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Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD
Date:10/29/2008

lung diseases -- emphysema and chronic bronchitis -- which result in decreased quality of life, chronic airway inflammation and progressive loss of lung function, making it difficult to breathe normally.(8) Common symptoms include shortness of breath, chronic cough, wheezing and excess mucus.(8) In patients with severe to very severe COPD, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends the addition of inhaled corticosteroids (ICS) to long-acting beta2-agonists (LABA), in addition to other treatment options, to reduce exacerbations and improve lung function and health status.(9) COPD is a progressive disease, which means people with COPD can expect lung function to worsen over time.(9) When symptoms are severe, it can be difficult for a person to perform simple, daily tasks.(8) As the disease progresses, people with COPD may eventually require supplemental oxygen and may ultimately have to rely on mechanical ventilatory assistance.(10)

About SYMBICORT

SYMBICORT is a combination therapy indicated for the long-term maintenance treatment of asthma in patients 12 years of age and older.(6) SYMBICORT is not indicated in patients whose asthma can be successfully managed by inhaled corticosteroids along with occasional use of inhaled short-acting beta2- agonists.(6) Administered twice daily,(6) SYMBICORT is a combination of two proven asthma medications-budesonide, an inhaled corticosteroid (ICS), and formoterol, a rapid and long-acting beta2-agonist (LABA).(6) SYMBICORT does not replace fast-acting inhalers and should not be used to treat acute symptoms of asthma.(6)

Important Safety Information

Long acting beta2-adrenergic agonists may increase the risk of asthma-related death. Therefore, when treating patients with asthma, SYMBICORT should only be used for patients not adequately controlled on other asthma-controller medications (e.g., low-to-medium dose inhaled corticosteroids) or whose disease severity clearly w
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SOURCE AstraZeneca
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