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PneumRx, Inc.'s RePneu Coil Becoming Therapy of Choice for Patients with Severe Emphysema
Date:9/26/2013

y lung tissue, but instead provides a simple mechanical solution designed both to treat the key physiologic effects of emphysema and to overcome the key challenges of emphysema treatment.  As evidenced by the data presented at the recent European Respiratory Society (ERS) meeting in Barcelona, Spain, the RePneu Coil is unique in its ability to treat patients with both heterogeneous and homogeneous emphysema, in both upper and lower lobes, in patients with Residual Volume of 175% predicted and above.  In addition, the RePneu LVRC works independently of collateral ventilation, and is performed in a gentle, well-tolerated procedure with a rapid recovery period.

The RePneu Coil is also used extensively in the Netherlands and the UK.  Dr. Dirk-Jan Slebos, of the University Medical Center, Groningen, the Netherlands, has implanted over 1,000 Coils in emphysema patients and is expected to treat 40 subjects this year in the  315-subject, multicenter pivotal study, RENEW, the results of which will be submitted for commercial approval of the RePneu LVRC in the US.   Also participating in the RENEW Study is Dr. Pallav Shah of the Royal Brompton and Hareford National Hospital Trust and the Chelsea and Westminster National Hospital Trust in London, U.K.  Dr. Shah previously participated in a multi-center, randomized, controlled study of the LVRC in the UK (the RESET Study), the results of which were published this year in The Lancet Respiratory.  Among the findings in that study, subjects treated with the RePneu LVRC showed statistically and clinically significant improvements in exercise capacity (6MWT), lung function (FEV1, Residual Volume), and quality of life (SGRQ) as compared to subjects who received best medical care, but no LVRC procedures.  In particular, subj
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