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Pipeline Insight: Gastrointestinal Cancer Overview - Metastatic Gastrointestinal Cancers Represent a Significant Commercial Opportunity Due to a Lack of Approved Drugs
Date:11/4/2010

AB Science will need to price masitinib competitively in order to enhance its uptake 248

In order to optimize masitinib's commercial potential, AB Science should seek a partner experienced in the human oncology market 248

Satisfaction of unmet needs 248

Forecasts to 2019 249

Tertomotide (GV-1001; Pharmexa/Kael-GemVax) 250

Drug overview 250

Drug profile 250

Key historical events 251

Clinical trial data 252

A Phase III trial investigating GV-1001 followed by sequential Gemzar in advanced pancreatic cancer patients has already failed 252

Phase I/II trial data indicate an immune response is correlated with prolonged survival 253

SWOT analysis 254

Datamonitor drug assessment scorecard for GV-1001 255

Clinical and commercial attractiveness 255

Replication of Phase I/II median survival in the ongoing Phase III studies will almost surely guarantee approval 255

PrimoVax Phase III failure highlights the difficulties of sequencing chemotherapy with therapeutic cancer vaccines 256

GV-1001 may struggle to achieve optimal market penetration without a more experienced oncology player 256

A lack of precedent regarding approval of therapeutic cancer vaccines exists 257

Satisfaction of unmet needs 257

Forecasts to 2019 257

Bibliography 259

Journals 259

Websites 269

Datamonitor reports 274

Other 274

APPENDIX 275

Methodology 275

Epidemiology forecasts 275

Product forecasts 275

Datamonitor drug assessment scorecard 276

About Datamonitor 278

About Datamonitor Healthcare 278

About the Disease analysis team 278

Datamonitor consulting 279

Disclaimer

To order this report:Pharmaceutical Industry:

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