Navigation Links
Phase I and Phase I/II DCVax(R)-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients
Date:2/20/2008

Year-end 2007 long-term follow-up data continues to be positive

BETHESDA, Md., Feb. 20 /PRNewswire-FirstCall/ -- Northwest Biotherapeutics, Inc. (OTC Bulletin Board: NWBO; AIM: NWBT and NWBS) ("NWBT" or the "Company") today announced the most recent long-term follow-up data, as of year-end 2007, on disease progression and overall survival in patients taking part in its Phase I and Phase I/II clinical trials for newly diagnosed patients with Glioblastoma multiforme ("GBM"), the most aggressive form of brain cancer. The additional data covers the period from April 2007 through year-end 2007. During this time, none of the patients experienced disease progression (recurrence) and only one patient died (at 36.4 months). Thus, the data show that in the 19 clinical trial patients receiving DCVax(R)-Brain in addition to Standard of Care, both the median overall survival and the median time to disease progression (recurrence) are more than twice as long as in patients receiving the Standard of Care for GBM. Dr. Linda Liau, Associate Professor of Neurosurgery and Director of the Malignant Brain Tumor Program at the UCLA School of Medicine ("UCLA"), served as the Principal Investigator for the trial.

Since 2005, the Standard of Care for patients with GBM is surgery followed by a combination of radiation and daily Temodar(R) chemotherapy, and then 6 monthly cycles of Temodar chemotherapy. The studies defining this Standard of Care achieved a median time to progression of 6.9 months and a median overall survival of 14.6 months (Stupp, et. al., N Engl J Med, 352:987, 2005). Further data from UCLA have demonstrated a somewhat longer median time to progression of 8.1 months and median overall survival of 17.0 months in patients with GBM who received Standard of Care.

The year-end 2007 data obtained by the Company concerning the 19 patients from the two trials at UCLA with newly diagnosed GBM continue to be positive, with no patients progressing and onl
'/>"/>

SOURCE Northwest Biotherapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
3. Progen Engages Leading CRO to Assist with Phase 3 Trial of PI-88
4. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
5. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
6. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
7. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. TaiGen Biotechnology Successfully Completes Patient Recruitment for Phase II Trial of Nemonoxacin for Treatment of Adult Community Acquired Pneumonia (CAP)
10. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
11. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... , July 11, 2014 ... visitors to Safety & Health Expo 2014 ... the move to London ... management attending exhibition.     ... http://photos.prnewswire.com/prnh/20140711/696892-a )      ...
(Date:7/10/2014)... Virginia , 11. Juli 2014 ... von Kameras für die molekulare Bildgebung, ... hat heute die CE-Zulassung für sein ... CE-Zeichen kann Dilon das Produkt jetzt ... auf den Großteil der europäischen Länder ...
(Date:7/10/2014)... , July 10, 2014 Integrated Silicon Solution, ... advanced memory and analog IC solutions, today announced that ... July 24, 2014, at 7:00 a.m. Pacific Time (10:00 ... for the fiscal 2014 third quarter ended June 30, ... telephone, dial 1-888-556-4997 before 6:50 a.m. Pacific time on ...
Breaking Medicine Technology:UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2
... 30 A 17-year-old female with a complex ... in India to be treated using the fast Novalis Tx(TM) ... VAR ) and BrainLAB. Doctors at Kokilaben Dhirubhai Ambani Hospital ... single session that took just a few minutes to complete. ...
... Life Spine announced today that the U.S. Food ... to the SENTINEL Occipito-Cervico-Thoracic (OCT) System. , The ... from the occiput to thoracic spine, and features streamlined ... are available in multiple diameters and lengths, and offer ...
Cached Medicine Technology:Pioneering Brain Malformation Treatment Performed Using Novalis Tx(TM) Radiosurgery Technology in India 2Pioneering Brain Malformation Treatment Performed Using Novalis Tx(TM) Radiosurgery Technology in India 3Pioneering Brain Malformation Treatment Performed Using Novalis Tx(TM) Radiosurgery Technology in India 4
(Date:7/14/2014)... Germany (PRWEB) July 14, 2014 EurekaMag.com ... Hepatitis C which is a contagious liver disease ... a few weeks to a serious, lifelong illness that ... the United States have chronic Hepatitis C virus infection ... While the site's research category covers all studies ...
(Date:7/14/2014)... 14, 2014 According to ... review recently updated by Vkool.com, this is ... wide range of simple and easy tips ... including:,     Increasing omega-3 fatty ... products ,     Increasing fiber , ...
(Date:7/14/2014)... 14, 2014 Carepoint has been ... caregiving by combining an intuitive interface for recording, ... robust service tracking and reporting features. , Hall ... has teamed up with Rebecca de Witte to ... healthcare organizations. , Carepoint provides seamless, ...
(Date:7/14/2014)... 14, 2014 Vaginal Mesh lawsuit ... seven different pelvic mesh manufacturers in the U.S. District ... Schulte LLC. The federal complaints are pending against pelvic ... American Medical Systems (MDL No. 2325), and C.R. Bard, ... are 58,262 Vaginal Mesh lawsuit claims pending, according to ...
(Date:7/14/2014)... DC (PRWEB) July 14, 2014 ... exchanges, carriers emphasized lower-cost narrow-network products, accountable care ... generally chose coverage based on price, rather than ... enrollees from seeking care from out-of-network providers. ... ACOs, Narrow Networks and Exchange Products,” the ...
Breaking Medicine News(10 mins):Health News:EurekaMag.com Publishes 64,900 New Studies on Hepatitis C 2Health News:Endometriosis Bible and Violet Protocol Book Review Exposes Zoe Brown's Endometriosis Treatment Guide – Vkool.com 2Health News:Endometriosis Bible and Violet Protocol Book Review Exposes Zoe Brown's Endometriosis Treatment Guide – Vkool.com 3Health News:Home Health Care Professional and Marketing Firm Team Up to Create New Homecare Communication App 2Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 2Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 3Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 4Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 5Health News:Milliman, FAIR Health Executives to Discuss Data-Based Rate Setting for Out-of-Network Providers in Atlantic Information Services Webinar 2
... appears to reduce the number of hot flashes and other ... of the drug Estrasorb. If approved by regulatory authorities, it ... ,The drug's developer Novavax Inc. said that in ... the total number of hot flashes during the course of ...
... Down syndrome live twice as long today as they did in ... of developing many forms of cancer. ,The study by Quanhe ... data collected from death certificates between 1980 and 1995 in the ... the 10,800 reported to have Down syndrome increased from 25 years ...
... implanting cells into the brains of Parkinson's disease patients ... Watts, professor of //neurology at Emory University School of ... function - movement of their arms and legs - ... implanted retinal pigment epithelial cells, which are grown by ...
... survey shows that Americans are opting for dental implants to ... injury or decay, //the traditional solution to the problem is ... bridge that is inserted into the mouth. But implants teeth ... growing in popularity according to the American Dental Association's latest ...
... of the eye need not have to remove their dieased ... The results of the Collaborative ocular Melanoma Study(COMS), ... that survival rates were the same regardless of whether the ... therapy. , Davidorf, Professor of ...
... to avoid swordfish, shark, king mackerel, tilefish, tuna steaks, ... white croaker, and largemouth bass. The Environmental Working Group ... only small amounts of fresh-caught fish once a week. ... its warning to pregnant women about the dangers of ...
Cached Medicine News:Health News:Down syndrome life anticipation doubles 2
High resolution, multi-frequency, HST version of the UST-987-7.5. Provides even greater image detail, better resolution, and penetration....
... Penetration Steered Linear Peripheral Vascular transducer, with ... MHz. It is our newest vascular ... 4 different settings to optimize imaging of ... color and Doppler sensitivity of this transducer ...
... Super High Density, multi-frequency, linear ... "twist on the UST-5536, this ... it sweeps horizontally as well ... axis so that target lesions ...
... The UST-MC11-8731 is a perfect alternative ... are used to seeing more of a ... of the transducer in the hand., This ... shaped convex intraoperative transducer. The UST-MC11-8731 nestles ...
Medicine Products: