Navigation Links
Phase 3 Open-Label Study Comparing Tapentadol Extended Release Tablets to Oxycodone Controlled Release Tablets Published by Pain Practice
Date:7/19/2010

ey.com/cgi-bin/fulltext/123567330/PDFSTART.

About tapentadol

Tapentadol is a centrally acting oral analgesic that binds to mu-opioid receptors and inhibits norepinephrine re-uptake. Although the exact mechanism of action is not known, these two mechanisms, which affect established pain pathways, are thought to be responsible for pain relief with tapentadol. The tapentadol molecule is classified as Schedule II of the Controlled Substances Act.

NUCYNTA® (tapentadol immediate release) was approved by the FDA on November 20, 2008, and is available by prescription only for the relief of moderate to severe acute pain in patients 18 years of age or older. On December 1, 2009, J&JPRD submitted its New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for tapentadol extended release (ER) tablets for the management of moderate to severe chronic pain in patients 18 years of age or older. The tapentadol ER tablet formulation is designed to provide a high degree of mechanical resistance, such as to crushing or chewing. The NDA filing is part of the ongoing commitment of J&JPRD and PriCara® to bring new and innovative products to patients and physicians for the treatment and management of pain.

IMPORTANT SAFETY INFORMATION FOR NUCYNTA® (tapentadol)

Like other drugs with mu-opioid agonist activity, NUCYNTA® is contraindicated in patients with significant respiratory depression, acute or severe bronchial asthma or hypercapnia in unmonitored settings or in the absence of resuscitative equipment. NUCYNTA® is contraindicated in patients who have or are suspected to have paralytic ileus. NUCYNTA® is also contraindicated in patients currently using or within 14 days
'/>"/>

