Navigation Links
Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN)
Date:5/17/2012

or in the absence of resuscitative equipment.
  • NUCYNTA® ER is contraindicated in any patient who has or is suspected of having a paralytic ileus.
  • NUCYNTA® ER is contraindicated in patients who are receiving monoamine oxidase inhibitors (MAOIs) or who have taken them within the last 14 days due to potential additive effects on norepinephrine levels, which may result in adverse cardiovascular events.
  • NUCYNTA® ER is contraindicated in patients with a known hypersensitivity to the active substance, tapentadol, or any component of the product. Angioedema has been reported in association with use of tapentadol.
  • WARNINGS & PRECAUTIONS

    • NUCYNTA® ER tablets are to be swallowed whole and are not to be split, broken, chewed, dissolved, or crushed. Taking split, broken, chewed, crushed, or dissolved NUCYNTA® ER tablets leads to the rapid release and absorption of a potentially fatal dose of tapentadol. 
    • NUCYNTA® ER tablets must be kept in a secure place out of the reach of children. Accidental consumption of NUCYNTA® ER, especially in children, can result in a fatal overdose of tapentadol.
    • Respiratory depression is the primary risk of mu-opioid agonists. Respiratory depression occurs more frequently in elderly or debilitated patients and in those suffering from conditions accompanied by hypoxia, hypercapnia, or upper airway obstruction, in whom even moderate therapeutic doses may significantly decrease pulmonary ventilation.
    • Use NUCYNTA® ER with caution in patients with conditions accompanied by hypoxia, hypercapnia, or decreased respiratory reserve, such as: asthma, chronic obstructive pulmonary disease or cor pulmonale, severe obesity, sleep apnea syndrome, myxedema, kyphoscoliosis, central nervous system (CNS) dep
      '/>"/>

    SOURCE Janssen Pharmaceuticals, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7 8 9 10 11 12

    Related medicine technology :

    1. NVA237 Phase III GLOW2 Data at American Thoracic Society (ATS) International Conference and Phase II Clinical Trial Update
    2. Boehringer Ingelheim to present pivotal Phase III results for afatinib in first-line treatment of EGFR mutation-positive NSCLC at ASCO 2012
    3. Inovio Pharmaceuticals Universal Avian Flu Vaccine Generates Protective Antibody Responses Against Six H5N1 Viruses in Phase I Trial
    4. Novelos Therapeutics Successfully Completes First Cohort In Phase 1b Solid Tumor Trial With I-131-CLR1404 (HOT) Cancer-Targeted Molecular Radiotherapeutic
    5. Adamas Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA for Arimenda™
    6. Pearl Therapeutics Phase 2b Twice-Daily Dosing Data Suggest Morning and Evening Benefit of PT003 in Patients with COPD
    7. Results Reported for Phase Ib Open-Label Clinical Trial for the Treatment of Depression Using External Trigeminal Nerve Stimulation (eTNS™) - The USB Port to the Brain™
    8. Alder BioPharmaceuticals Inc. Initiates Phase 1 Clinical Study of Antibody Therapeutic Candidate for Treatment of Migraine, ALD403
    9. Isis Initiates Phase 2 Study of ISIS-APOCIIIRx in Patients with Hypertriglyceridemia
    10. Lexicon Receives Funding for Phase 2 Clinical Trial of LX4211 in Type 1 Diabetes
    11. Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:8/21/2014)... 21, 2014 /PRNewswire-iReach/ -- Inc. magazine ... the third straight year, No. 349 in Health ... ranking of the nation,s fastest-growing private companies. The ... most important segment of the economy—America,s independent entrepreneurs. ... Pizza, LinkedIn, Zillow, and many other well-known names ...
    (Date:8/21/2014)... Aug. 21, 2014 /PRNewswire-iReach/ -- ScriptPro has been ... under its Common Security Framework (CSF). According to ... Privacy Manager, "We appreciate this rigorous, top-to-bottom audit. ... that this certification signifies. Our business partners need ... THE CSF CERTIFICATION PROCESS: ScriptPro,s internal security processes ...
    (Date:8/21/2014)... 2014  Zacks.com announces the list of stocks featured in ... discuss the latest news and events impacting stocks and the ... (NYSE: HPQ - Free Report ), IBM (NYSE: ... SB - Free Report ), GlaxoSmithKline plc (NYSE: GSK ... FI - Free Report ). Today, Zacks is ...
    Breaking Medicine Technology:Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3ScriptPro Achieves HITRUST Certification 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 3The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 4The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 5The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 6The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 7The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 8The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 9The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 10The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 11
    ... HARLEYSVILLE, Pa. and LUDWIGSHAFEN, Germany, Oct. 20, 2011 ... the development of future film coating systems using Kollicoat® ... Colorcon has developed a pre-formulated additive ... enables efficient preparation and application of this polymer in ...
    ... Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) today ... management to discuss third quarter 2011 financial results, as well ... 2011, at 5:00 p.m. Eastern Time (2:00 p.m. Pacific Time). ... will be released earlier that day. Interested parties ...
    Cached Medicine Technology:Colorcon and BASF Announce Collaboration to Develop Film Coating Applications Using Kollicoat® Smartseal 30 D 2
    (Date:8/21/2014)... 2014Popular fiction that normalizes and glamorizes violence against women, ... associated with a greater risk of potentially harmful health ... study are presented in the article " Fiction or ... Adolescent and Young Adult Females ," published in ... Mary Ann Liebert, Inc., publishers . The article ...
    (Date:8/21/2014)... Individuals with schizophrenia often have trouble engaging in ... new study from San Francisco State University suggests the ... of effort required to complete tasks. , The research, ... Journal of Abnormal Psychology , can assist health ... and help those patients function normally by breaking up ...
    (Date:8/21/2014)... Entries are now open for the ... national awards program totally dedicated to recognizing excellence in ... leadership. The entry deadline is Oct. 17. , The ... the first and only national magazine entirely devoted to ... “We launched the HREI Insights Awards program last year ...
    (Date:8/21/2014)... 2014 Recently it came to the ... located in Massachusetts has made public claims on August ... patient verification system in the Massachusetts cannabis industry. While ... our growing and compassionate industry we must set the ... are inaccurate. , MarijuanaDoctors.com has actually been providing ...
    (Date:8/21/2014)... HealthDay Reporter THURSDAY, Aug. 21, 2014 ... respiratory syncytial virus (RSV), a leading cause of pneumonia in ... in being able to treat human RSV infections -- the ... to influenza virus," said study author Dr. John DeVincenzo, a ... Medicine in Memphis. "There is no current treatment ...
    Breaking Medicine News(10 mins):Health News:Women's health and Fifty Shades: Increased risks for young adult readers? 2Health News:Difficulty assessing effort drives motivation deficits in schizophrenia, study finds 2Health News:Entries Open for 2014 HREI Insights Awards™ 2Health News:Entries Open for 2014 HREI Insights Awards™ 3Health News:Entries Open for 2014 HREI Insights Awards™ 4Health News:MarijuanaDoctors.com Responds to Massachusetts Company's Claim 2Health News:New Drug May Fight Serious Respiratory Virus in Infants 2Health News:New Drug May Fight Serious Respiratory Virus in Infants 3
    ... who undergo heart surgery fare better if they receive ... ,Investigators say that children who received reconstituted ... cells and plasma -- tended to accumulate less fluid, ... the study, researchers compared results for 200 infants who ...
    ... the brain using the CyberKnife frameless radiosurgery can successfully ... CyberKnife is a non-invasive robotic radiosurgical device that can ... uses a robotic arm, controlled by a computer, that ... tumor site. ,During the study researchers examined ...
    ... are obese when they are diagnosed with early-stage breast cancer ... women of normal weight.// ,Studies in the past have ... development, and has also shown to have contradictory results about ... latest study researchers say, they have demonstrated a significant association ...
    ... is an often disabling condition that affects primarily women. ... cannot be overcome with rest and often worsens with ... and there are no diagnostic tests or cures. A ... are at increased risk for developing chronic fatigue later ...
    ... in restoring sudden onset hearing loss. Researchers say sudden hearing ... of the sudden hearing loss can be identified in only ... includes viral and bacterial diseases, and metabolic, neurologic and immunologic ... which case there is no known cause. ,Previous research ...
    ... that affects more than 80 percent of teenagers and up ... cited // as a source of acne, these claims have ... this study. Each participant had at least one academic examination ... sources of stress for students. Stress levels were recorded using ...
    Cached Medicine News:
    ...
    ...
    Bimanual I&A Cannulas. Curved 45 with a .51mm open-end irrigation port. Facilitates removal of cortical debris between 10-2 o'clock. .80mm x 17.0mm...
    ...
    Medicine Products: