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Pharsight Invited to Present on HIV Modeling and Simulation at ASCPT Annual Meeting
Date:3/28/2008

Dr. Bill Poland Will Present on Strategic Use of in Vitro and Literature

Data to Predict Effects of New HIV Therapies

MOUNTAIN VIEW, Calif., March 28 /PRNewswire-FirstCall/ -- Pharsight Corporation (Nasdaq: PHST), a leading provider of software, strategic consulting, and regulatory services for optimizing clinical drug development, today announced that Bill Poland, Ph.D., vice president and lead scientist, Strategic Consulting Services, has been invited to present at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting at the Orlando World Center Marriott Resort in Orlando, Florida. Dr. Poland will present on April 4, 2008, joining other leading experts from the pharmaceutical industry and academia in a symposium focused on applications of pharmacokinetic/pharmacodynamic (PK/PD) and disease modeling in HIV.

The symposium will provide a forum for scientific discussion and collaborative exchange on model-based approaches to describe and predict drug effects in the treatment of HIV, and will include specific case examples where drug-disease modeling have optimized the clinical development of new anti-HIV drugs. Dr. Poland's presentation, entitled "Using in Vitro and Literature Data to Predict Effects of New Anti-Retrovirals", will describe how PK/PD-viral dynamics models developed using preclinical data and literature data on existing HIV treatments can inform dose-response predictions for new anti-retroviral agents.

In addition to Dr. Poland's presentation, Pharsight scientists have contributed to two separate ASCPT poster presentations that describe model-based approaches to support development decision-making and clinical trial design for drug candidates in oncology an
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