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Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs
Date:9/15/2008

New Treatment May Revolutionize Care for Patients With Deep Vein Thrombosis; $10 Million National Institutes of Health ATTRACT Study To Determine if Drug- Device Technique Can Prevent Post-Thrombotic Syndrome

FAIRFAX, Va., Sept. 15 /PRNewswire-USNewswire/ -- ATTRACT -- the first major national trial of a catheter-based treatment for deep vein thrombosis -- will evaluate the use of clot-dissolving drugs in combination with clot removal devices to prevent post-thrombotic syndrome in patients with DVT (the formation of a blood clot in a leg vein). PTS, a common irreversible complication of DVT, causes permanent damage to the veins, resulting in debilitating chronic leg pain, swelling, fatigue and/or skin ulcers. About 25- 50 percent of DVT patients develop PTS when treated with blood thinners alone. While early treatment with blood thinners is important to prevent a life- threatening pulmonary embolism, blood thinners alone do not dissolve the existing clot, which remains in the leg. Preliminary studies have shown that interventional clot-busting treatments can -- unlike standard DVT therapy -- remove clots and have strong potential to prevent PTS. The outcomes of this pivotal multicenter trial -- to be funded at more than $10 million by the National Institutes of Health's National Heart, Lung and Blood Institute (NHLBI) -- are likely to change the way DVT is treated in the United States.

"The ATTRACT trial could fundamentally shift the 50-year-old DVT treatment paradigm to one that includes interventional clot removal as an essential element of standard DVT care," said interventional radiologist Suresh Vedantham, M.D., who will lead the trial. "By funding this study, the NHLBI has clearly recognized the strong potential of interventional radiology clot removal treatments for DVT to improve public health," added the associate professor at the Washington University School of Medicine's Mallinckrodt Institute of Radiology in St. Louis, Mo. '/>"/>

SOURCE Society of Interventional Radiology Foundation
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