Navigation Links
Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)
Date:1/14/2008

nsitivity to Vidaza or mannitol and in patients with advanced malignant hepatic tumors.

In clinical studies, the most commonly occurring adverse reactions by SC route were nausea (70.5%), anemia (69.5%), thrombocytopenia (65.5%), vomiting (54.1%), pyrexia (51.8%), leukopenia (48.2%), diarrhea (36.4%), fatigue (35.9%), injection site erythema (35.0%), constipation (33.6%), neutropenia (32.3%) and ecchymosis (30.5%). Other adverse reactions included dizziness (18.6%), chest pain (16.4%), febrile neutropenia (16.4%), myalgia (15.9%), injection site reaction (13.6%), aggravated fatigue (12.7%) and malaise (10.9%). The most common adverse reactions by IV route also included petechiae (45.8%), rigors (35.4%), weakness (35.4%) and hypokalemia (31.3%).

Because treatment with Vidaza is associated with neutropenia and thrombocytopenia, complete blood counts should be performed as needed to monitor response and toxicity, but at a minimum, prior to each dosing cycle. Because Vidaza is potentially hepatotoxic in patients with severe pre-existing hepatic impairment, caution is needed in patients with liver disease. In addition, Vidaza and its metabolites are substantially excreted by the kidneys and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, it may be useful to monitor renal function.

Vidaza may cause fetal harm. While receiving treatment with Vidaza, women of childbearing potential should avoid becoming pregnant, and men should avoid fathering a child. In addition, women treated with Vidaza should not nurse.

About Pharmion

Pharmion is a leading global oncology company uniquely focused on acquiring, developing and commercializing innovative products for the treatment of hematology and oncology patients in the U.S., Europe and additional international markets. Pharmion has a number of products on the market including t
'/>"/>

SOURCE Pharmion Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
2. Pharmions Amrubicin Shows Encouraging Results Compared to Standard of Care in Second Line Treatment of Small Cell Lung Cancer
3. Pharmion and MethylGene Report Preliminary MGCD0103 Clinical Data at the 2007 AACR-NCI-EORTC International Conference
4. Pharmion Initiates Pivotal Phase 3 Study of Amrubicin in Small Cell Lung Cancer
5. Pharmion and MethylGene Initiate Phase One Combination Clinical Trial with MGCD0103 and Taxotere(R) in Patients with Solid Tumors
6. Pharmion and MethylGene Announce U.S. Orphan Drug Designation Granted for MGCD0103 for the Treatment of Hodgkins Lymphoma
7. Takeda Submits New Drug Application for Alogliptin (SYR-322) in the U.S.
8. AstraZeneca Submits sNDAs for SEROQUEL XR(TM) for the Treatment of Bipolar Mania and Bipolar Depression
9. Roche Submits Application for FDA Approval of ACTEMRA(R) for the Treatment of Rheumatoid Arthritis
10. Peregrine Pharmaceuticals Submits Clinical Protocol for New Phase II Trial of Bavituximab in Patients With Metastatic Breast Cancer
11. Vanda Pharmaceuticals Submits Iloperidone New Drug Application
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... -- The Assistance Fund announces the addition of its ... for copay to individuals diagnosed with Melanoma. ... the Melanoma Copay Assistance Program to our portfolio of ... "With each additional program we are closer to achieving ... one is denied access to medications due to an ...
(Date:5/22/2015)... NEW YORK , May 22, 2015 /PRNewswire/ ... segment of the $13 billion global cardiac rhythm ... Kalorama Information.  Kalorama found that Medtronic, St. Jude ... Medical) command 80% of this market segment. The ... Management Device Markets , uses 2015 as a ...
(Date:5/22/2015)...  RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX), a clinical-stage drug ... today announced that J.J. Finkelstein , chief executive ... overview at two upcoming investor conferences. ... Annual Microcap Conference on Thursday May 28, 2015 ... 11:00 am EDT.  A webcast will be available at ...
Breaking Medicine Technology:The Assistance Fund Adds Melanoma Assistance Program 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4RegeneRx to Present at 2 Investor Conferences 2RegeneRx to Present at 2 Investor Conferences 3
... Feb. 7, 2011 Cancer ... served by just 11 modern radiotherapy linear accelerators, now ... Systems (NYSE: VAR). Treatments using fast and efficient RapidArc® ... Clinac® iX medical linear accelerator at the new United ...
... 7, 2011 Medivation, Inc. (Nasdaq: MDVN ) ... officer, will present at the 13th Annual BIO CEO & ... Time at the Waldorf-Astoria in New York. Dr. ... development programs for MDV3100 for prostate cancer and dimebon (latrepirdine) ...
Cached Medicine Technology:Cancer Patients in Bangladesh Gain Access to Advanced RapidArc Radiotherapy Treatments from Varian Medical Systems 2Cancer Patients in Bangladesh Gain Access to Advanced RapidArc Radiotherapy Treatments from Varian Medical Systems 3
(Date:5/22/2015)... Pioneer Millworks, the largest reclaimed wood company in ... reclaimed wood, introducing their latest reclaimed wood products at ... offerings, Vat 35, Reclaimed Teak , and Prairie ... largest design event. , “Designers, architects, builders, and homeowners ... see and feel the variety of wood surfaces in ...
(Date:5/22/2015)... 22, 2015 Hundreds of federal ... of individuals who allegedly experienced serious internal bleeding ... to move forward in the U.S. District Court, ... Order dated May 4, 2015, the Court has ... electronically stored information. Among other things, the Order ...
(Date:5/22/2015)... May 22, 2015 Hands On HealthCare ... 17, 2015, the Annual One Day Sale on ... Hands On HCMT offers drastically reduced certificates one day a ... have enough sessions, through what used to be the slowest ... for the community as well. This once a year occurrence ...
(Date:5/22/2015)... Boston, Massachusetts (PRWEB) May 22, 2015 ... conditions is a difficult process. Historically providers have ... efforts by payers. Starting in 2015, Medicare has ... care coordination activities. Thanks to the launch of ... technology, providers and health systems using the platform ...
(Date:5/22/2015)... Coco Libre, the Official Coconut Water of ... at the 104th running of the race. On Sunday, May ... 315 people in one hour—one person about every 10 seconds. ... true to the heart of the Bay Area, so unique, ... to the finish line only made sense,” said Jennifer Goodrum, ...
Breaking Medicine News(10 mins):Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 2Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 4Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 3Health News:Oculus Health Care Coordination Platform Officially Launched 2Health News:Oculus Health Care Coordination Platform Officially Launched 3Health News:Oculus Health Care Coordination Platform Officially Launched 4Health News:Coco Libre Ice Luge Sets New World Record at Bay to Breakers 2
... out simultaneous raids on some government hospital doctors and ... Monday.// ,The raids were conducted in Chennai, Goa, ... the investigating agency said., ,The houses of Sudha ... Goel of Sucheta Kriplani Hospital here were searched, he ...
... UP TO a third of cancer patients at a leading National ... put up in nearby hotels under plans to save tens of ... a report in the Sunday Times, over 100 patients suffering from ... have already stayed at NHS expense at the Radisson Edwardian Grafton, ...
... announced that U.S. Food Drug Administration (US FDA) ... & 500 mg.// ,Cephalexin is used to ... as bronchitis, tonsillitis, ear infections, skin infections, and ... milestone by obtaining the first product approval from ...
... cases in India is probably much higher than official data ... ,India, which has 5.1 million people with AIDS or ... in 2005 that new infections had sharply fallen to 28,000 ... aid groups have expressed skepticism about those figures. Peter ...
... that your problem solving abilities could be affected by something ... a movie?// True say Ohio State University Medical Center researchers, ... The study is the first of its kind to deal ... very different movies - "Saving Private Ryan" and "Shrek" were ...
... only to South Africa with respect to the number of ... AIDS in India has revealed that the figures could be ... been numerous repots claiming a dramatic decline in the number ... following the release of the U.N. annual global report on ...
Cached Medicine News:Health News:Hospital Cuts Costs By Moving Cancer Patients To Hotels 2Health News:Stress Levels Determine Problem-Solving Abilities Of An Individual 2Health News:AIDS Picture In India Not As Rosy As It Seems To Be 2
An automatic system for determining erythrocyte sedimentation rate (ESR) in EDTA tube and using cell counter racks....
... of automatic systems for performing erythrocyte sedimentation ... blood. With the introduction of the Ves-matic ... market a truly revolutionary testing system which ... with the traditional ESR techique.,By means of ...
MiniVes has been specifically designed for the doctors office and near patient testing and it uses normally freshly collected blood that shall be mixed manually by 15 complete inversion of the tube a...
... VACUETTE® erythrocyte sedimentation rate analysers, ... The new generation unites the well-established ... whole range of additional innovations which ... erythrocyte sedimentation rate. Cost effectiveness is ...
Medicine Products: