Navigation Links
Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD
Date:10/29/2008

CLA). "Data from these trials also showed that a greater percentage of patients achieved a 15 percent improvement in FEV1 within 15 minutes with SYMBICORT as compared to budesonide and placebo on the day of randomization and end of treatment."(5)

SHINE Study Results (Abstracts 298 and SHINE Safety)

The efficacy and tolerability of SYMBICORT was assessed in a six-month, randomized, double-blind, multicenter trial evaluating 1,704 patients ages 40 years and older with moderate to very severe COPD.(1,2) After two weeks of treatment based on previous therapy (inhaled corticosteroids (ICS) and short-acting bronchodilators were allowed), patients were then randomized to receive twice-daily treatment with two inhalations of SYMBICORT pMDI 160/4.5 micrograms (mcg), SYMBICORT pMDI 80/4.5 mcg, budesonide pMDI 160 mcg + formoterol DPI 4.5 mcg, budesonide pMDI 160 mcg, formoterol DPI 4.5 mcg or placebo.(1,2) Study results include:

-- Both SYMBICORT doses (160/4.5 and 80/4.5 mcg) demonstrated a significantly greater improvement from baseline in pre-dose forced expiratory volume in one second (FEV1) (P Less Than or Equal To .001) and one-hour post-dose FEV1 compared with budesonide (P<.001).(1)

-- SYMBICORT 160/4.5 mcg also demonstrated a significant (P=.026) improvement from baseline for pre-dose FEV1 compared with formoterol.(1)

-- Improvements from baseline in morning and evening peak expiratory flow (PEF) were significantly (P Less Than or Equal To .016) greater for both SYMBICORT doses compared with formoterol, budesonide and placebo.(1)

-- Both SYMBICORT doses significantly (P<.028) improved the sum of Breathlessness, Cough and Sputum Scores (BCSS), sleep score, awakening-free nights, and rescue medication use versus placebo.(1)

-- Both doses of SYMBICORT were well-tolerated for six months relative to its monocomponents and placebo.(2) The incidence of pneumonia-related adverse events were similar for all treatment arms compa
'/>"/>

SOURCE AstraZeneca
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Pivotal Phase III Data Confirm the Efficacy and Safety of Arpidas Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections
2. Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)
3. Neurobiological Technologies Announces FDA Agreement to Consolidate Viprinex Phase 3 Trials Accelerating Time to Pivotal Data
4. SCOLR Pharma Announces Completion of Patient Enrollment and Dosing for Pivotal Clinical Trial Evaluating Extended Release Ibuprofen
5. Recruitment Completed in Ofatumumab NHL Pivotal Study
6. Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs
7. NicOx Announces Second Naproxcinod Pivotal Phase 3 Study (302) Meets Efficacy Primary Endpoints and Supports Non-Detrimental Blood Pressure Effect
8. Alpharma Announces Positive Results From Pivotal Phase III Efficacy Trial on ALO-01 (EMBEDA(TM)) (morphine sulfate extended-release with sequestered naltrexone hydrochloride) Capsules at the American Academy of Pain Management Annual Clinical Meeting
9. 338 Patient Pivotal Trial Demonstrates Safety and Effectiveness of Polidocanol Sclerotherapy Product for Varicose Vein Treatment
10. Second Pivotal Phase 3 Trial In Cystic Fibrosis Begins
11. First DuraHeart(TM) Left Ventricular Assist System Implanted in the U.S. Pivotal Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... , Aug. 1, 2014 In the ... treatments for sexual dysfunction, more than 60 doctors and ... an open letter questioning the Food and Drug Administration,s ... most common form of male sexual dysfunction compared with ... the agency to act for women by approving the ...
(Date:8/1/2014)... HAZLET, N.J. , Aug. 1, 2014 Aspire ... Customer Satisfaction Excellence Gold Star from Cisco. This designation recognizes ... the United States of America . ... culture," stated John C. Harris , President and CEO ... to our customers with their Gold Star award and are ...
(Date:8/1/2014)... 2014 MGC Diagnostics Corporation (NasdaqCM: MGCD), ... that it has completed its acquisition of MediSoft ... products based in Sorinnes, Belgium ... cardiorespiratory diagnostics market since 1977. MediSoft, a calendar ... million ($6.3 million) and incurred a net loss ...
Breaking Medicine Technology:60+ Healthcare Professionals Sign an Open Letter Urging the FDA to Approve First-Ever Drug to Treat Women's Most Common Form of Sexual Dysfunction, notes Even the Score 260+ Healthcare Professionals Sign an Open Letter Urging the FDA to Approve First-Ever Drug to Treat Women's Most Common Form of Sexual Dysfunction, notes Even the Score 3Aspire Technology Partners Recognized By Cisco For Excellence In Customer Satisfaction 2MGC Diagnostics Corporation Completes Acquisition of MediSoft SA 2MGC Diagnostics Corporation Completes Acquisition of MediSoft SA 3MGC Diagnostics Corporation Completes Acquisition of MediSoft SA 4
... 4 Shared Imaging, LLC, an independent provider of ... hospitals and healthcare providers, is excited to announce it ... Care, a nationally-recognized, prestigious gold seal of approval for ... is system-wide for its mobile MRI and PET/CT services. ...
... , LAKE FOREST, Ill., Dec. ... global specialty pharmaceutical and medication delivery company, today announced the launch ... intravenous (I.V.) medications and solutions, and now offers a complete size ... VisIV product. The launch of the 50 mL and 100 mL ...
Cached Medicine Technology:Shared Imaging Earns The Joint Commission's Accreditation for Ambulatory Health Care 2Hospira Expands VisIV(TM) Portfolio to Offer Complete Range of Environmentally Friendly I.V. Containers 2Hospira Expands VisIV(TM) Portfolio to Offer Complete Range of Environmentally Friendly I.V. Containers 3Hospira Expands VisIV(TM) Portfolio to Offer Complete Range of Environmentally Friendly I.V. Containers 4
(Date:8/1/2014)... 01, 2014 As AndroGel lawsuits and ... Ronald E. Johnson, Jr. has been appointed as co-lead ... other testosterone medications. Since the Fall of 2013, Ron ... worked diligently to investigate and prosecute the claims of ... blood clots as a result of taking testosterone. As ...
(Date:8/1/2014)... Texas (PRWEB) August 01, 2014 ... health coverage and healthcare reforms are boosting healthcare ... of medicines through discounts and increasing generic consumption ... at approximately 76.7 million in 2013, having grown ... 1.4%, from 2008. The implementation of the Health ...
(Date:8/1/2014)... 01, 2014 The "Antimicrobial Coatings ... as Zinc Oxide, Titanium Dioxide, and Zinc Omadine), ... Construction, Food & Beverages, Textiles, and others), & ... Global Trends and Forecasts to 2018" analyzes the ... opportunities, and trends in the diverse geographical regions. ...
(Date:8/1/2014)... According to new market research report "Automotive Exhaust ... & ROW), by Vehicle Type (Passenger Cars, LCVs, ... by After-Treatment Device (DPF, DOC, SCR, TWC, & ... defines and segments the global automotive exhaust systems ... all the regions, and estimates their exhaust systems ...
(Date:8/1/2014)... NY August 1, 2014 The Cardiovascular ... and first report investigations that will be presented ... scientific symposium. TCT, the world,s premier educational meeting ... September 13 17, 2014 at the Walter ... Clinical research data presented at TCT often direct ...
Breaking Medicine News(10 mins):Health News:Ron Johnson Named Co-Lead Counsel in Lawsuits for Men Injured by AndroGel and Testosterone 2Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 2Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 3Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 4Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 2Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 3Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 4Health News:Automotive Exhaust Systems Market Will Be $33,379.7 Million by 2019 – New Report by MarketsandMarkets 2Health News:Automotive Exhaust Systems Market Will Be $33,379.7 Million by 2019 – New Report by MarketsandMarkets 3Health News:Automotive Exhaust Systems Market Will Be $33,379.7 Million by 2019 – New Report by MarketsandMarkets 4Health News:CRF announces late-breaking trials and first report investigations for TCT 2014 2Health News:CRF announces late-breaking trials and first report investigations for TCT 2014 3Health News:CRF announces late-breaking trials and first report investigations for TCT 2014 4
... Inc. (AIS), publisher of industry-leading newsletters Health Plan,Week, ... pleased to announce,publication of "Managed Medicare and Medicaid ... and almost 30 million Medicaid recipients,enrolled in managed ... other,companies with a stake in this market place ...
... 21 Mylan Inc. (NYSE: MYL ),today ... approval,from the U.S. Food and Drug Administration (FDA) ... Extended-release Tablets USP, 2.5,mg, 5 mg and 10 ... generic version of,AstraZeneca Pharmaceutical,s Plendil(R) Extended-release tablets, which ...
... upcoming Public Meeting on April 22, 2008, the Centers ... input for the establishment of a Healthcare Common Procedure ... II of the HCPCS is a standardized coding system ... not included in the Current Procedural Terminology (CPT) coding ...
... -- China Medicine,Corporation (OTC Bulletin Board: CHME; ... and developer of ethical and over-the-counter drugs,traditional ... devices, and medical formulations in the PRC, ... the Guangzhou Technology Bureau to represent,Guangzhou city,s ...
... Research Group survey finds that approximately 45% of physicians, intend to ... ... years, WALTHAM, Mass., April ... at the American Academy of,Orthopedic Surgeons, annual meeting in San Francisco, CA, ...
... BRIGHTON, England, April 21 Futuremedia,Learning, a leading ... Bulletin Board: FMDAY), has launched Performance Zone, a ... health,and care organisation., The launch took place ... the,UK, with Futuremedia Learning staff on-site offering support ...
Cached Medicine News:Health News:New Medicare and Medicaid Data Released: Featuring Up-To-Date Enrollment Trends, State Initiatives, Regional Market Share and Prescription Drug Benefits 2Health News:Medicare to consider public opinion about medical maggots 2Health News:Medicare to consider public opinion about medical maggots 3Health News:China Medicine Corporation Selected to Represent Biotechnology Industry of Guangzhou City at 2008 Annual BIO International Convention 2Health News:China Medicine Corporation Selected to Represent Biotechnology Industry of Guangzhou City at 2008 Annual BIO International Convention 3Health News:Physicians Anticipate Changes in Their Usage of Hip Implants 2Health News:Futuremedia Learning Launches Next Generation Learning Portal for Bupa 2
... for Bi-Plane Electrophysiology imaging have become more ... time and reduce radiation exposure to both ... deciding between Single and Bi-Plane systems. ... its leadership position in price/value relationship, four ...
... is now known as Centricity® Physician Office ... - PM is designed to fit your ... easily adaptable solution as individual as your ... every specialty and size - have switched ...
... Care Electronic Medical Record portion of PrimeSuite™. ... process and electronic patient record solution within ... both mobile and secure. Using a variety ... technology with a stylus device, physicians can ...
... Practice Partner Patient Records provides a ... both office and clinical efficiency, while ... Patient Records allows practices to replace ... feature set utilized nationwide by over ...
Medicine Products: