Navigation Links
Phase 2b Study of Boehringer Ingelheim's Interferon-Free Hepatitis C Treatment Shows Undetectable Virus in HCV Genotype-1 Patients 12 Weeks After Treatment Ended (SVR12)
Date:4/19/2012

pean Association of the Study of the Liver (EASL 2012) in Barcelona, Spain (Abstract #101). These results supplement the abstract findings highlighted today during an official EASL press conference.

"We are looking forward to the final results from this study, that we hope will be a significant step towards an interferon-free future for patients with HCV," said Peter Piliero, M.D., Vice President, Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc. "We are committed to the millions of people around the world who are chronically infected with HCV. Through our clinical trial program HCVerso™, we are working with experts worldwide to ask the difficult questions that remain in HCV to find answers to the challenges that these patients face."

Planning of the interferon-free Phase 3 clinical trial program is underway.

SOUND-C2 Pre-Specified Interim AnalysisIn this open-label Phase 2b study, 362 treatment-naive GT1 HCV patients were randomized into five interferon-free treatment groups, each with 120 mg BI 201335 QD, but with different dosing of BI 207127 and treatment durations. The randomization was stratified by HCV genotype (1a or 1b) and patient IL-28B genotype, with 41 percent of patients being GT1a and 75 percent being IL-28B CT or TT.SOUND-C2 Trial Design and Interim ResultsBI 201335

BI 207127

RBV

Treatment
Duration

SVR12
n (%)A

N=81

120 mg QD

600 mg TID

Y

16 wks

48 (59%)N=80

120 mg QD

600 mg TID

Y

28 wks

49 (61%)C

N=77

120 mg QD

600 mg TID

Y

40 wks

N/A*D

N=78

120 mg QD

600 mg BID

Y

28 wks

53 (68%)E

N=46

120 mg QD

600 mg TID

N

28 wks

18 (39%)* SVR12 data for the 40 week arm of SOUND-C2 is n
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. CrystalGenomics Announces Positive Results from Phase 2b Osteoarthritis Study of CG100649
2. Morphotek®, Inc. Announces Initiation of MORAb-004 Phase 2 Study in Metastatic Colorectal Cancer
3. Encouraging Phase III Study Results Show PET Imaging with Florbetaben Reliably Detects Beta-Amyloid in the Brain
4. QRxPharma Successfully Completes Phase 1 Studies for MoxDuo® CR
5. Enanta Announces Positive Phase 2 Results From Interferon-Free Combination Studies with ABT-450 for Hepatitis C Treatment to be Presented at EASL
6. UCB and Amgen Initiate Sclerostin Antibody Phase 3 Program in Patients With Postmenopausal Osteoporosis
7. Bionovos Independent Data Safety Monitoring Board Recommends Continuation of Phase 3 Study for Menerba™
8. Neurocrine Announces Phase II Results of VMAT2 Inhibitor NBI-98854 for Treatment of Tardive Dyskinesia
9. iBio Announces Successful Completion of H1N1 Influenza Vaccine Phase 1 Clinical Trial
10. Avaxia Biologics Awarded $1.5 Million Phase II SBIR Grant from NIH to Develop Oral Antibody Therapeutic for Inflammatory Bowel Disease
11. Johnson & Johnson to Provide Webcast Presentation of XARELTO® (rivaroxaban) Phase 3 Clinical Data Presented at the American College of Cardiologys Annual Scientific Sessions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... , May 28, 2015 Zimmer Holdings, ... it has finalized agreements with buyers to divest in ... Unicompartmental High-Flex Knee System assets, Biomet Discovery® Elbow System ... are in furtherance of Zimmer,s pending acquisition of Biomet, ... Zimmer continues to work constructively with the Bureau of ...
(Date:5/28/2015)... -- Maetrics ( http://maetrics.com ), a leading international consulting firm ... successful conference, "The cost of non-compliance -- How new regulation ... Zurich . Hosted by ... Switzerland -based team, experts provided insights on the ... an exclusive local audience. The event was held in ...
(Date:5/28/2015)... , May 28, 2015 The controversy ... )  in hysterectomies and myomectomies (procedures to remove uterine ... the FBI is investigating Johnson & Johnson,s Ethicon, ... of the devices. According to the report published ... th , the FBI is trying to determine ...
Breaking Medicine Technology:Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 2Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 3Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 4Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 5Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 6Maetrics Hosts Innovative Medical Cluster Event in Switzerland 2Power Morcellator Attorneys at Bernstein Liebhard LLP Comment on Report That FBI Is Investigating Ethicon Morcellators 2Power Morcellator Attorneys at Bernstein Liebhard LLP Comment on Report That FBI Is Investigating Ethicon Morcellators 3
... Inc., a private clinical-stage biotherapeutics company focused on the ... for cancer, today announced that the first patient has ... JX-594 as a neoadjuvant therapy in patients who are ... to the liver. The study is ...
... 21, 2011  Adeona Pharmaceuticals, Inc. (NYSE Amex: ... of Directors has taken several actions to prioritize the ... field of synthetic biology. As previously announced on November ... into a worldwide exclusive channel collaboration for the development ...
Cached Medicine Technology:Jennerex Announces First Patient Treated in Phase 2a Clinical Trial of JX-594 as a Neoadjuvant Therapy in Colorectal Cancer Patients Undergoing Surgery 2Jennerex Announces First Patient Treated in Phase 2a Clinical Trial of JX-594 as a Neoadjuvant Therapy in Colorectal Cancer Patients Undergoing Surgery 3Jennerex Announces First Patient Treated in Phase 2a Clinical Trial of JX-594 as a Neoadjuvant Therapy in Colorectal Cancer Patients Undergoing Surgery 4Jennerex Announces First Patient Treated in Phase 2a Clinical Trial of JX-594 as a Neoadjuvant Therapy in Colorectal Cancer Patients Undergoing Surgery 5Adeona Announces Proposed Name Change to Synthetic Biologics, Inc., and Appointment of John Monahan, Ph.D., as Senior Vice President of Research & Development 2Adeona Announces Proposed Name Change to Synthetic Biologics, Inc., and Appointment of John Monahan, Ph.D., as Senior Vice President of Research & Development 3Adeona Announces Proposed Name Change to Synthetic Biologics, Inc., and Appointment of John Monahan, Ph.D., as Senior Vice President of Research & Development 4
(Date:5/28/2015)... Florida (PRWEB) May 28, 2015 Boston ... and wife Beth, both Genesis Foundation Board of Directors ... John Havlicek Celebrity Fishing Tournament June 4-7. For the ... 4-day event benefitting The Genesis Foundation for children by ... cause. , The 34th John Havlicek Celebrity Fishing ...
(Date:5/28/2015)... May 28, 2015 " Trends Investing ” ... Report, which takes a look at small, medium, and large ... host of NewsWatch and business expert, conducted the business review ... users to where they should invest their money. , The ... concept. But doing it and knowing how to succeed ...
(Date:5/28/2015)... Workers’ compensation costs per claim in Michigan ... study by the Workers Compensation Research Institute (WCRI) ... , The WCRI study, CompScope™ Benchmarks for Michigan, 15th ... days or more of work with those of 16 other ... claim was 4 percent lower than similar claims from 2008. ...
(Date:5/28/2015)... Nidra Herbal Sleep Supplement features a 100% Ayurveda herbal ... supplement, Nidra Herbal Sleep Supplement is more than just a ... with a real sense of wellbeing the next day. ... as the “Science or Knowledge of Life”, was first used ... holistic system of knowledge which combines contemplation, herbal supplements and ...
(Date:5/28/2015)... Ticket Down is a reputable source of presale tickets ... Argentina in early September. , Two of the best ... pitch at AT&T Stadium in Arlington/Dallas, TX. Mexico and Argentina ... Tuesday, September 8th at 9 p.m. The match will feature ... some of the most loved players in the entire sport. ...
Breaking Medicine News(10 mins):Health News:The Genesis Foundation Prepares for Their Final Annual John Havlicek Celebrity Fishing Tournament 2Health News:An Application to Learn Where to Invest Money was Featured on NewsWatch Television 2Health News:Michigan Workers’ Compensation Costs Lower Than Most States, Says WCRI Study 2Health News:Ayurveda Herba Corp’s Revolutionary Herbal Sleep Supplement is Now Available from Amazon.com 2Health News:Mexico vs. Argentina Tickets at AT&T Stadium: Ticket Down Slashes Ticket Prices on Argentina vs. Mexico Presale Tickets at AT&T Stadium for 9/8/15 Friendly Match 2Health News:Mexico vs. Argentina Tickets at AT&T Stadium: Ticket Down Slashes Ticket Prices on Argentina vs. Mexico Presale Tickets at AT&T Stadium for 9/8/15 Friendly Match 3
... office visits with a diagnosis of bipolar disorder substantially ... a bipolar disorder diagnoses appeared to almost double, according ... of General Psychiatry, one of the JAMA/Archives journals. , ... periods of mania (an abnormally elevated mood) and depression. ...
... "Psoriasis Cure,Now," a nonprofit patient advocacy group, today released ... their kids head back to,school. The organization offers a ... off the internet and deliver to their child,s school,teacher; ... leading pediatric,dermatologist discussing how to treat psoriasis in children ...
... September 3 KFH has announced that it,has ... 13485 and ISO,9001:2000 quality management systems with the ... Sally Sennitt, MD, says: "We are delighted,to have ... working with BSI. It is a major milestone ...
... WASHINGTON, Sept. 2 New data about the ... news for thousands of,patients with cardiovascular disease, according ... These new findings,also underscore the crucial importance of ... implantation technique, and in prescribing a,strict regimen of ...
... -- Chinas efforts to control population growth in the ... in the future. , This prediction comes from a ... a year in China studying its geriatric policies and ... of internal medicine in the division of geriatric medicine ...
... Sept. 2 Oil Refineries Ltd. (TASE: ORL),(the "Company" ... has received a claim (the "Claim"), filed with the ... IDF units, against the Company,and nine other defendants. The ... plaintiffs allege they contracted due to their being in,the ...
Cached Medicine News:Health News:Study documents rapid increase in youth bipolar disorder diagnoses 2Health News:Psoriasis Cure Now offers 'Back to School' Resources for Parents of Children with Psoriasis 2Health News:Latest DES Analysis Stresses Importance of Physicians Well-Trained in Implantation Technique and Patient Follow-Up 2Health News:Latest DES Analysis Stresses Importance of Physicians Well-Trained in Implantation Technique and Patient Follow-Up 3Health News:China's 1-child policy could backfire on its elderly 2Health News:China's 1-child policy could backfire on its elderly 3Health News:Claim Filed Against the Company and Nine Other Defendants in the Haifa Magistrates Court 2
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
... Bulb Direct has been selling ... since 1996, and we are ... satisfaction guarantee. Check out our ... see our discount light bulbs ...
... Bulb Direct has been selling ... since 1996, and we are ... satisfaction guarantee. Check out our ... see our discount light bulbs ...
... Direct has been selling replacement ... 1996, and we are extremely ... guarantee. Check out our catalog ... our discount light bulbs specials. ...
Medicine Products: