Navigation Links
Phase 3 Trial of Nexavar in Chemotherapy-Naive Patients with Advanced Melanoma Does Not Meet Primary Endpoint
Date:4/26/2009

overnment agencies and individual investigators as a single agent or combination treatment in a wide range of cancers, including lung cancer, breast cancer and as an adjuvant therapy for kidney and liver cancer.

Important Safety Considerations For Patients Taking Nexavar

Based on the currently approved U.S. package insert for the treatment of patients with unresectable hepatocellular carcinoma and advanced kidney cancer, hypertension may occur early in the course of therapy and blood pressure should be monitored weekly during the first six weeks of therapy and treated as needed. In HCC patients, bleeding with a fatal outcome from any site was reported in 2.4% for Nexavar and 4% in placebo. The incidence of treatment-emergent cardiac ischemia/infarction was 2.7% for Nexavar vs. 1.3% for placebo. In RCC patients, incidence of bleeding regardless of causality was 15% for Nexavar vs. 8% for placebo and the incidence of treatment-emergent cardiac ischemia/infarction was 2.9% for Nexavar vs. 0.4% for placebo. Most common adverse events greater than or equal to 20% related to Nexavar for both HCC and RCC were fatigue, weight loss, rash/desquamation, hand-foot skin reaction, alopecia, diarrhea, nausea, and abdominal pain. Grade 3/4 adverse events in HCC and RCC patients, respectively, were 45% for Nexavar vs. 32% for placebo and 38% for Nexavar and 28% for placebo. Women of child-bearing potential should be advised to avoid becoming pregnant and advised against breast-feeding. In cases of any severe or persistent side effects, temporary treatment interruption, dose modification or permanent discontinuation should be considered.

For information about Nexavar including U.S. Nexavar prescribing information, visit www.nexavar.com or call 1.866.NEXAVAR (1.866.639.2827).

About Bayer HealthCare Pharmaceuticals Inc.

Bayer HealthCare Pharmaceut
'/>"/>

SOURCE Onyx Pharmaceuticals, Inc.; Bayer HealthCare Pharmaceuticals
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Human Genome Sciences Reports Positive Late-Breaker Results at EASL from ACHIEVE Phase 3 Trials of Albuferon(R) in Patients with Chronic Hepatitis C
2. Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C
3. Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes
4. Ridge Diagnostics, Inc. Awarded Phase 2 National Science Foundation Grant
5. ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients
6. Addrenex Pharmaceuticals Reports Positive Results in Second Phase 3 Study of ADHD Medication
7. Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients
8. Phase 1 Trial of Whole-Parasite Malaria Vaccine to Begin
9. BioMarin Initiates Phase 1/2 Clinical Trial for GALNS for Morquio A Syndrome
10. ImQuest BioSciences Receives Phase I SBIR Grant to Develop a Novel Hepatitis C Virus Therapeutic Agent
11. Dendreon Initiates Phase 1 Clinical Trial of Small Molecule Targeting TRPM8 in Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... Nov. 21, 2014  The University of Maryland,s A. ... ceremonial groundbreaking of the new A. James Clark Hall ... building will cultivate transformative new engineering and biomedical technologies ... place at 10:00 a.m. on November 21 at the ... Parking Lot, adjacent to the Jeong H. Kim Engineering ...
(Date:11/21/2014)... DIEGO , Nov. 21, 2014  Tandem ... TNDM ), a medical device company and manufacturer ... announced a partnership with Tidepool, a non-profit dedicated ... open source software platform that increases diabetes data ... Tidepool Platform, which is currently under development, to ...
(Date:11/21/2014)... , Nov. 21, 2014   Rock Creek Pharmaceuticals, ... the Company is scheduled to present at the Biotech ... CA on January 12-14, 2015. ... CEO of Rock Creek Pharmaceuticals, will present preclinical and ... agonist which exhibits anti-inflammatory pharmacological characteristics. Dr. Mullan will ...
Breaking Medicine Technology:University of Maryland Breaks Ground for A. James Clark Hall 2University of Maryland Breaks Ground for A. James Clark Hall 3University of Maryland Breaks Ground for A. James Clark Hall 4Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 2Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 3Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 2Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 3Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 4
... Dear President-Elect Obama:, , ... billions of dollars,earmarked for stem cell research. As spokesman ... of the Repair Stem Cell research and,treatment industry worldwide, I ... our industry and the medical and scientific professionals,hospitals, treatment centers ...
... Tenn., Nov. 24 A new cancer treatment ... weeks,of treatment, a patient,s large, stage 4 tumor ... weeks of treatment, it no longer could be ... six to nine months,after diagnosis. NeoPlas Innovation,s combination ...
Cached Medicine Technology:Open Letter to President-Elect Barack Obama From Don Margolis, Chairman and Founder of The Repair Stem Cell Institute 2New Cancer Treatment Shrinks Pancreatic Tumor 2
(Date:11/23/2014)... Falls Church, VA (PRWEB) November 23, 2014 ... and TV Have in Common, **FDAnews On-Demand Webinar**, Dec. ... http://www.fdanews.com/TheFDAisWatchingOnDemand , The FDA’s focus on promotional ... ads. , Now they're looking at websites, ... , Mark the calendar for Thursday, Dec. 11, for ...
(Date:11/23/2014)... Columbus, OH (PRWEB) November 23, 2014 ... claims on behalf of Ohio and West Virginia residents ... and other health disorders due to drinking C8 ... Plant In Parkersburg, West Virginia. According to the C8 ... because they either worked or lived in at least ...
(Date:11/23/2014)... City, Utah (PRWEB) November 23, 2014 ... health insurance reimbursement for small businesses, announced their ... book, The End of Employer-Provided Health Insurance. ... insurance is the greatest financial risk facing most ... facing U.S. employers, small and large, when it ...
(Date:11/22/2014)... A new AlignLife Chiropractic & Natural ... downtown Greenville area. Dr. Chelsea Sineath, owner and chiropractor ... open her own clinic after working in another AlignLife ... , AlignLife believes that the body can heal ... on chiropractic care and rehabilitation to allow the spine ...
(Date:11/22/2014)... PrettyTailor , an outstanding dress company, has recently ... can buy new dresses at its online shop now. ... , As a matter of fact, PrettyTailor specializes in ... four types of wedding outfits, including bridesmaid dresses, mother ... also provides a variety of occasion dresses, such as ...
Breaking Medicine News(10 mins):Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 2Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 3Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 5Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 3Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 4Health News:Zane Benefits, Inc. Announces New Webinar on The End of Employer-Provided Health Insurance Now Available On-Demand! 2Health News:AlignLife of Downtown Greenville is Now Open and Accepting New Patients 2Health News:Customers Are Welcome to Shop at PrettyTailor.com 2
... brain scans to try and study the biology of dread. ... brain pays to the expected pain // determines and whether ... that simple diversions could alleviate the misery. ,The ... new field called neuroeconomics that uses brain imaging to try ...
... Baeg Moon-hong. He is a senior researcher at the Korea ... was show cased in an exhibition at the Seoul Education ... meters tall. The special features are that it can understand ... expressions. , The first android was made by ...
... the shaking leg syndrome is a common type of disorder in ... For the first time Europe has approved the drug to be ... aches and pains. Statistics show that about 10% of the people ... by the European Medicines Agency. As of now it is used ...
... Health conscious people here lawyers in California have sued PepsiCo ... benzene//., ,The drink in question is Pepsi Twist drink, ... three' soft drinks firms has been drawn into a legal ... the lawsuit, "Pepsi Twist has been falsely promoted as a ...
... the Supreme Court Friday reversed an earlier order directing ... all-India basis// for scheduled castes and scheduled tribes candidates ... ,A bench of judges K.G. Balakrishnan, A.R. Lakshmanan ... General Gopal Subramaniam that enforcing the 10 percent quota ...
... kid of Orissa, declared that his health is normal. // ... up after he ran an astounding 65km earlier this week. ... at Bhubaneswar for a medical check up on the orders ... coach Biranchi Das was exploiting the boy for his personal ...
Cached Medicine News:Health News:Supreme Court Quashed Reservation Quotas For PG Medical Courses 2Health News:Marathon Kid Budhia’s Health Not Compromise 2
... Exact uses rapid technology to ... A Streptococcal antigen from throat ... A Exact uses a patented, ... sensitive and specific results for ...
One inch disposable patch electrode uses a specially formulated adhesive solid gel. Reusable lead wire with snap connector provides economic benefits. Ideal for sleep studies where leg movement or EK...
10-mm (0.4-in) diameter cups have multi-color lead wires and 2-mm (0.08-in) holes for easy paste/collodion application. Available in a variety of lengths to suit many different needs....
... elastic fabric, these head cap systems are ... begin testing. Each Electro-Cap System features pure ... 10-20 System. When you place your order, ... with your head cap system and whether ...
Medicine Products: