Navigation Links
Pharmasset Receives Notice of Allowance
Date:6/26/2008

-USPTO to grant patent covering the anti-HCV drug PSI-6130 and its active

metabolites

PRINCETON, N.J., June 26 /PRNewswire-FirstCall/ -- Pharmasset, Inc. (Nasdaq: VRUS) announced that the United States Patent and Trademark Office has issued a Notice of Allowance for patent application Serial No. 10/828,753 titled, "Modified Fluorinated Nucleoside Analogues," covering the composition of matter of a family of molecules invented at Pharmasset for the treatment of hepatitis C virus (HCV), including PSI-6130 and the active metabolite of PSI-7851. R7128, a prodrug of PSI-6130, a nucleoside analogue polymerase inhibitor of HCV, is being developed through Pharmasset's collaboration with Roche. PSI-7851 is a proprietary nucleotide analogue polymerase inhibitor of HCV that Pharmasset has nominated as a lead development candidate.

"We are pleased that the USPTO has recognized our intellectual property rights in our growing pipeline of HCV nucleoside polymerase inhibitors," stated Schaefer Price, Pharmasset's Chief Executive Officer. "The success that our in-house research team has had in discovering new HCV product candidates can now be translated into potentially significant commercial value."

About R7128

R7128 is being developed for the treatment of chronic HCV infection. R7128 is a prodrug of PSI-6130, a cytidine nucleoside analog inhibitor of HCV RNA polymerase. A prodrug is a chemically modified form of a molecule designed to enhance the absorption, distribution and metabolic properties of that molecule. Results from an oral single ascending dose study of PSI-6130 in 24 healthy male volunteers showed that PSI-6130 was generally well tolerated with no serious adverse events in doses up t
'/>"/>

SOURCE Pharmasset, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
2. Pharmasset Commences Dosing in Phase 3 Registration Studies of Clevudine for HBV
3. Pharmasset Commences Dosing in 28-Day Combination Study of R7128 with Pegasys(R) plus Copegus(R) for Hepatitis C
4. Pharmasset Announces Clevudine and R7128 Presentations at HEP-DART
5. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
6. Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile
7. Pharmasset Reports First Fiscal Quarter 2008 Financial Results
8. Pharmasset Presents Results of 4-Week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
9. Pharmasset Commences Dosing R7128 Cohorts 3 and 4 for the Treatment of Chronic Hepatitis C
10. Pharmasset Nominates PSI-7851 as a Lead Development Candidate for the Treatment of Chronic Hepatitis C
11. Reclast(R) Receives US FDA Approval as First and Only Once-Yearly Treatment for Women With Postmenopausal Osteoporosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... 2014 Capnia, Inc. (NASDAQ: ... diagnostics based on its proprietary Sensalyze™ Technology Platform ... financial results for the third quarter and nine ... the completion of our initial public offering (IPO), ... recently initiated CoSense® commercial launch," said Anish Bhatnagar, ...
(Date:12/19/2014)... Dec. 18, 2014 Since last month,s FBI ... now known as the leading online black market for ... growth in its offering of drugs and other illegal ... the takedowns did succeed in lowering the numbers of ... of the markets in August. But some new sites ...
(Date:12/19/2014)... separating membrane market has witnessed robust development with the growth ... a later starter. In 2012, the size of ... with the proportion worldwide soaring to 16.3%. It is projected ... continue its growth rate by around 20% in the upcoming ... roughly RMB25 billion. An integrated membrane industrial system ...
Breaking Medicine Technology:Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 3Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3
...  This year, five leading non-profits at the forefront ... from a generous bequest of approximately $10 million ... Hailey. The gift will dramatically increase these organizations, ... about health and drug policy. Half ...
... Stereotaxis, Inc. (NASDAQ: STXS ) today ... as Chairman of its Board of Directors, effective immediately.  ... of growing companies in the medical technology and biotechnology ... remain on the Board of Directors as an independent ...
Cached Medicine Technology:Software Pioneer Leaves $10 Million Bequest To Five Leading Non-profits In Health And Drug Policy Reform 2Software Pioneer Leaves $10 Million Bequest To Five Leading Non-profits In Health And Drug Policy Reform 3Stereotaxis Appoints William C. Mills III as Chairman of Board of Directors 2Stereotaxis Appoints William C. Mills III as Chairman of Board of Directors 3
(Date:12/19/2014)... December 19, 2014 Diet Doc strives ... current approach to weight loss by combining ... The professionals at the company understand that remaining committed ... effects of eliminating carbohydrates and sugars from the diet ... to abandon their weight loss goals. , For ...
(Date:12/19/2014)... Novellus Healthcare Communications, LLC announces ... Clinics™, an independent journal that provides practical information ... for patients inside the pharmacy and retail clinics. ... optimal access to quality care, Inside Patient Care: ... team treating and coordinating patient care in pharmacies ...
(Date:12/19/2014)... Slone Partners , a ... healthcare information technology, and laboratory testing industries, has ... Operating Officer. The announcement comes after a year ... strengthened presence in Boston and several new additions ... breathes the client experience," said Adam Slone, Chief ...
(Date:12/19/2014)... THURSDAY, Dec. 18, 2014 (HealthDay News) -- Being in good ... researchers report. They looked at data from more than ... who underwent treadmill tests between 1991 and 2009. Those ... chance of having high blood pressure at the start of ... with high levels of fitness. Of the more than ...
(Date:12/19/2014)... 2014 (HealthDay News) -- Traveling through the same U.S. ... to three others within a four-hour time span, illustrating ... report shows. "The exposures in this report were ... an international terminal, highlighting the fact that measles is ... an infectious disease specialist at the U.S. Centers for ...
Breaking Medicine News(10 mins):Health News:Diet Doc Incorporates Appetite Zap into their Already Impressive Collection of Diet Products to Jump Start the Metabolism and Burn Fat 4X Faster 2Health News:Diet Doc Incorporates Appetite Zap into their Already Impressive Collection of Diet Products to Jump Start the Metabolism and Burn Fat 4X Faster 3Health News:Diet Doc Incorporates Appetite Zap into their Already Impressive Collection of Diet Products to Jump Start the Metabolism and Burn Fat 4X Faster 4Health News:The Transformation of Retail Pharmacies into a Healthcare Delivery Center 2Health News:The Transformation of Retail Pharmacies into a Healthcare Delivery Center 3Health News:Slone Partners Promotes Leslie Loveless to Chief Operating Officer 2Health News:Being Fit Keeps Blood Pressure in Check 2Health News:Arriving Now at Gate 42: Measles 2Health News:Arriving Now at Gate 42: Measles 3
... N.J., July 23 The New Jersey,Hospital Association,s ... planning grant for $199,502 from the Robert Wood ... the quality of,healthcare in New Jersey., The ... months whether New,Jersey can be represented in RWJF,s ...
... Laura Kolkman, President,Mosaica Partners, a nationally recognized ... to serve as Chair of the Healthcare,Information ... (HIE) Steering Committee., The HIE Steering ... including providers, payers, vendors, consultants and life,sciences, ...
... is a central component of engaging in conversation, but people ... a social interaction. New research from Carnegie Mellon University sheds ... social difficulties in autism, and on the workings of these ... to the study, which is available on the Web site ...
... software has recently added advanced features like shared whiteboard, chat and screen ... only available for a high cost with paid services like Webex. Also ... you log into your home or office PC from anywhere on the ... ...
... from Napa Valley and North Coast Appellations is offering the first ... providing excellent value for the fine wine consumer and collector. ... ... 2008 -- Fairhope Vintners, a producer of classically styled wines from ...
... (ACCP) invites journalists from around the world to ... assembly, held October 25-30, in Philadelphia, PA. CHEST ... clinical chest medicine, including pulmonology, critical care, cardiology, ... address, session topics, special events, or Philadelphia tourism, ...
Cached Medicine News:Health News:Mosaica Partners' Kolkman to Chair HIMSS Healthcare Information Exchange Steering Committee 2Health News:Autism's social struggles due to disrupted communication networks in brain 2Health News:How to Conduct Free Web Meetings and Remote Desktop? 2Health News:Fairhope Vintners Offers First Release of Classically Styled Napa Valley Cabernet Sauvignon Wines 2Health News:Fairhope Vintners Offers First Release of Classically Styled Napa Valley Cabernet Sauvignon Wines 3Health News:CHEST 2008 Philadelphia: Media registration open 2
Patient Monitor...
... primers and a FAM-labeled probe that is designed ... probe to detect Flu B. In addition, this ... for a separate sample processing control. This ASR ... 532 and Texas Red reporter dyes such as ...
... primers and a FAM-labeled probe that is designed ... mecA gene. In addition, this ASR contains primers, ... internal control sequence. This ASR requires an instrument ... dyes such as the Cepheid SmartCycler System. The ...
... primers and a FAM-labeled probe that is ... In addition, this ASR contains primers, a ... control sequence. This ASR requires an instrument ... reporter dyes such as the Cepheid SmartCycler ...
Medicine Products: