, M.D., chief medical officer of Poniard. "These data support our strategy of developing picoplatin as a preferred platinum for the first-line treatment of metastatic CRC. The ongoing Phase 2 trial could support advancement of picoplatin into a registration trial."

Phase 2 CRC Study Preliminary Results

The randomized, controlled, 100-patient P
'/>"/>

SOURCE Poniard Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

2

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Poniard Pharmaceuticals to Present Updated Results of Picoplatin Phase 2 Small Cell Lung Cancer Trial at 12th World Conference on Lung Cancer
2. Poniard Pharmaceuticals Announces Updated Results of Picoplatin Phase 2 Trial Demonstrating Survival Benefit in Small Cell Lung Cancer Patients
3. Poniard Pharmaceuticals Receives FDA Fast Track Designation for Picoplatin for Treatment of Small Cell Lung Cancer
4. Poniard Pharmaceuticals Initiates Randomized Phase 2 Trial of Picoplatin for First-Line Treatment of Metastatic Colorectal Cancer
5. Poniard Pharmaceuticals Provides Year-End Clinical Update at 2007 Lazard Capital Markets Healthcare Conference
6. Poniard Pharmaceuticals Announces Picoplatin Safety Data in Colorectal Cancer
7. Poniard Pharmaceuticals Announces Positive First-line Phase 1 Safety and Efficacy Data With Picoplatin in Metastatic Prostate Cancer Patients
8. Poniard Pharmaceuticals Announces Clinical Data From Picoplatin Oral Phase 1 to Be Presented at the American Association of Cancer Research Annual Meeting
9. Poniard Pharmaceuticals Announces Commercial Manufacturing Agreement With W. C. Heraeus GmbH for Picoplatin
10. Poniard Pharmaceuticals Announces Presentation of Clinical Data From Picoplatin Phase 2 Small Cell Lung Cancer Trial to be Presented at 1st IASLC-ESMO European Lung Cancer Conference
11. Poniard Pharmaceuticals Oral Picoplatin Demonstrates Positive Bioavailability in Ongoing Phase 1 Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... , May 23, 2013  Inhibikase Therapeutics, Inc., ... today that it will present new results on ... industry conference sponsored by the PML Consortium (composed ... JC polyomavirus (JCV) is the causative agent of ... kinase inhibitor in an extended release formulation, can ...
(Date:5/23/2013)... 23, 2013  PAREXEL International Corporation (NASDAQ: ... at the Jefferies Healthcare Conference in New York.  ... Chief Financial Officer, will be making a presentation on ... Monday, June 3, 2013. A live webcast ... section of PAREXEL,s website at www.PAREXEL.com in ...
(Date:5/22/2013)... , May 22, 2013  Aribex, Inc., manufacturer ... system, today introduced a new color option, black with ... U.S. dental and veterinary markets. The popular white with ... month will continue to be available and both models ... (Photo: http://photos.prnewswire.com/prnh/20130522/CL19573 ) ...
Breaking Medicine Technology:Inhibikase Therapeutics to present at Industry Conference on Drug-Induced Progressive Multifocal Leukoencephalopathy (PML) 2PAREXEL International To Present At Jefferies Healthcare Conference 2Aribex Unveils New Color of NOMAD Pro 2 2
... 2011  Proventix Systems, Inc., today announced its nGage™ ... hand hygiene monitoring system in the United States.  ... total hand cleansings. Hospitals have experienced ... dispenses since implementation of the Proventix monitoring system. ...
... brings a whole set of skin problems for many people, ... Americans who suffer from psoriasis. Cold weather, dry indoor heat, ... rob the skin of the moisture it needs, causing psoriasis ... system, making it harder for the body to resist psoriasis ...
Cached Medicine Technology:Proventix's nGage™ the Most Widely Used Automated Healthcare Hand Hygiene Monitoring System in the United States 2Proventix's nGage™ the Most Widely Used Automated Healthcare Hand Hygiene Monitoring System in the United States 3PhotoMedex Helps Psoriasis Patients Ease Winter Skin Care Woes 2PhotoMedex Helps Psoriasis Patients Ease Winter Skin Care Woes 3PhotoMedex Helps Psoriasis Patients Ease Winter Skin Care Woes 4
(Date:5/23/2013)... May 23, 2013 NDI Medical, ... and develops innovative neurodevice technologies, has launched its ... DBI will commercialize its groundbreaking technology that ... therapy for patients with Parkinson’s disease. Currently ... disease and generates more than $275 million in ...
(Date:5/23/2013)... PETA International Science Consortium, Ltd., issued the following ... of 2013: , Reform of chemical safety legislation ... testing. , Ensuring the safety and appropriate ... Reforming the EPA,s Toxic Substances Control Act is ... Council,s vision for transforming toxicity testing "from a ...
(Date:5/23/2013)... Dotinga HealthDay Reporter , , WEDNESDAY, May 22 (HealthDay ... scans for detecting lung cancer now have more information to ... U.S. study finds that low-dose CT scans pick up significantly ... a long history of smoking are at high risk for ... States. But doctors have to consider the potential harm of ...
(Date:5/23/2013)... In Florida, residents have not been hit with a ... Florida’s good luck will continue, warns Rick Knabb, Director of ... residents, it is important to prepare as if one could ... to be a 50-percent chance that a major hurricane could ... from June 1 to November 30 in Florida, this makes ...
(Date:5/23/2013)... Award-winning parent coaching and training ... ImpactADHD’s six-part Parent Academy Mastery Series gives families ... challenges of raising ADHD kids head-on. Parenting kids ... frustrating. It can also be joyful and positively ... and the ‘good stuff’ is all-too-often out of ...
Breaking Medicine News(10 mins):Health News:NDI Launches Deep Brain Innovations, LLC 2Health News:NDI Launches Deep Brain Innovations, LLC 3Health News:CT Scans Reduce Lung Cancer Deaths, Study Confirms 2Health News:CT Scans Reduce Lung Cancer Deaths, Study Confirms 3Health News:As Hurricane Season Nears, Skylake Insurance Encourages Florida Residents To Prepare Early For Safety 2Health News:New Approach to ADHD Managment Focuses On Parents, Not Kids 2
... while sticking to your diet. Here,s how. , FRIDAY, Dec. 25 ... you,ve eaten and that box of Santa Claus-shaped candies is calling ... overeat and overindulge aren,t over yet. , Before you take one ... to get a handle on your holiday eating. , If you,ve ...
... how product is designed, study shows , THURSDAY, Dec. ... everything from promoting youth violence to contributing to childhood obesity, ... planned on passing by the video game aisle this holiday ... can sharpen certain thinking skills, increasing cognitive speed in those ...
... Dec. 24 Today, The U.S. Conference of Mayors (USCM) congratulates ... health care for millions of the uninsured. In a historic ... the Patient Protection and Affordable Care Act. , "Not ... on Christmas Eve. It is appropriate the most important ...
... THURSDAY, Dec. 24 (HealthDay News) -- Acetaminophen -- best ... physical pain, but a new study suggests that the ... of rejection. , Researchers assigned 62 healthy college undergraduate ... 1,000 milligrams of acetaminophen daily, while the others took ...
... , ... (PhRMA) Senior Vice President Ken Johnson released the following statement ... the Senate for taking an important and historic step toward ... of millions of Americans, many of whom are struggling today ...
... , , WASHINGTON, Dec. 24 ... Senate voted to pass the Patient Protection and Affordable Care ... bill on Christmas Eve, after overcoming a series of procedural ... stop the bill from ever reaching the Senate floor for ...
Cached Medicine News:Health News:Eat Up, But Eat Healthy This Holiday Season 2Health News:Video Games Could Boost Certain Thinking Skills 2Health News:Video Games Could Boost Certain Thinking Skills 3Health News:Tylenol May Ease Headaches and Heartaches 2Health News:Tylenol May Ease Headaches and Heartaches 3Health News:PhRMA Statement on Senate Health Care Reform Bill 2Health News:PhRMA Statement on Senate Health Care Reform Bill 3Health News:DNC Chairman Tim Kaine Calls Senate Vote Historic, Says Landmark Health Reform Bill Is a Victory for the American People 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: