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Pharmaxis Announces Positive Combined Phase 3 Cystic Fibrosis Trial Results
Date:10/22/2010

signation from the European Medicines Agency.

About Cystic Fibrosis

In a healthy person, there is a constant flow of mucus over the surfaces of the air passages in the lungs, removing debris and bacteria.  In CF, an inherited disease, a defective gene disrupts ion transport across the epithelial membrane within cells. In the lungs, this leads to a depletion of the airway surface liquid that normally bathes the cilia, and a resultant reduction in mucociliary clearance.  The result is thick, sticky mucus that clogs the lungs, severely restricting the natural airway-clearing process.  It also increases the potential for bacteria to become trapped and for inflammation, thus creating an unhealthy lung environment that leads to life-threatening lung infections.

About the North American Cystic Fibrosis Conference (NACFC)

The NACFC is a scientific conference designed exclusively for medical professionals in the field of CF study and care and is attended by over 3,000 physicians, research scientists, nurses, social workers, nutritionists, dieticians, physical therapists, respiratory therapists, pharmacists, psychologists, psychiatrists and research coordinators.  The conference offers more than 70 educational and scientific sessions on the latest CF research and therapies, as well as a showcase of CF-related products and services.  Educational topics include the importance of newborn screening, advancements in drug discovery and development, the importance of clinical trials, quality improvement and patient outcomes, comprehensive lung care, and improving nutrition care.

About the Cystic Fibrosis Foundation (CFF)

The Cystic Fibrosis Foundation is the world's leader in the search for a cure for cystic fibrosis.  The Foundation funds more CF research than any other organization, and nearly every CF drug available today was made possible because of Foundation support.  Based in Bet
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