SOURCE PriCara
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
3. Progen Engages Leading CRO to Assist with Phase 3 Trial of PI-88
4. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
5. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
6. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
7. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. TaiGen Biotechnology Successfully Completes Patient Recruitment for Phase II Trial of Nemonoxacin for Treatment of Adult Community Acquired Pneumonia (CAP)
10. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
11. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ... Equipment, Inc. for the third straight year, No. ... 500|5000, an exclusive ranking of the nation,s fastest-growing ... look at the most important segment of the ... Timberland, Dell, Domino,s Pizza, LinkedIn, Zillow, and many ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ScriptPro ... Alliance (HITRUST) under its Common Security Framework (CSF). ... Security and Privacy Manager, "We appreciate this rigorous, ... of commitment that this certification signifies. Our business ... ABOUT THE CSF CERTIFICATION PROCESS: ScriptPro,s internal ...
(Date:8/21/2014)... , Aug. 21, 2014  Zacks.com announces the list of ... Equity Research analysts discuss the latest news and events impacting ... blog include the Hewlett-Packard (NYSE: HPQ - Free Report ), ... Inc. (NYSE: SB - Free Report ), GlaxoSmithKline plc ... N.V. (NYSE: FI - Free Report ). ...
Breaking Medicine Technology:Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3ScriptPro Achieves HITRUST Certification 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 3The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 4The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 5The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 6The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 7The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 8The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 9The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 10The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 11
... Feb. 15, 2012  LodgeNet Interactive Corporation (Nasdaq: ... connectivity services to hospitality and healthcare businesses and the ... its Fourth Quarter and full year 2011 results after ... (Logo:  http://photos.prnewswire.com/prnh/20080115/AQTU120LOGO ) The Company ...
... /PRNewswire-iReach/ -- The more companies learn about ... special injection-molding technology to add value to their product lines. ... total production costs—that,s pretty rare these days. So, ... process, a thin layer of TPE (thermoplastic elastomer) is overshot ...
Cached Medicine Technology:LodgeNet Interactive to Report Fourth Quarter and Full Year 2011 Results on February 22nd 2Add Value Through Overmolding 2Add Value Through Overmolding 3
(Date:8/22/2014)... 22, 2014 Pirate Jonny's ... products in providing new recipe cards, fun t-shirts, and ... , Hailing from Clearwater, Florida, Pirate Jonny, aka, Jonathan ... card with two to three recipes featuring different flavors ... on the website. The recipe cards will ...
(Date:8/22/2014)... August 22, 2014 Until now, those with ... crutches or walkers to keep mobile. Thanks to an inventor ... much more effective. , He developed a prototype for the ... injured leg or foot but provide comfort and reduce pain ... different heights, it is also convenient and easy to install ...
(Date:8/22/2014)... 2014 The report "Higher Education ... & Compliance, Campus Technology, Student & Curriculum, Performance ... defines and segments the global Higher Ed market ... forecasting of market sizes. The report also identifies ... opportunities impacting it along with the adoption trends. ...
(Date:8/22/2014)... Institutet in Sweden provides insight on how the brain ... from different sources and sides of the body, in ... which are presented in the journal Neuron , ... integrating various types of sensory information, with specialised functional ... is the main input structure in the basal ganglia, ...
(Date:8/22/2014)... dramatic images of nurses at New York University,s Langone ... carrying many including the youngest and most vulnerable down ... the storm surge generated by Hurricane Sandy. , ... York University Colleges of Nursing (NYUCN) and of Dentistry ... examines the impact on NYULMC nurses, post-Sandy deployment ...
Breaking Medicine News(10 mins):Health News:Pirate Jonny's Caribbean BBQ Rubs, Seasonings & Sauces Get New Look by Hoisting New Recipe Card Creations and New Clothing Apparel for its Logos 2Health News:Assistive Device for Walking Invented by InventHelp Client (VBL-501) 2Health News:Higher Education Market Worth $65.83 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Higher Education Market Worth $65.83 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Higher Education Market Worth $65.83 Billion by 2019 - New Report by MarketsandMarkets 4Health News:The striatum acts as hub for multisensory integration 2Health News:Study identifies challenges faced by NYU nurses after Hurricane Sandy 2Health News:Study identifies challenges faced by NYU nurses after Hurricane Sandy 3
... Calif., Jan. 6 Onyx Pharmaceuticals, Inc. (Nasdaq: ... to license rights to SB1518, an orally available, potent, and ... a JAK2 inhibitor, from S*BIO Pte Ltd based in Singapore. ... option rights to exclusively develop and commercialize SB1518 (designated by ...
... and SAN DIEGO, Jan. 6 BioMarin,Pharmaceutical Inc. (Nasdaq: ... LJPC ) announced today that they have ... Jolla,s investigational drug for,lupus nephritis, in the United States, ... Asia Pacific region. Following a successful Phase 3,trial, the ...
... wrist at 3T is an effective way to detect wrist ligament ... a study performed at Neuroskeletal Imaging in Merritt Island, Florida. ... and arthroscopy; 51 tears were found on arthroscopy. 41 of the ... 3T MRI is good. We are able to see the small ...
... shoulder allows physicians to better identify tears and provides ... not surgery is needed, according to a study performed ... The study included 150 patients who underwent both 3T ... did the study to see if MR, which is ...
... French . , Recent animal studies ... once used to treat diarrhea and other gastrointestinal disorders ... Huntington,s diseases. Scientists, however, had a variety of theories ... have such similar effects on three unrelated neurodegenerative disorders. ...
... (Nasdaq: WCRX ) today announced that it ... based in Korea, to develop and market their orally-administered ... the treatment of erectile dysfunction (ED) in the United ... of the product in the United States.Under the terms ...
Cached Medicine News:Health News:Onyx Pharmaceuticals Acquires Option to License Novel Highly Specific JAK2 Inhibitors From S*BIO 2Health News:Onyx Pharmaceuticals Acquires Option to License Novel Highly Specific JAK2 Inhibitors From S*BIO 3Health News:Onyx Pharmaceuticals Acquires Option to License Novel Highly Specific JAK2 Inhibitors From S*BIO 4Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 2Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 3Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 4Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 5Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 6Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 7Health News:BioMarin and La Jolla Pharmaceutical Sign Worldwide (Excluding Asia Pacific) Development and Commercialization Agreement for Riquent 8Health News:MR arthrography is more accurate than MR in diagnosing shoulder tears 2Health News:Old gastrointestinal drug slows aging, McGill researchers say 2Health News:Warner Chilcott and Dong-A Sign U.S. License Agreement For Erectile Dysfunction Treatment 2Health News:Warner Chilcott and Dong-A Sign U.S. License Agreement For Erectile Dysfunction Treatment 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: