Navigation Links
Phase III data show significant reduction in blood glucose with investigational compound empagliflozin added to metformin or metformin plus sulfonylurea in adults with type 2 diabetes
Date:6/22/2013

lt;0.001) for empagliflozin 10 mg (n=225) and 25 mg (n=216), respectively, compared with placebo (n=225).2 The study also showed statistically significant placebo-adjusted reductions at 24 weeks in mean daily glucose concentration of 10.02 mg/dL and 13.06 mg/dL (p<0.001) with empagliflozin 10 mg and 25 mg., respectively. Reductions in body weight were significantly greater with the addition of empagliflozin to metformin plus sulfonylurea (change in body weight of 3.88 lbs, 10 mg; and 4.39 lbs, 25mg; p<0.001).2

Drug-related adverse events were reported by 24.1 percent, 19.8 percent and 15.1 percent of patients on empagliflozin 10 mg, empagliflozin 25 mg, and placebo, respectively. Confirmed hypoglycemia was reported in 16.1 percent of patients on empagliflozin 10 mg, 11.5 percent on empagliflozin 25 mg and 8.4 percent on placebo, none of which required assistance. Adverse events consistent with urinary tract infection were reported in 10.3 percent of patients on empagliflozin 10 mg, 8.3 percent on empagliflozin 25 mg and 8.0 percent on placebo. Adverse events consistent with genital infection were reported in 2.7 percent of patients on empagliflozin 10 mg, 2.3 percent on empagliflozin 25 mg and 0.9 percent on placebo.

About the Empagliflozin Phase III Clinical Trial Program
Empagliflozin is being investigated in adults with T2D in a phase III clinical trial program that has enrolled more than 14,500 patients. This program includes more than 10 multinational clinical trials, including a large cardiovascular outcomes trial.

About Diabetes
Approximately 25.8 million Americans3 and an estimated 371 million people worldwide4 have type 1 or type 2 diabetes. T2D is the most common type, accounting for an estimated 90 to 95 percent of all diabetes cases.3 Diabetes is a chronic condition that occurs when the body does not properly produce or use the hormone insulin.5 Diab
'/>"/>

SOURCE Eli Lilly and Company; Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
2. Anthera Announces the Completion of Patient Dosing in Phase 2b PEARL-SC Study
3. Omthera Pharmaceuticals Announces Positive Top-Line Results from Phase 3 EVOLVE Study
4. Retrospective Study Suggests that Stereotactic Ablative Radiotherapy (SABR) Can be a Viable Option for Treating Early-Stage Lung Cancer in Operable as well as Inoperable Patients; Phase III Randomized Trial Now Under Way
5. Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease
6. Lexicon Receives Funding for Phase 2 Clinical Trial of LX4211 in Type 1 Diabetes
7. Isis Initiates Phase 2 Study of ISIS-APOCIIIRx in Patients with Hypertriglyceridemia
8. Alder BioPharmaceuticals Inc. Initiates Phase 1 Clinical Study of Antibody Therapeutic Candidate for Treatment of Migraine, ALD403
9. Results Reported for Phase Ib Open-Label Clinical Trial for the Treatment of Depression Using External Trigeminal Nerve Stimulation (eTNS™) - The USB Port to the Brain™
10. Pearl Therapeutics Phase 2b Twice-Daily Dosing Data Suggest Morning and Evening Benefit of PT003 in Patients with COPD
11. Adamas Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA for Arimenda™
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)...  Northwest Biotherapeutics (NASDAQ: NWBO ) (NW ... for solid tumor cancers, announced today that the $17.5 ... 2014, has closed.  The three-year notes have a 5% ... of common stock.  The investors also have an option, ... additional 30% of these notes on the same terms. ...
(Date:8/19/2014)... Aug. 19, 2014  Tokyo-based Atonarp Inc. announced ... round led by Walden Riverwood Ventures with participation ... of Atonarp,s Smart Spectrometer technology platform, which will ... has targeted the oil & gas and healthcare ... are excited to partner with Atonarp in pursuing ...
(Date:8/19/2014)... 19, 2014 Avizia, Inc., a leading provider ... closed an equity financing round led by NextGen Angels ... new funding will be used to continue to fuel ... Avizia welcomes Edward Kennedy , CEO and president ... joins Leonard Kurtzman , CFO of newBrandAnalytics, who ...
Breaking Medicine Technology:NW BIO COMPLETES THE CLOSING OF ITS $17.5 MILLION CONVERTIBLE NOTE OFFERING 2NW BIO COMPLETES THE CLOSING OF ITS $17.5 MILLION CONVERTIBLE NOTE OFFERING 3Atonarp Inc. Raises $8M Series A Round Led by Walden Riverwood Ventures 2Avizia Closes Funding Round 2
(Date:8/20/2014)... “Have you recently been involved in an auto accident?” asks ... the greater Seattle area. “Are you still feeling the physical ... . , In a recently released article, Dax Jones asks ... use to see if they may qualify for a personal ... will allow an individual to receive medical treatment for their ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 The ... (Short Acting, Intermediate Acting, Premixed), Modern Human Insulin ... Apidra, Levemir, NovoRapid, Novomix, Tresiba, Others) - Forecast ... major drivers,restraints, challenges, opportunities, current market trends,and strategies ... the estimates and forecasts of the revenue and ...
(Date:8/20/2014)... 20, 2014 Mixberry Media announced today ... websites and create a new source of revenue. , ... by listening to a narration of their favorite news ... and languages. Users can now multitask: read/write email, ... while consuming content. , Mixberry Media’s service ...
(Date:8/20/2014)... Astoria, New York (PRWEB) August 20, 2014 ... to the Global Bureau of Disease, low back pain is ... of the most common reasons for missed work. Americans spend ... of this pain. , Most cases of back pain are ... a mechanical (non-organic) origin. , For example, Pete, a busy ...
(Date:8/19/2014)... 20, 2014 Midtown Dentistry in Houston, Texas, ... office. All patients with cavities, or with old fillings ... fillings that can safely repair and restore teeth. , From ... latest materials, all of which are completely amalgam free. Even ... use by the FDA for adults and children over the ...
Breaking Medicine News(10 mins):Health News:Five Questions to Determine Who Qualifies for a Personal Injury Claim Recently Released by The Jones Firm in Recent Article 2Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Mixberry Media, First To Offer Article Voice Narration with Integrated Audio Advertising 2Health News:Physical Therapists Learn to Relieve Low Back Pain 2Health News:Midtown Dentistry Announces It Is Now an Amalgam-Free Office 2
... , , WASHINGTON , Jan. 13 ... and Bruce A. Mrusek , a resident of Maineville, Ohio , ... Judge Michael R. Barrett in Cincinnati , the Justice Department ... both dentists, wer e i n d ...
... say , WEDNESDAY, Jan. 13 (HealthDay News) -- ... tendon doesn,t appear to be effective, a new study ... plasma (PRP) injections are no better than placebo in ... active. , The study included 54 patients, aged 18 ...
... And rates among boys aged 6-19 still climbing, government study ... news in the war on weight: Obesity in the United ... studies show. , But the rates of obesity remain high, ... category. And, rates of obesity among already heavy 6- to ...
... researchers have found that six essential oils from thyme, ... COX-2 enzyme, in a manner similar to resveratrol, the ... They also identified that the chemical carvacrol was primarily ... appearing in the January issue of Journal of ...
... ... to provide fully integrated topical clinical phase 1 study services for trials in healthy ... , ... January 13, 2010 -- Synomics Pharma and BioScience Laboratories, Inc. announced a formal partnership ...
... January 21st ... Understand the Latest Developments in VoIP Fax Capabilities, , ... Tigard, Oregon (Vocus) January 13, 2010 -- FaxBack , the ... the Miami Beach Convention Center. , , , , ,At the show, FaxBack (booth ...
Cached Medicine News:Health News:Two Cincinnati Dentists Plead Guilty to Conspiracy, Tax Evasion on Eve of Trial 2Health News: U.S. Obesity Rates Leveling Off, But Still High 2Health News: U.S. Obesity Rates Leveling Off, But Still High 3Health News:Synomics Pharma and Bioscience Laboratories Announce Partnership to Provide Topical Clinical Phase 1 Study Services 2Health News:Synomics Pharma and Bioscience Laboratories Announce Partnership to Provide Topical Clinical Phase 1 Study Services 3Health News:FaxBack Participates in VoIP Fax Discussion at ITEXPO 2Health News:FaxBack Participates in VoIP Fax Discussion at ITEXPO 3
Inquire...
... brings you into the new age of ... offer your patients immediate, long-term results for ... This injectable filler offers superior versatility for ... reconstructive treatments. Long-lasting, Radiesse saves time and ...
... HEMOCHRON Response is a whole ... to be used at the ... easy-to-read screen and data management ... ID options. QC and operator ...
... Revitol Cellulite Cream is a revolutionary ... eliminating inches. Revitol Cellulite Removal Cream permits ... problem areas. With Revitol you can rid ... Just apply the Cellulite Cream to your ...
Medicine Products: