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Pharmaxis Launches ARIDOL® (Mannitol Inhalation Powder) Bronchial Challenge Test Kit for the Assessment of Bronchial Hyperresponsiveness
Date:2/23/2011

EXTON, Pa., Feb. 23, 2011 /PRNewswire/ -- Pharmaxis, a global specialty pharmaceutical company focused on therapeutic products for chronic respiratory and immune disorders, announced today the commercial launch of ARIDOL® (mannitol inhalation powder) Bronchial Challenge Test Kit, the first new bronchial challenge test in more than two decades and the company's first product launch in the U.S.  ARIDOL is used to assess bronchial hyperresponsiveness in patients six years of age and older who do not have clinically apparent asthma.  ARIDOL should not be used as a stand alone test to assess asthma or as a screening test for asthma, but as part of a physician's overall assessment of asthma.  ARIDOL can be ordered directly from Pharmaxis and is available to pulmonary function labs and physicians' offices by calling Pharmaxis Customer Service at 1-888-416-1828.  

"ARIDOL is an important advancement in bronchial challenge testing – the first in 20 years – and a significant addition to the tools available to help in an overall assessment of asthma," said Stephen Beckman, President, Pharmaxis, Inc.  "We are excited to provide patients and the medical community with an effective, accurate and reproducible test that can be conducted in the convenience of a pulmonary function lab or physician's office."

ARIDOL is a single-use, indirect test that is easy-to-administer, requires minimal preparation time and a 15% reduction in lung function from baseline for a positive test.  ARIDOL was approved by the U.S. Food and Drug Administration (FDA) on October 5, 2010, and demonstrated safety and efficacy in two Phase III clinical trials.

"The ARIDOL Bronchial Challenge Test takes only about 20 minutes to administer for a positive test and requires a 15% reduction in FEV[1].  Previous options may take up to 40 minutes to implement and require a 20% reduction in FEV[1]," said Bradley Chipps, MD, Capit
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SOURCE Pharmaxis, Inc.
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